Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Prevention of post-menopausal osteoporosis in rats by sesame oil

Study demonstrates that daily supplementation with sesame oil in a rat model effectively prevents post-menopausal osteoporosis by maintaining serum estrogen and aromatase levels, suggesting its potential as a safer alternative to hormone replacement therapy.

4 Jan 2024

UT Southwestern discovers a two-step screening for heart failure prevention in patients with diabetes

A two-step screening protocol that combines clinical risk assessment with biomarker testing can more effectively identify which patients with Type 2 diabetes need medication to prevent heart failure, according to a study led by UT Southwestern Medical Center researchers.

3 Jan 2024

$4.9 million grant awarded to build EndO-trial consortium for improving the lives of Crohn's patients

Cleveland Clinic and the University of Western Ontario have been awarded a $4.9 million grant from Helmsley Charitable Trust to build a consortium to develop clinical trial outcome tools for patients with Crohn's disease and permanent ileostomy.

3 Jan 2024

Targeted ocular spectroscopy shines new light on retinal health

Study demonstrates the effectiveness of targeted ocular fluorescence spectroscopy for analyzing the eye fundus, offering potential advancements in diagnosing and treating eye diseases.

1 Jan 2024

Your unique microbiome may be used to improve and personalize your future medical experience

Study explores the potential of microbiomes in personalized medicine, focusing on diagnostics, precision therapy, and the challenges in implementing microbiome-based interventions.

27 Dec 2023

Increased β-amyloid accumulation may be linked to Alzheimer’s dementia risk in oldest of the old

A new study indicates that severity of amyloid deposition in the brain - not just age - may be key to determining who will benefit from new anti-amyloid therapies to delay the progression of Alzheimer's disease.

26 Dec 2023

Citrus supplement may ease knee swelling and pain after surgery

For patients undergoing total knee arthroplasty (TKA), treatment with diosmin – a flavonoid supplement derived from citrus fruits –reduced swelling of the knee and leg and some measures of associated pain can be achieved, reports a clinical trial in The Journal of Bone & Joint Surgery.

22 Dec 2023

Brain injury markers found in the blood months after COVID-19 infection

A new study published today (22 December 2023) in Nature Communications details that markers of brain injury are present in the blood many months after COVID-19 infection, despite inflammation blood tests being normal.

22 Dec 2023

Examining two serum biomarkers as early predictors of cognitive decline in women

Researchers from the University of Michigan have connected two blood biomarkers to changes in cognitive function in women in midlife, opening a potentially powerful path to noninvasive, earlier detection and interventions for Alzheimer’s disease and other dementias.

21 Dec 2023

A new test could save arthritis patients time, money, and pain. But will it be used?

Erinn Maury knew Remicade wasn't the right drug for Patti Schulte, a rheumatoid arthritis patient the physician saw at her Millersville, Maryland, practice. Schulte's swollen, painful joints hadn't responded to Enbrel or Humira, two drugs in the same class.

20 Dec 2023

Study reveals cytoglobin's pivotal role in cilia movement and organ positioning during development

Study reveals that cytoglobin (cygb2) plays a crucial role in regulating cilia motility and organ laterality during development, highlighting its importance in NO signaling and cilia function.

19 Dec 2023

AI-driven advancements in electronic skin technology promise revolution in health monitoring and diagnostics

Review discusses the integration of AI in developing next-generation e-skin, focusing on engineering challenges, signal processing, and health data analysis for applications in human-machine interfaces and disease diagnosis.

19 Dec 2023

Two proteins in the blood could predict dengue severity

Scientists and clinicians at Nanyang Technological University, Singapore (NTU Singapore) and the National Centre for Infectious Diseases (NCID) have identified two compounds - sST2 and suPAR - in the blood of dengue patients that could determine if a patient is at risk of severe dengue in the early phases of the disease.

18 Dec 2023

Researchers reveal a connection between cellular metabolism and depression, suicidal ideation

Major depressive disorder affects 16.1 million adults in the United States and costs $210 billion annually. While the primary symptoms of depression are psychological, scientists and doctors have come to understand that depression is a complex disease with physical effects throughout the body.

15 Dec 2023

New advance in the development of a test for early diagnosis of cancer

Blood cells reveal tumors in the body. Researchers at the Paul Scherrer Institute achieve an advance with the development of a test for early diagnosis of cancer.

14 Dec 2023

Association of genetically proxied PDE5 inhibition with measures of fertility, sexual behavior, and wellbeing

Researchers performed a two-sample Mendelian randomization analysis to investigate the associations between genetically proxied suppression of PDE5, a recognized pharmacological target for erectile dysfunction, fertility, subjective wellness, and sexual behavior.

14 Dec 2023

Epigenetic changes can contribute to the development of type 2 diabetes

Do epigenetic changes cause type 2 diabetes, or do the changes occur only after a person has become ill? A new study by researchers at Lund University provides increased support for the idea that epigenetic changes can cause type 2 diabetes.

13 Dec 2023

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Researchers performed a molecular analysis of neuroendocrine neoplasm (NEN) patient-derived tumor organoids (PDTOs) and their parental neoplasms.

13 Dec 2023

PharmaKure and Universiti Teknologi MARA (UiTM) announce partnership to advance research in Alzheimer’s Disease diagnosis

Research partnership aims to build strong pharma and academic collaborations in sharing data and clinical samples to develop biomarker-based diagnostics for Alzheimer’s Disease.

12 Dec 2023

Lymphatic fluid from surgical drains could inform more precise treatments for head and neck cancer

Lymphatic fluid from surgical drains, which is usually tossed in the trash, is a treasure in the hands of University of Pittsburgh and Washington University School of Medicine in St. Louis researchers who found that this liquid could inform more precise treatments for patients with head and neck cancer caused by human papillomavirus (HPV).

11 Dec 2023

Biomarker News and Research

Further Reading

Prevention of post-menopausal osteoporosis in rats by sesame oil

UT Southwestern discovers a two-step screening for heart failure prevention in patients with diabetes

$4.9 million grant awarded to build EndO-trial consortium for improving the lives of Crohn's patients

Targeted ocular spectroscopy shines new light on retinal health

Your unique microbiome may be used to improve and personalize your future medical experience

Increased β-amyloid accumulation may be linked to Alzheimer’s dementia risk in oldest of the old

Citrus supplement may ease knee swelling and pain after surgery

Brain injury markers found in the blood months after COVID-19 infection

Examining two serum biomarkers as early predictors of cognitive decline in women

A new test could save arthritis patients time, money, and pain. But will it be used?

Study reveals cytoglobin's pivotal role in cilia movement and organ positioning during development

AI-driven advancements in electronic skin technology promise revolution in health monitoring and diagnostics

Two proteins in the blood could predict dengue severity

Researchers reveal a connection between cellular metabolism and depression, suicidal ideation

New advance in the development of a test for early diagnosis of cancer

Association of genetically proxied PDE5 inhibition with measures of fertility, sexual behavior, and wellbeing

Epigenetic changes can contribute to the development of type 2 diabetes

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

PharmaKure and Universiti Teknologi MARA (UiTM) announce partnership to advance research in Alzheimer’s Disease diagnosis

Lymphatic fluid from surgical drains could inform more precise treatments for head and neck cancer

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo