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Article highlights Asian-American children’s variable vulnerability to obesity

Asian-American children have been at low risk for being overweight or obese compared to other racial and ethnic groups in the U.S., but that may be changing. Yet as rates of overweight and obesity rise, the risk appears to vary depending on the Asian country of origin, according to an article in Childhood Obesity, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

30 Nov 2012

New detection method can identify genetic switches associated with breast cancer

Physicians may now be better at detecting breast cancer than ever before, but much more work remains to ensure accurate diagnosis is possible and especially to assess future risk. That's why researchers from Germany have been working to develop a new test of gene action to predict cancer risk both at first diagnosis and into the future.

30 Nov 2012

Aduro completes enrollment in CRS-207 and GVAX pancreas cancer vaccine Phase 2 trial

Aduro BioTech, Inc. announces completion of enrollment in the Phase 2 clinical trial of the sequential administration of two cancer vaccines, Aduro's CRS-207 and GVAX Pancreas Cancer Vaccine, in patients with metastatic pancreatic cancer.

30 Nov 2012

UBE3B gene linked to brain development disorder in children

Researchers have defined the gene responsible for a rare developmental disorder in children. The team showed that rare variation in a gene involved in brain development causes the disorder. This is the first time that this gene, UBE3B, has been linked to a disease.

30 Nov 2012

Scientists define key underlying process implicated in multiple sclerosis

Scientists at the Gladstone Institutes have defined for the first time a key underlying process implicated in multiple sclerosis (MS)-a disease that causes progressive and irreversible damage to nerve cells in the brain and spinal cord. This discovery offers new hope for the millions who suffer from this debilitating disease for which there is no cure.

30 Nov 2012

Epizyme to present data from DOT1L and EZH2 inhibitor programs at 54th ASH annual meeting

Epizyme, Inc., a biopharmaceutical company leading the creation of personalized therapeutics to treat patients with genetically defined cancers, today announced the presentation of data evaluating the preclinical safety and efficacy of two of the Company's novel, potent and selective small molecule inhibitors. These inhibitors individually target DOT1L and EZH2, members of a class of epigenic enzymes called histone methyltransferases (HMTs).

30 Nov 2012

Study: Only one third of MSM can easily access HIV services

A large-scale study of gay men and other men who have sex with men (MSM), conducted by the Global Forum on MSM & HIV (MSMGF), indicates that only one third of MSM can easily access condoms, lubricant, HIV testing, and HIV treatment.

29 Nov 2012

Alberta Children's Hospital performs first liver cell transplant in Calgary, Canada

A three-month-old Winnipeg girl has become the first patient in Canada to receive an experimental and potentially life-saving form of therapy to improve the function of her liver.

29 Nov 2012

LP-211 compound shows promise against Fragile X syndrome

A potential new therapeutic strategy for treating Fragile X syndrome is detailed in a new report appearing in the current issue of Biological Psychiatry, from researchers led by Dr. Lucia Ciranna at University of Catania in Italy.

29 Nov 2012

AstraZeneca receives FDA approval for Cometriq to treat medullary thyroid cancer

The U.S. Food and Drug Administration today approved Cometriq (cabozantinib) to treat medullary thyroid cancer that has spread to other parts of the body (metastasized).

29 Nov 2012

Methodist dietitian offers tips to prevent holiday weight gain

The holiday season is officially in full gear and with it comes the tempting Thanksgiving-to-New-Year's food fest. While research shows that the average person really only gains about a pound over the course of the holidays, it can still have a big cumulative effect on waistlines. That's because the extra weight usually doesn't come off the following year.

29 Nov 2012

Longer looks: Are 'pods' the solution to our long-term care crisis?; A Liver transplant in the nick of time; Pro-life activists and the abortion drop

In November 2006, when Clara Marshall began suffering from the effects of dementia, her family moved her into ... an assisted living home in Vancouver, Wash. ... just five months into her stay, Ms. Marshall, 81, was found dead in her room apparently strangled after getting her neck caught in side rails used to prevent her from rolling out of bed.

