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Researchers discover new cause of cytokine storm in COVID-19

As part of the COVID-19 International Research Team, researchers at the Johns Hopkins Kimmel Cancer Center, Children's Hospital of Philadelphia, the University of Pittsburgh and Weill Cornell Medicine discovered a novel cause of cytokine storm - the extreme inflammatory response associated with increased risk of death in COVID-19 infection.

2 Dec 2024

New study explores heart risks of cancer immunotherapy

A cancer therapy that prompts the body's immune defenses against viruses and bacteria to attack tumors can make patients more vulnerable to heart attack and stroke.

2 Dec 2024

Bacteria modify their ribosomes in response to the antibiotics

Bacteria modify their ribosomes when exposed to widely used antibiotics, according to research published today in Nature Communications. The subtle changes might be enough to alter the binding site of drug targets and constitute a possible new mechanism of antibiotic resistance.

29 Nov 2024

Advanced microscopy reveals how ribosomes attach to mRNA for protein synthesis

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA.

28 Nov 2024

Innovative annatto-based therapy shows promise for treating pediatric halitosis

A study by researchers working in Brazil shows that antimicrobial photodynamic therapy in which blue light targets annatto colorant is a feasible and effective option for treatment of halitosis in mouth-breathing children.

27 Nov 2024

PD-1 deficiency reveals the impact of checkpoint inhibition on B cell function

A multinational collaboration co-led by the Garvan Institute of Medical Research has uncovered a potential explanation for why some cancer patients receiving a type of immunotherapy called checkpoint inhibitors experience increased susceptibility to common infections.

27 Nov 2024

McMaster University develops fast and easy test for bacteria detection in fluids

A novel new test for bacteria in fluids makes it as easy as observing a color change to confirm the presence of disease-causing pathogens, promising much easier diagnostic tests and greater food safety.

26 Nov 2024

WHO and partners announce grants to boost pathogen genomic surveillance

The World Health Organization (WHO) and partners announced 10 projects that will receive almost US$ 2 million in grants to improve capacities in pathogen genomic surveillance.

26 Nov 2024

Study reveals how liver bile composition changes during enteric infections

Intestinal infections can change the composition of liver bile, leading to changes in immune function and gut bacteria, potentially helping fight off harmful bacteria .

26 Nov 2024

Unmasking the secrets of bacterial DNA supercoiling

Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Centre have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic target.

26 Nov 2024

Revolutionary strategy offers hope for type 1 diabetes treatment

Regenerative medicine holds the extraordinary promise that future patients in need of new cells, tissues or organs will no longer have to rely on donors. Organ shortages and cell type mismatches will become past problems, replaced by safe, on-demand options for anyone who needs a transplant.

25 Nov 2024

New AI model tailors phage treatment for resistant bacterial infections

With the rapid development of antibiotics in the 1930s, phage therapy – using viruses known as bacteriophages or phages to tackle bacterial infections – fell into oblivion.

25 Nov 2024

U.S. restaurants face scrutiny over antibiotic policies

U.S. restaurant chains face scrutiny for their role in antibiotic resistance, with Chipotle leading the way and others lagging behind in transparency and policy implementation.

25 Nov 2024

How breast cancer patients respond to tamoxifen may be linked to the gut microbiome

A new study has shown that variation in the microbiota of the human gut impacts the pharmacokinetics of tamoxifen and thus the effectiveness of the drug.

25 Nov 2024

Case Western Reserve secures $1.5 million NIH grant to improve bacterial vaginosis treatments

Bacterial vaginosis (BV), the most prevalent condition affecting the female reproductive system in women aged 15 to 44, is linked to such serious health risks as preterm birth, gynecological malignancies and sexually transmitted diseases.

25 Nov 2024

Freya Biosciences secures new investment to develop microbial immunotherapies for bacterial vaginosis

Freya Biosciences (Freya or the Company), a transatlantic biotech company specializing in women's health, today announces a $10.4 million strategic investment from the Bill & Melinda Gates Foundation (the foundation) with $1.4 million additional financing from current investor Export and Investment Fund of Denmark (EIFO).

25 Nov 2024

Probiotics shown to mitigate effects of toxic fire-retardant chemicals

Polybrominated diphenyl ethers, or PBDEs, are fire-retardant chemicals that are found everywhere - upholstery, carpets, curtains, electronics, and even infant products.

23 Nov 2024

New data highlights spread of carbapenem-resistant infections in Europe

Patients seeking treatment in hospital or other healthcare facilities can be particularly vulnerable for infections they acquire during their stay, especially if the infections are difficult to treat because they are resistant to commonly used drugs.

22 Nov 2024

Parkinson's disease drug disrupts the gut microbiome by inducing iron deficiency

In a groundbreaking new study, conducted within the framework of the FWF-funded Cluster of Excellence "Microbiomes drive Planetary Health", scientists from the University of Vienna, in collaboration with the University of Southampton, Aalborg University and Boston University, have revealed that the widely prescribed Parkinson's disease drug entacapone significantly disrupts the human gut microbiome by inducing iron deficiency.

22 Nov 2024

Wayne State's CEID calls for immediate community action on antimicrobial resistance

Wayne State University's Center for Emerging and Infectious Diseases (CEID) is launching its participation in World AMR Awareness Week with an urgent message: the growing threat of antimicrobial resistance requires immediate community action, so it is critical to educate, advocate, and act now.

22 Nov 2024