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Tyk2 enzyme helps regulate obesity through differentiation of brown adipose tissue

Approximately 68 percent of U.S. adults are overweight or obese, according to the National Cancer Institute, which puts them at greater risk for developing cancer, cardiovascular disease, diabetes and a host of other chronic illnesses. But an international team of scientists led by Virginia Commonwealth University Massey Cancer Center researcher Andrew Larner, M.D., Ph.D., has successfully reversed obesity in mice by manipulating the production of an enzyme known as tyrosine-protein kinase-2 (Tyk2).

6 Dec 2012

Roundup: Florida health law battles take new turn; Oklahoma court rejects anti-abortion law; Calif. kids Medi-Cal dispute continues

Even in Florida, where Republican leaders led the legal battle against Obamacare, there's recognition now that the state has to act fast to comply with the new law. ... After Nov. 6, Gov. Rick Scott had a change in tone. "Gov. Mitt Romney did not win the election. So, it's not an option to repeal Obamacare," he said. "So, my goal now is to focus on what's good for our citizens." But Republicans are having trouble convincing Tea Party activists that the fight is over.

6 Dec 2012

Sickle cell disease trial completes phase 3 patient enrollment

Emmaus Medical, Inc., a specialty pharmaceutical and regenerative medicine company, today announced the completion of patient enrollment for its phase 3 clinical trial to study L-glutamine as a treatment for sickle cell disease.

5 Dec 2012

Obesity ramps up thoracic surgery costs

Obese patients have significantly increased operating times when undergoing lobectomy for primary lung cancer, show US study results.

5 Dec 2012

Old age no barrier to rectal resection

Advanced age alone should not rule out curative resection for rectal cancer, say the authors of a systematic review.

5 Dec 2012

Bipolar disorder prevalent in panic disorder patients

Bipolar disorder is common among Japanese patients with panic disorder, research shows.

5 Dec 2012

Nerve stimulation improves hand use in spinal cord injury patients

A method combining transcranial magnetic stimulation with electrical stimulation of peripheral nerves in the wrist temporarily improves hand use in spinal cord injury patients, show research findings published in Current Biology.

5 Dec 2012

‘Old’ erythrocytes little problem in noncardiac surgery

Erythrocytes that have been stored for several weeks before use may not cause problems in patients who receive transfusions during noncardiac surgery, a large retrospective analysis suggests.

5 Dec 2012

Vitamin D and women’s risk for multiple sclerosis

Women who have high vitamin D levels are at a decreased risk for developing multiple sclerosis, shows research.

5 Dec 2012

Surprising discovery about physical properties of cancer cells

A surprising discovery about the physical properties of cancer cells could help improve a new diagnostic approach - a liquid biopsy - that detects, measures, and evaluates cancer cells in blood.

5 Dec 2012

University of Chicago professor wins Manpei Suzuki International Prize for diabetes work

Graeme Ian Bell, PhD, the Louis Block Distinguished Service Professor of Medicine and Human Genetics and an investigator in the Kovler Diabetes Center at the University of Chicago, has been awarded the Manpei Suzuki International Prize for 2012 for his pioneering work in understanding the role of genetics in the diagnosis and treatment of diabetes.

5 Dec 2012

Study provides important data about fertility window of women with childhood cancer

This study provided important data about the fertility window of women who had suffered from childhood cancer and information concerning the associated risk factors, but did not confirm the greater risk of premature menopause (before the age of 40) that was reported by the American studies.

5 Dec 2012

New metabolic biomarkers can detect risk of illnesses in advance

One of the big challenges of biomedicine is understanding the origin of illnesses in order to improve early detection and significantly increase recovery rates, as well as being able to do what CNIO researchers call preventive molecular medicine, which consists of identifying those individuals who have a greater molecular risk of suffering certain pathologies in order to prevent them.

5 Dec 2012

Children with HIV more likely to develop atherosclerosis

Children with HIV have a 2.5 fold increased risk of atherosclerosis, according to research presented at EUROECHO and other Imaging Modalities 2012. Antiretroviral treatment, lipid lowering drugs and prevention with healthy lifestyles are needed to prevent early death from cardiovascular disease.

5 Dec 2012

Copper can prevent horizontal transmission of genes in antibiotic-resistant bacteria

New research from the University of Southampton has shown that copper can prevent horizontal transmission of genes, which has contributed to the increasing number of antibiotic-resistant infections worldwide.

5 Dec 2012

Smoking cessation support: an interview with Robyn Whittaker

Tobacco smoking involves a physiological addiction to nicotine for a lot of people. Quitting can cause some nasty symptoms due to the withdrawal of nicotine.

5 Dec 2012

Parental involvement prevents or limits alcohol and marijuana use by children

New research from North Carolina State University, Brigham Young University and the Pennsylvania State University finds that parental involvement is more important than the school environment when it comes to preventing or limiting alcohol and marijuana use by children.

5 Dec 2012

University of Kentucky creates new working model for EHR reporting of cancer cases

The University of Kentucky has created the nation's first working model for electronic health record (EHR) reporting of cancer cases to the state's cancer registry.

5 Dec 2012

BBC News examines HIV/AIDS in Iran

BBC News examines HIV/AIDS in Iran, writing, "In the 2000s, Iran became known as the region's leader in the fight against AIDS. Each year, the government allocates millions of dollars to prevent and manage the disease, and government-sponsored clinics across the country help battle it."

5 Dec 2012

Inserm prizes for medical research to be awarded on Dec. 3

The 2012 Inserm prizes for medical research will be awarded at a ceremony at the Coll-ge de France on Monday 3 December 2012. This year, the grand prize will be awarded to Philippe Sansonetti in the presence of Marisol Touraine, France's Minister of Social Affairs and Health, Genevi-ve Fioraso, France's Minister of Higher Education and Research, and Professor Andr- Syrota, Chairman and CEO of Inserm.

5 Dec 2012

Research News and Research

Tyk2 enzyme helps regulate obesity through differentiation of brown adipose tissue

Roundup: Florida health law battles take new turn; Oklahoma court rejects anti-abortion law; Calif. kids Medi-Cal dispute continues

Sickle cell disease trial completes phase 3 patient enrollment

Obesity ramps up thoracic surgery costs

Old age no barrier to rectal resection

Bipolar disorder prevalent in panic disorder patients

Nerve stimulation improves hand use in spinal cord injury patients

‘Old’ erythrocytes little problem in noncardiac surgery

Vitamin D and women’s risk for multiple sclerosis

Surprising discovery about physical properties of cancer cells

University of Chicago professor wins Manpei Suzuki International Prize for diabetes work

Study provides important data about fertility window of women with childhood cancer

New metabolic biomarkers can detect risk of illnesses in advance

Children with HIV more likely to develop atherosclerosis

Copper can prevent horizontal transmission of genes in antibiotic-resistant bacteria

Smoking cessation support: an interview with Robyn Whittaker

Parental involvement prevents or limits alcohol and marijuana use by children

University of Kentucky creates new working model for EHR reporting of cancer cases

BBC News examines HIV/AIDS in Iran

Inserm prizes for medical research to be awarded on Dec. 3

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