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Children treated for soft tissue sarcomas at greater risk of second cancers

A new study has found that although children treated for soft tissue sarcomas are surviving longer than they did in the past, they have an increased risk for second cancers, especially when initial treatment combined radiation and chemotherapy. This is according to analysis of data from the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute.

27 Apr 2005

$Giving elderly people regular supplements of vitamin D and calcium to prevent secondary bone fractures is ineffective$

Giving elderly people regular supplements of vitamin D and calcium to prevent secondary bone fractures is ineffective

Elderly people who have osteoporosis have a high risk of bone fractures and those who previously had a fracture are at an increased risk of having another. Vitamin D and calcium, alone or in combination, are often recommended for the prevention of osteoporotic fractures.

27 Apr 2005

Common chest X-ray in the elderly can reveal osteoporosis

According to Canadian researchers undetected osteoporosis in the elderly might be discovered if chest X-rays that are done for other reasons were examined for fractures of the vertebrae.

27 Apr 2005

National clinical trial examines new option for kidney cancer patients

The trial, which opened last September, offers research subjects who qualify a new, targeted therapy in addition to standard immune therapy. The drug combination is being studied in a national Phase II clinical trial led by OHSU Cancer Institute researcher Christopher Ryan, M.D., through the Southwest Oncology Group, one of the largest clinical trial cooperative groups in the United States.

27 Apr 2005

Isotopes for society

The nucleus of an atom contains protons and neutrons. However, some atoms of the same chemical element can have varying numbers of neutrons, giving so-called isotopes of that element.

27 Apr 2005

High risk of second cancers in survivors of childhood soft tissue sarcomas

Children treated for soft tissue sarcomas have a significantly higher risk of developing subsequent cancers later in life, according to a new study. The study appears in the June 1, 2005 issue of CANCER, a peer-reviewed journal of the American Cancer Society, and indicates children treated with combined chemotherapy and radiation therapy, in particular, had greater risks of developing a new malignancy.

25 Apr 2005

Pattern of gene expression predicts multiple drug resistance, treatment failure in pediatric leukemia

The discovery of a specific pattern of gene expression linked to multiple-drug resistance of leukemic cells is giving researchers crucial information into why standard therapies fail to cure some children with acute lymphoblastic leukemia (ALL). This finding, from investigators at St. Jude Children’s Research Hospital, could lead to development of drugs that would overcome that resistance.

24 Apr 2005

Increasing benefit seen in novel drug AMN107, that treats Gleevec resistance

An investigational drug is producing powerful responses in patients resistant to Gleevec, the targeted therapy that helps most people diagnosed with chronic myeloid leukemia (CML), an international research team headed by investigators at The University of Texas M. D. Anderson Cancer Center is reporting.

23 Apr 2005

Patient with rare liver condition second ever to survive liver transplant after pregnancy

For Billi Tierney, 30, National Donate Life Month in April has a profound meaning. The first-time mother of Sycamore, Ill., was awaiting anxiously the arrival of her first baby. But she never thought that complications from her pregnancy were going to lead to a week in coma and the urgent need for a liver transplant. Tierney suffered from acute liver fatty of pregnancy, a rare, but serious condition of pregnancy in which there is an excessive accumulation of fat in the liver or liver cells.

23 Apr 2005

Stem cells from adults may cause cancer

Stem cells, often lauded as future cures for numerous diseases, are immature "master" cells that can be programmed to become many kinds of tissue, but experts have known for a long time that stem cells harvested from embryos can turn cancerous and have been linked to leukaemias and breast cancer.

23 Apr 2005

Enzyme that helps trigger the development of leukemia

Scientists at the University of North Carolina at Chapel Hill have identified an enzyme that helps trigger the development of leukemia, a cancer of blood cells.

21 Apr 2005

Gene expression pattern predicts multiple drug resistance

St. Jude Children's Research Hospital discovery of genetic links to multi-drug resistance gives clinicians new insight into the cause of treatment failure and suggests targets for novel anti-leukemic drugs

19 Apr 2005

Advance in genetics of cleft lip and palate

Cleft lip and/or palate remains one of the most common birth defects in the world. It occurs when the sides of the face fuse abnormally in a developing baby, resulting in a malformed lip and/or roof of the mouth.

12 Apr 2005

Innovation, competitive prices to underpin uptake of diagnostic ultrasound devices

Across Europe, the pricing of ultrasound systems is expected to be central to its uptake. In addition to being competitively priced, products with an emphasis on innovation, user-friendliness, mobility and compactness are also expected to appeal to end-users.

12 Apr 2005

Tissue engineering to grow bone, ligaments and cartilage

A future in which laboratory-grown organs and stimulated growth of muscle, bones and nerves could play a major role in treating medical conditions was revealed at a recent Tissue Engineering Symposium at Wake Forest University Baptist Medical Center.

11 Apr 2005

You need to do vigorous activity if you want to be lean

Adolescents who get daily vigorous physical activity tend to be leaner and fitter than their less active peers, researchers have shown.

7 Apr 2005

Osteoporosis drug reduces women's risk of mild cognitive impairment

A drug prescribed for the prevention of osteoporosis reduced women's risk of mild cognitive impairment by 33 percent in a worldwide clinical trial led by researchers at San Francisco VA Medical Center (SFVAMC).

6 Apr 2005

Organ donors must document their wishes

According to the results of a new survey by the Coalition on Donation, an alliance of national and local organ and tissue donation education groups, even though many Americans support organ and tissue donation and are willing to become donors themselves, many have not taken the steps required to ensure that their wishes will be carried out after their death.

5 Apr 2005

Potential therapeutic target for infertility and contraception

The multiple “litter” births of mice, versus the normal singleton pregnancy of humans, is due to defective processing in mice of a common mammalian protein called bone morphogenetic protein 15 (BMP-15), according to new research from the University of California, San Diego (UCSD) School of Medicine.

5 Apr 2005

Study suggests that eating onions might help prevent bone loss and osteoporosis

Besides adding flavor to food, onions also may be good for your bones. Researchers at the University of Bern in Switzerland have identified a compound in the popular vegetable that appears to decrease bone loss in laboratory studies using rat bone cells.

5 Apr 2005