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Moffitt researchers develop efficient method for creating mouse models to study melanoma

Genetically engineered mouse models are often used by scientists to study how the addition, deletion or mutation of genes affects the development of disease and effects of drugs.

17 Dec 2019

Pilot study shows strong results for genicular artery embolization to treat OA-related knee pain

A new study published in Journal of Vascular and Interventional Radiology details the first study of its kind in the U.S. to examine the use of genicular artery embolization (GAE) for extended treatment of knee pain caused by osteoarthritis.

17 Dec 2019

Researchers identify novel genetic signature with prognostic value for certain breast cancers

Researchers have identified a genetic signature with prognostic value for certain kinds of breast cancer. The discovery also contributes to a better understanding of the molecular mechanisms of pathological angiogenesis, the aberrant proliferation of blood vessels that occurs during cancer and other diseases.

17 Dec 2019

Study finds new drivers of destructive inflammation

Scientists describe in Nature Immunology an entirely new molecular process in mice that triggers T cell-driven inflammation and causes different auto-immune diseases.

17 Dec 2019

Researchers identify protein that is key for successful viral DNA uncoating

Viruses have been part of animals and humans for eons. When viruses invade a cell, they can infiltrate the nucleus with their genome and become part of the genome of the infected organism. Viruses transfer their genes between various organisms, as well as between tissues containing well differentiated cells inside a living creature. But how they uncoat their well-packed genes and release them to cause infection is largely unknown.

17 Dec 2019

Australian researchers find new drug target for preventing the spread of malaria

Australian researchers have found a new drug target for stopping the spread of malaria, after successfully blocking the world's deadliest malaria parasite - Plasmodium falciparum - from completing the 'transmission stage' of its lifecycle.

17 Dec 2019

Zebrafish 'avatars' help distinguish radiosensitive from radioresistant tumors

Radiotherapy can effectively reduce or even eliminate some tumors; others, however, show enduring resistance. Considering the potentially harmful side effects of radiotherapy, clinicians agree that it is paramount to be able to determine if a patient will benefit from radiotherapy before exposing them to any of the associated risks.

17 Dec 2019

Using bacterial nano-syringes as drug transporters in medicine

Pathogens can use a range of toxins to damage their host organism. Bacteria, such as those responsible for causing the deadly Plague, use a special injection mechanism to deliver their poisonous contents into the host cell.

17 Dec 2019

Antioxidant in green tea plant could be key to fighting tuberculosis

An antioxidant found in the green tea plant could become key to tackling tuberculosis one day, a team of international scientists led by Nanyang Technological University, Singapore has found.

17 Dec 2019

Researchers block malaria parasite’s ability to spread infection

Researchers have discovered a new way to prevent the deadliest malaria parasite from spreading infection.

17 Dec 2019

A promising cellular target for migraine attacks

A recent study published in the journal Cephalalgia, the official journal of the International Headache Society, reported an intriguing discovery.

17 Dec 2019

Researchers demonstrate a novel method for treating multiple sclerosis

Measuring changes in the speed of electrical signals along nerves connecting the eyes to the brain may accurately reflect recovery from myelin loss in multiple sclerosis (MS), according to researchers at the University of Wisconsin–Madison, and could be used to evaluate new treatments for the disease.

17 Dec 2019

New gene therapy has potential to reverse disease processes

Scientists have developed a new gene-therapy technique by transforming human cells into mass producers of tiny nano-sized particles full of genetic material that has the potential to reverse disease processes.

17 Dec 2019

Study: Chemoradiation regimen for Stage III NSCLC is better than two tested alternatives

Lung cancer is the leading cause of cancer death in the United States and approximately 75-80% of all cases are non-small cell lung cancer (NSCLC).

17 Dec 2019

New program to prevent driving under the influence of alcohol, cannabis and prescription drugs

Researchers at University of California San Diego School of Medicine will expand a statewide program to prevent driving under the influence of alcohol, cannabis and prescription drugs.

16 Dec 2019

Houston Methodist scientist proposes new combination treatment for Ewing sarcoma

Ewing sarcoma, an aggressive tumor that commonly affects bones in adolescents and young adults, is diagnosed in about 225 American children and teens every year, accounting for about 1 percent of pediatric cancers.

16 Dec 2019

Study finds dramatic increase in teen overdoses from anxiety drugs

The number of teens taking and overdosing from benzodiazepines, commonly prescribed anxiety medications, has risen dramatically over the past decade, according to a national study coauthored by Rutgers researchers.

16 Dec 2019

Immunotherapy: A promising new alternative to cancer therapies

Sophie Lucas, a researcher at the University of Louvain (UCLouvain) de Duve Institute, studies the immune responses that cancer patients can develop against their own tumor.

16 Dec 2019

Biocompatible hydrogels could help heal wounds, deliver drugs and treat cancer

Hydrogels for healing, synthesized from the molecules up by Rice University bioengineers, are a few steps closer to the clinic.

16 Dec 2019

Penn researchers track defective sperm epigenome linked to male infertility

One out of eight couples has trouble conceiving, with nearly a quarter of those cases caused by unexplained male infertility. For the past decade, research has linked that infertility to defective sperm that fail to "evict" proteins called histones from DNA during development.

16 Dec 2019