Clinical Trial News and Research

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Snus withdrawal linked to weight gain and elevated blood pressure

Snus users who stopped using snus experienced higher blood pressure and gained weight. This has been shown by a research group at Linköping University, Sweden, in a study on 33 people, published in Harm Reduction Journal.

15 May 2025

Lung function decline in COPD patients accelerated by mucus plug persistence

Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in the United States, most often caused by cigarette smoking or long-term exposure to air pollutants.

14 May 2025

Physical function before treatment predicts response to daratumumab in multiple myeloma

How cancer patients relying on daratumumab feel physically before starting the therapy can predict how long they will live and how well they will respond to the anti- multiple myeloma (MM) drug, according to a new study published in the European Journal of Haematology.

14 May 2025

Mindfulness-based therapy offers new hope for people with persistent depression

Mindfulness-based therapy can offer significant relief for individuals who are still depressed after receiving treatment, according to a new clinical trial.

14 May 2025

Injecting medicine into amniotic fluid shows promise for treating genetic disorders

Injecting medicine into the amniotic fluid staves off progression of spinal muscular atrophy in utero.

14 May 2025

Once-daily oral treatment shows positive results in first human study for obesity treatment

A first-in-human study of an investigational once-daily oral treatment for obesity (SYNT-101) demonstrated positive preliminary data for the safe and effective redirection of nutrient absorption into the lower intestine, the weight loss and metabolic management mechanism behind gastric bypass surgery.

14 May 2025

WayBetter’s QuitBet app wins digital health award at Society of Behavioral Medicine conference

Erika Bloom, Ph.D., Director of Product and Research at WayBetter, won the Digital Health Tech Madness Champion Award at the Society of Behavioral Medicine’s (SBM) 46th Annual Meeting and Scientific Sessions in San Francisco, CA, USA, for her work on QuitBet, a groundbreaking app designed to support cigarette smoking cessation.

From Bedfont® Scientific Ltd 14 May 2025

Lean pork proven to enhance plant-forward diets for older adults

A newly published clinical feeding study out of South Dakota State University suggests that lean pork can play a central role in plant-forward dietary patterns for aging adults, offering high-quality protein, broad acceptability and alignment with current dietary guidance.

13 May 2025

New treatment approach boosts survival rates for patients with aggressive, inherited breast cancers

A new treatment approach significantly improves survival rates for patients with aggressive, inherited breast cancers, according to Cambridge researchers.

13 May 2025

Simple oral swab test could revolutionize IVF success rates

About 15 per cent of all couples of reproductive age are involuntarily childless. A major reason why so many need assisted reproduction is that nowadays more and more people are putting off starting a family.

13 May 2025

Online obesity clinic achieves clinical trial-level weight loss with lower semaglutide doses

New research being presented at this year's European Congress on Obesity (ECO 2025) has found that patients of an online obesity clinic achieved similar weight loss to that reported in clinical trials – but with less than half the medication.

12 May 2025

Testosterone use not linked to increased gynecological cancer risk in early years

Transmasculine and gender-diverse individuals who use testosterone are not at increased risk of gynecological cancer in the first years of hormone therapy.

12 May 2025

HER3 reemerges as a key driver of cancer progression and therapy resistance

A new publication shines a spotlight on HER3, a long-overlooked member of the ErbB receptor family, revealing its critical role in cancer progression and resistance to therapy.

12 May 2025

CAR-T cell therapy linked to brain fog in cancer patients

After treatment with CAR-T cells - immune cells engineered to attack cancer - patients sometimes tell their doctors they feel like they have "brain fog," or forgetfulness and difficulty concentrating.

12 May 2025

Hearing aids may help older adults combat social isolation

Providing hearing aids and advice on their use may preserve social connections that often wane as we age, a new study shows.

12 May 2025

Saving teeth through regeneration offers long-term benefits over implants

A major long-term study presented at EuroPerio11, the world's leading congress on gum health and implant dentistry by the European Federation of Periodontology (EFP), reveals that saving teeth with severe bone loss through periodontal regeneration (PR) offers benefits equal to - if not greater than - replacing them with dental implants or bridges.

12 May 2025

Tirzepatide outperforms semaglutide in weight loss clinical trial

Tirzepatide (trade name Zepbound) promoted greater weight loss in individuals with obesity than did semaglutide (trade name Wegovy) in a clinical trial that compared the safety and efficacy of the injectable drugs.

12 May 2025

Blocking LSD1 restores immune response in early oral cancer

Oral squamous cell carcinoma (OSCC) is a leading cause of cancer-related deaths, and early detection is key to improving patient outcomes. However, the mechanisms driving the transition from preneoplastic lesions to full-blown cancer are not well understood.

11 May 2025

Early menopause increases risk of fatty liver disease and metabolic disorders

Women who experience menopause before the age of 50 - and especially before the age of 45 - are more likely to develop fatty liver disease and its related metabolic risk factors within one year after menopause, according to research presented at the first Joint Congress between the European Society of Paediatric Endocrinology (ESPE) and the European Society of Endocrinology (ESE).

11 May 2025

Virtual nurse shows promise in promoting vaccinations

Can a virtual nurse persuade people to get vaccinated? Scientists from SWPS University have proven that it is possible. Finding new forms of informing people about vaccinations is particularly important for public health while some question their validity.

10 May 2025

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Clinical Trial News and Research

Snus withdrawal linked to weight gain and elevated blood pressure

Lung function decline in COPD patients accelerated by mucus plug persistence

Physical function before treatment predicts response to daratumumab in multiple myeloma

Mindfulness-based therapy offers new hope for people with persistent depression

Injecting medicine into amniotic fluid shows promise for treating genetic disorders

Once-daily oral treatment shows positive results in first human study for obesity treatment

WayBetter’s QuitBet app wins digital health award at Society of Behavioral Medicine conference

Lean pork proven to enhance plant-forward diets for older adults

New treatment approach boosts survival rates for patients with aggressive, inherited breast cancers

Simple oral swab test could revolutionize IVF success rates

Online obesity clinic achieves clinical trial-level weight loss with lower semaglutide doses

Testosterone use not linked to increased gynecological cancer risk in early years

HER3 reemerges as a key driver of cancer progression and therapy resistance

CAR-T cell therapy linked to brain fog in cancer patients

Hearing aids may help older adults combat social isolation

Saving teeth through regeneration offers long-term benefits over implants

Tirzepatide outperforms semaglutide in weight loss clinical trial

Blocking LSD1 restores immune response in early oral cancer

Early menopause increases risk of fatty liver disease and metabolic disorders

Virtual nurse shows promise in promoting vaccinations

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