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UNM study to understand why and how DNA repair mechanisms go awry in cancer cells

DNA, like houses and cars, needs ongoing maintenance. Rays of ultraviolet sunlight, chemical pollutants and normal biochemical processes in the cell can damage it. Cells routinely repair this damage before making proteins or copying DNA for cell division. The repairs are remarkably accurate in normal cells but cancer cells make far more mistakes in fixing their DNA.

11 Dec 2012

Combination of diagnostic tests can predict conversion from MCI to Alzheimer's

A combination of diagnostic tests, including imaging and cerebrospinal fluid biomarkers can improve prediction of conversion from mild cognitive impairment (MCI) to Alzheimer's disease, according to a new study published online in the journal Radiology.

11 Dec 2012

Isis, Biogen Idec partner to discover and develop antisense drugs against neuromuscular disorders

Biogen Idec and Isis Pharmaceuticals, Inc. today announced that they have entered into a global collaboration agreement under which the companies will discover and develop antisense drugs against three undisclosed targets to treat neurological or neuromuscular disorders.

11 Dec 2012

Study examines 3 main relative contributors to pedestrian death

Worldwide, more than 1.2 million traffic fatalities occur yearly, and the lives of pedestrians account for a third of those lost. In the United States, pedestrians make up 12 percent of deaths from traffic collisions. According to a newly published study, male pedestrians struck by vehicles are more than twice as likely to die as their female counterparts.

11 Dec 2012

New taxes, Medicaid expansion requests and health insurance portability make health law news

News outlets examines a host of health law issues including new taxes on the rich -- set to soon take effect -- meant to pay for parts of the health law, governors' latest requests on expanding Medicaid, health insurance portability for older workers and dealing with chronic care.

11 Dec 2012

Study finds silent reading difficulties in glaucoma patients

Better strategies are needed to help glaucoma patients cope with difficulty reading. According to a new scientific study published in Investigative Ophthalmology & Visual Science, adults with glaucoma read slower when reading silently for long periods of time and are more likely to have their reading speed decrease over time, possibly a result of reading fatigue.

11 Dec 2012

Infinity announces new data from IPI-145 Phase 1 trial on advanced hematologic malignancies

Infinity Pharmaceuticals, Inc. today announced new data from its ongoing Phase 1, open-label, dose-escalation trial of IPI-145, the company's potent, oral inhibitor of phosphoinositide-3-kinase (PI3K)-delta and PI3K-gamma, in patients with advanced hematologic malignancies.

11 Dec 2012

Alpha arrestins may play a role in cell signaling that is crucial to new drug development

A newly found understanding of receptor signaling may have revealed a better way to design drugs. A study from Nationwide Children's Hospital suggests that a newly identified group of proteins, alpha arrestins, may play a role in cell signaling that is crucial to new drug development.

11 Dec 2012

Vodafone partners with GSK, GAVI to use, study mobile technology to improve vaccination rates

"British mobile phone group Vodafone and drug maker GlaxoSmithKline are joining forces on a novel project to increase childhood vaccination rates in Mozambique using text messaging," Reuters reports.

10 Dec 2012

FDA expands approved use of Janssen Biotech’s Zytiga to treat men with mCRPC

The U.S. Food and Drug Administration today expanded the approved use of Zytiga (abiraterone acetate) to treat men with late-stage (metastatic) castration-resistant prostate cancer prior to receiving chemotherapy.

10 Dec 2012

Brain scans could help scientists uncover mechanisms underlying mental fatigue

We all perhaps know the feeling of mental exhaustion, but what does it mean physiologically to have mental fatigue? A new study carried out using brain scans could help scientists uncover the neurobiological mechanisms underlying mental fatigue.

10 Dec 2012

Boston College professor to research into new drugs that can prevent onset of toxoplasmosis

The American Cancer Society has awarded a four-year, $720,000 grant to Boston College Associate Professor of Biology Marc-Jan Gubbels for research into potential new drugs that can prevent the onset of toxoplasmosis in cancer patients with weakened immune systems.

10 Dec 2012

Strong inverse association between caffeinated coffee intake and oral/pharyngeal cancer mortality

A new American Cancer Society study finds a strong inverse association between caffeinated coffee intake and oral/pharyngeal cancer mortality. The authors say people who drank more than four cups of caffeinated coffee per day were at about half the risk of death of these often fatal cancers compared to those who only occasionally or who never drank coffee.

10 Dec 2012

Janssen receives FDA approval for ZYTIGA to treat metastatic castration-resistant prostate cancer

Janssen announced today that the U.S. Food and Drug Administration (FDA) has approved a broader indication for the oral, once-daily medication ZYTIGA (abiraterone acetate).

10 Dec 2012

Viewpoints: Girding for a 'beloved' Medicare fight; Two views about health law's employer mandate; Doctors fear 'SGR cliff'

It's a shame that Republicans are playing into Mr. Obama's hands, negotiating in public among themselves, ... Tennessee Senator Bob Corker made the case for this strategic retreat on "Fox News Sunday," arguing that if Republicans raise tax rates as Mr. Obama wants, "the focus then shifts to entitlements and maybe it puts us in a place where we actually can do something that really saves the nation."

10 Dec 2012

Research News and Research

UNM study to understand why and how DNA repair mechanisms go awry in cancer cells

Combination of diagnostic tests can predict conversion from MCI to Alzheimer's

Isis, Biogen Idec partner to discover and develop antisense drugs against neuromuscular disorders

Study examines 3 main relative contributors to pedestrian death

New taxes, Medicaid expansion requests and health insurance portability make health law news

Study finds silent reading difficulties in glaucoma patients

Infinity announces new data from IPI-145 Phase 1 trial on advanced hematologic malignancies

Alpha arrestins may play a role in cell signaling that is crucial to new drug development

Vodafone partners with GSK, GAVI to use, study mobile technology to improve vaccination rates

FDA expands approved use of Janssen Biotech’s Zytiga to treat men with mCRPC

Brain scans could help scientists uncover mechanisms underlying mental fatigue

Boston College professor to research into new drugs that can prevent onset of toxoplasmosis

Strong inverse association between caffeinated coffee intake and oral/pharyngeal cancer mortality

Janssen receives FDA approval for ZYTIGA to treat metastatic castration-resistant prostate cancer

Viewpoints: Girding for a 'beloved' Medicare fight; Two views about health law's employer mandate; Doctors fear 'SGR cliff'

Childhood obesity: an interview with Professor Clodagh O’Gorman

Immune dysfunction pinpointed in developmental disorder

CYP2J2 implicated in preeclampsia

Meals on wheels reduces nursing home strain

Throat swabs should be included in S. aureus screening programs

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