Immune Response News and Research

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Study compares the immunogenicity and safety of two SARS-CoV-2 vaccines

The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019. Since then, extensive efforts have been made to develop and evaluate vaccines to combat the virus.

8 Nov 2023

Gamma delta T cells engineered to be more potent and long-lasting against cancer

UCLA scientists have developed a new method to engineer more powerful immune cells that can potentially be used for "off-the-shelf" cell therapy to treat challenging cancers.

8 Nov 2023

Human tissue model reveals diversity of bacterial strategies for urinary tract infections

The research, published today in Science Advances, is the first to use a sophisticated human tissue model to explore the interaction between host and pathogen for six common species that cause urinary tract infections.

8 Nov 2023

Gene expression in nearby healthy tissue may be a better predictor of lung cancer recurrence

Genetic information collected from seemingly healthy tissue near lung tumors may be a better predictor of whether cancer will come back after treatment than analysis of the tumors themselves, according to new research led by NYU Langone Health and its Perlmutter Cancer Center.

8 Nov 2023

Temperature plays crucial role in virus DNA release and infection

Researchers at Lund University, together with colleagues at the NIST Synchrotron Facility in the USA, have mapped on an atomic level what happens in a virus particle when the temperature is raised.

8 Nov 2023

Immune imprinting: The crux of waning COVID-19 booster effectiveness against new variants

The study in Nature Microbiology reviews the concept of immune imprinting and its influence on antibody responses to SARS-CoV-2, highlighting challenges for COVID-19 booster vaccination efficacy against emerging variants. Researchers suggest that understanding immune imprinting is crucial for developing vaccines that elicit broad and lasting immune protection.

7 Nov 2023

Proteomic study pinpoints potential biomarkers for long-COVID diagnosis and persistent health impacts

A two-year longitudinal study highlights proteomic changes in long-COVID patients, revealing potential biomarkers for diagnosis and shedding light on the persistent physiological challenges faced by survivors.

7 Nov 2023

New nasal vaccine for COVID-19 shows promise in animal studies

A team of University of Maryland researchers developed a nasal spray vaccine that delivers the SARS-CoV-2 spike protein into cells of the airway in mice and hamsters, triggering an immune response that significantly reduced infection and spread of COVID-19.

6 Nov 2023

Overcoming T-cell exhaustion: A new hope for CAR-T cell therapy

CAR-T cell therapy is a last hope for many patients with blood, bone marrow or lymph gland cancer when other treatments such as chemotherapy are unsuccessful.

6 Nov 2023

New study unveils Foxp3's role in regulatory T cell chromatin architecture

Regulatory T cells are specialized immune cells that suppress the immune response and prevent the body from attacking its own cells.

6 Nov 2023

Synthetic melanin nanoparticles boost wound healing and tissue repair in skin

In a recent study published in npj Regenerative Medicine, researchers discuss the ability of melanin nanoparticles to support wound recovery in mice. The effects at histological and gene levels were explored and confirmed on biomimetic models and human skin explants.

5 Nov 2023

UH researcher awarded $1.2 million grant to unravel mystery of Z-RNA

University of Houston Assistant Professor of Biology and Biochemistry Quentin Vicens has been awarded a $1.2 million grant from the National Institute of General Medical Sciences to unravel the mystery of Z-RNA – an enigmatic RNA structure within our cells that plays a critical role in immune response.

2 Nov 2023

Synthetic melanin cream heals skin damage and promotes repair

Imagine a skin cream that heals damage occurring throughout the day when your skin is exposed to sunlight or environmental toxins.

2 Nov 2023

LMU medical scientists discover new mechanism of alarmin release

LMU medical scientists have demonstrated that important pro-inflammatory mediators are released into the bloodstream through tiny pores in the cell membrane at a very early stage of the immune response.

2 Nov 2023

Unbiased proteomic analysis reveals fibroinflammatory landscape of the aging ovary

A new priority research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 20, entitled, "Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature."

31 Oct 2023

AI may help identify potential gonorrhea vaccine proteins

Gonorrhea, a sexually transmitted bacterial infection that affects more than 80 million people worldwide every year, has become resistant to almost all known antibiotics.

31 Oct 2023

Short-chain fatty acids produced by intestinal bacteria play role in dendritic cell elongation

Dendritic cells play a key role in the mammalian immune system. These cells are present throughout the human body and are known to capture foreign bodies, i.e., antigens, using extendable "arms" called dendrites.

30 Oct 2023

Redefining the battle against Alzheimer's with tau-focused treatments

Researchers explore the potential of tau-targeting therapies in treating Alzheimer's disease, focusing on immunotherapies and strategies to improve their efficacy. The study dives into the complex biology of tau proteins, their modifications, and how they can be targeted to halt the progression of Alzheimer's.

29 Oct 2023

Groundbreaking research advances understanding of how pathogens impact cancer

Viral infections are known to be a central cause of more than 10% of cancers worldwide. University of California researchers may have uncovered one of the key reasons why.

26 Oct 2023