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Researchers develop new exosome formulation to deliver VEGF antibodies for synergistic therapy

Researchers from the Institute of Process Engineering of the Chinese Academy of Sciences, Beijing Chaoyang Hospital and the University of Queensland have developed a new formulation based on regulatory T-cell exosomes (rEXS) to deliver vascular endothelial growth factor (VEGF) antibodies for choroidal neovascularization therapy.

26 Jul 2021

Study reveals safety of second mRNA COVID-19 vaccine dose after allergic reactions to first dose

In a multi-hospital analysis of individuals who experienced an allergic reaction to their first mRNA COVID-19 vaccine dose, all patients who went on to receive a second dose tolerated it without complications.

26 Jul 2021

Mount Sinai researchers use cerebral organoids to study frontotemporal dementia

Frontotemporal dementias are a group of fatal and debilitating brain disorders for which there are no cures.

26 Jul 2021

Excessive body fat can increase the risk of dementia

It's the global epidemic that affects two in every five adults, but as obesity continues to expand waistlines worldwide, researchers at the University of South Australia are warning that harmful body fat can also increase the risk of dementia and stroke.

26 Jul 2021

As holdout Missouri joins nation in monitoring opioid prescriptions, experts worry

Kathi Arbini said she felt elated when Missouri finally caught up to the other 49 states and approved a statewide prescription drug monitoring program this June in an attempt to curb opioid addiction.

26 Jul 2021

The pandemic made telemedicine an instant hit. Patients and providers feel the growing pains.

Crystal Joseph pays for two telemedicine video services to ensure that her small therapy practice in Silver Spring, Maryland, can always connect with its clients.

26 Jul 2021

COVID-19 lockdown linked to fall in early childhood vaccination in England, a rise in Scotland

The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to numerous and sweeping restrictions in many countries, including the UK, limiting social and economic activity.

26 Jul 2021

Positive future orientation and strong parental support linked with lower risk of youth vaping

Adolescents who set goals for their future and those with strong parental support are less likely to use e-cigarettes and other tobacco products, according to a study by UPMC Children's Hospital of Pittsburgh and University of Pittsburgh School of Medicine physician-scientists.

26 Jul 2021

Comprehensive genomic sequencing essential to capitalize precision medicine for pediatric cancer care

St. Jude Children's Research Hospital investigators have demonstrated that comprehensive genomic sequencing of all pediatric cancer patients is feasible and essential to capitalize on the lifesaving potential of precision medicine.

26 Jul 2021

Nasal swabs reveal muted antiviral response in patients who developed severe COVID-19

Over the past 18 months, researchers have learned much about COVID-19 and its viral cause, SARS-CoV-2. They know how the virus enters the body, coming in through the nose and mouth and beginning its infection in the mucus layers of the nasal passageway.

26 Jul 2021

Novel atlas charts how different antibodies attack a major piece of SARS-CoV-2 machinery

As the SARS-CoV-2 virus that causes COVID-19 continues to evolve, immunologists and infectious diseases experts are eager to know whether new variants are resistant to the human antibodies that recognized initial versions of the virus.

26 Jul 2021

SARS-CoV-2 delta variant associated with several vaccine breakthrough cases in Houston

Their findings reveal that about 58% of all new coronavirus disease 2019 (COVID-19) cases are due to the delta variant and that the prevalence of vaccine breakthrough cases associated with the variant is as high as 20%. The study is currently available on the medRxiv* preprint server while awaiting peer review.

25 Jul 2021

Novel therapeutic agent could be effective for treating cancers with certain gene mutations

Mount Sinai researchers have developed a therapeutic agent that shows high effectiveness in vitro at disrupting a biological pathway that helps cancer survive, according to a paper published in Cancer Discovery, a journal of the American Association for Cancer Research, in July.

23 Jul 2021

Better healthcare processes can reduce the risk of delirium among elderly patients

Elderly patients with neurological conditions are significantly more likely to develop delirium shortly after they are hospitalized.

23 Jul 2021

Bacteria use a 'sense of touch' mechanism to navigate on surfaces

Many disease-causing bacteria such as Pseudomonas aeruginosa crawl on surfaces through a walk-like motility known as "twitching". Nanometers-wide filaments called type IV pili are known to power twitching, but scientists ignore which sensory signals coordinate the microbes' movements.

23 Jul 2021

MUSC Hollings Cancer Center part of promising phase 2 lymphoma clinical trial

MUSC Hollings Cancer Center was one of 28 clinical sites around the world that participated in the LOTIS-2 trial to test the efficacy of Loncastuximab tesirine, a promising new treatment for aggressive B-cell lymphoma.

23 Jul 2021

Blunted antiviral responses in the nasopharynx may underlie severe COVID-19

The body's first encounter with SARS-CoV-2, the virus behind COVID-19, happens in the nose and throat, or nasopharynx. A new study in the journal Cell suggests that the first responses in this battleground help determine who will develop severe disease and who will get through with mild or no illness.

23 Jul 2021

New machine learning-based model predicts mortality risk of intensive care unit patients

A research team led by Dr Rosario Delgado from the UAB Department of Mathematics, in collaboration with the Hospital de Mataró, developed a new machine learning-based model that predicts the risk of mortality of intensive care unit patients according to their characteristics.

23 Jul 2021

Clinical trials during a pandemic – lessons from COVID-19

In this interview, Dr. Benedicte Roquebert, Dr. Stephanie Haim-Boukobza and Dr. Souad Mehlal discuss how COVID-19 has resulted in new ways to think about clinical trials during a pandemic.

From Cerba Research 23 Jul 2021

Pre-transplant cardio-cerebrovascular diseases impact hematopoietic cell transplant outcomes

Hematopoietic cell transplantation (HCT) is a recognized treatment option for certain blood and bone marrow cancers as well as some autoimmune and hereditary disorders.

23 Jul 2021

Hospital News and Research

Researchers develop new exosome formulation to deliver VEGF antibodies for synergistic therapy

Study reveals safety of second mRNA COVID-19 vaccine dose after allergic reactions to first dose

Mount Sinai researchers use cerebral organoids to study frontotemporal dementia

Excessive body fat can increase the risk of dementia

As holdout Missouri joins nation in monitoring opioid prescriptions, experts worry

The pandemic made telemedicine an instant hit. Patients and providers feel the growing pains.

COVID-19 lockdown linked to fall in early childhood vaccination in England, a rise in Scotland

Positive future orientation and strong parental support linked with lower risk of youth vaping

Comprehensive genomic sequencing essential to capitalize precision medicine for pediatric cancer care

Nasal swabs reveal muted antiviral response in patients who developed severe COVID-19

Novel atlas charts how different antibodies attack a major piece of SARS-CoV-2 machinery

SARS-CoV-2 delta variant associated with several vaccine breakthrough cases in Houston

Novel therapeutic agent could be effective for treating cancers with certain gene mutations

Better healthcare processes can reduce the risk of delirium among elderly patients

Bacteria use a 'sense of touch' mechanism to navigate on surfaces

MUSC Hollings Cancer Center part of promising phase 2 lymphoma clinical trial

Blunted antiviral responses in the nasopharynx may underlie severe COVID-19

New machine learning-based model predicts mortality risk of intensive care unit patients

Clinical trials during a pandemic – lessons from COVID-19

Pre-transplant cardio-cerebrovascular diseases impact hematopoietic cell transplant outcomes

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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