29 Nov 2012

Microscope system designed to acquire very low-light bioluminescence images introduced in North America by Olympus America

A benchtop commercial microscope system designed to acquire very low-light bioluminescence images has now been introduced in North America by Olympus America. The LV200 stand-alone microscope system is already being used to capture images of living cells and tissues by researchers in Europe and Japan.

From Evident Corporation - Life Sciences 29 Nov 2012

Study shows how PTPN22 variant linked with T1D influences susceptibility to autoimmunity

As part of their ongoing research on the role of genes in the development of type 1 diabetes, Joslin Diabetes Center scientists, in collaboration with scientists at the University of Würzburg, have demonstrated how a genetic variant associated with type 1 diabetes and other autoimmune diseases influences susceptibility to autoimmunity. The findings appear in the upcoming issue of Diabetes.

29 Nov 2012

Combination of blood test and whole-genome sequencing technology could screen cancers

Scientists at the Johns Hopkins Kimmel Cancer Center have combined the ability to detect cancer DNA in the blood with genome sequencing technology in a test that could be used to screen for cancers, monitor cancer patients for recurrence and find residual cancer left after surgery.

29 Nov 2012

Cautious Patient Foundation, SIDM partner to raise awareness of diagnostic errors

The Society to Improve Diagnosis in Medicine (SIDM) and the Cautious Patient Foundation announced today a collaboration to help patients avoid diagnostic errors in their own care. Diagnostic error, defined as wrong, missed or delayed medical diagnosis, occurs in 10 to 15% of diagnostic encounters, is the largest contributor to medical malpractice claims, and is responsible for 40,000 - 80,000 deaths per year in the United States.

29 Nov 2012

DLKI-DIO3 miRNA cluster suppresses spread of cancer from its primary site

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a group of what have been considered relatively minor regulators in the body that band together to suppress the spread of cancer from its primary site.

29 Nov 2012

University of Cincinnati to lead Belatacept Early Steroid withdrawal Trial

The University of Cincinnati will lead a $5.2 million national trial studying removal of both corticosteroids and common immunosuppression treatments from the post-transplant drug regimen for kidney transplant patients.

29 Nov 2012

States confront menu of Medicaid changes

A two-year payment hike for primary care doctors who treat Medicaid patients, called for by the health care law, might not happen without a struggle in Florida. Meanwhile, Kansas waits to hear back from the feds on its proposal to change Medicaid, and New Hampshire officials seek more money for their program.

29 Nov 2012

Infants of mothers born in the Philippines have low birth weights

Babies born in Ontario to mothers from the Philippines have significantly lower birth weights than those whose mothers were born in Canada or elsewhere in East Asia and are twice as likely to be classified as small for their gestational age, a new study has found.

29 Nov 2012

Research News and Research

Article highlights Asian-American children’s variable vulnerability to obesity

New detection method can identify genetic switches associated with breast cancer

Aduro completes enrollment in CRS-207 and GVAX pancreas cancer vaccine Phase 2 trial

UBE3B gene linked to brain development disorder in children

Scientists define key underlying process implicated in multiple sclerosis

Epizyme to present data from DOT1L and EZH2 inhibitor programs at 54th ASH annual meeting

Study: Only one third of MSM can easily access HIV services

Alberta Children's Hospital performs first liver cell transplant in Calgary, Canada

LP-211 compound shows promise against Fragile X syndrome

AstraZeneca receives FDA approval for Cometriq to treat medullary thyroid cancer

Methodist dietitian offers tips to prevent holiday weight gain

Longer looks: Are 'pods' the solution to our long-term care crisis?; A Liver transplant in the nick of time; Pro-life activists and the abortion drop

Microscope system designed to acquire very low-light bioluminescence images introduced in North America by Olympus America

Study shows how PTPN22 variant linked with T1D influences susceptibility to autoimmunity

Combination of blood test and whole-genome sequencing technology could screen cancers

Cautious Patient Foundation, SIDM partner to raise awareness of diagnostic errors

DLKI-DIO3 miRNA cluster suppresses spread of cancer from its primary site

University of Cincinnati to lead Belatacept Early Steroid withdrawal Trial

States confront menu of Medicaid changes

Infants of mothers born in the Philippines have low birth weights

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