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Urban outdoor aerobic training may have negative health effects

Training outside in an urban environment may not be as beneficial for a person’s health as they might hope, suggests research.

5 Nov 2012

Researchers develop new technique to predict enzymes known to accelerate diseases

Predicting how atherosclerosis, osteoporosis or cancer will progress or respond to drugs in individual patients is difficult.

3 Nov 2012

State of glycocalyx barrier indicates vascular risk in dialysis patients

The glycocalyx barrier – a mesh of proteoglycans and associated glycosaminoglycans present on vascular endothelium – is impaired in patients with renal failure, probably contributing to their predisposition to endothelial dysfunction and vascular disease, say researchers.

2 Nov 2012

Multiple sclerosis disease activity reduced by leukaemia drug, even when first-line treatment has failed

A drug which was originally developed to treat leukaemia and other cancers of the immune system offers substantial improvements over existing treatments in reducing relapse rates for people with multiple sclerosis (MS), even when they have not responded well to first-line treatment, according to the results of two phase 3 trials published Online First in The Lancet.

1 Nov 2012

Regular blood test may help predict survival in patients with Merkel cell carcinoma

A routine blood test may help predict survival in patients with an aggressive form of skin cancer known as Merkel cell carcinoma, according to new findings by Fox Chase Cancer Center researchers. The results will be presented on Wednesday, October 31 at the American Society for Radiation Oncology's 54th Annual Meeting.

1 Nov 2012

Physically active men produce better semen quality

A new study conducted by researchers at the University of Cordoba links moderate physical activity in males with better hormone levels and sperm characteristics that favour reproduction compared to sedentary men.

1 Nov 2012

Scientists solve mystery behind what triggers the herpes virus to become active again

The mere mention of the word "herpes" usually conjures negative images and stereotypes, but most people have been infected with some form of the virus. For most, a sore appears, heals and is forgotten, although the virus remains latent just waiting for the right circumstances to come back. Now, the mystery behind what triggers the virus to become active again is closer to being solved thanks to new research published in the Journal of Leukocyte Biology's November 2012 issue.

1 Nov 2012

‘Off the shelf’ stem cells show promise for perianal fistula

Expanded allogenic adipose-derived stem cells are effective for the treatment of perianal fistula in patients with Crohn’s disease, suggest the results of a phase I/II trial.

31 Oct 2012

Researchers decode software instructions that drive 3 different forms of acute lymphoblastic leukemia

30 Oct 2012

Scientists decode epigenetic programming of three virulent forms of acute lymphoblastic leukemia

A team of national and international researchers, led by Weill Cornell Medical College scientists, have decoded the key "software" instructions that drive three of the most virulent forms of acute lymphoblastic leukemia (ALL). They discovered ALL's "software" is encoded with epigenetic marks, chemical modifications of DNA and surrounding proteins, allowing the research team to identify new potential biomarkers and therapeutic targets.

29 Oct 2012

Sea water strengthens the body against viruses, low defences, bacteria and pathogens

Sea water therapy is a technique of cellular nutrition backed by more than 100 years of clinical use in hospitals, during which numerous studies have demonstrated its beneficial effects on patients' health.

29 Oct 2012

Improvements in rare cell isolation and common blood tests

At the Sixteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS) to be held Oct. 28-Nov. 1, in Okinawa, Japan, University of Cincinnati researchers will present four papers, including one detailing improvements in rare cell isolation and one detailing improvements, in terms of cost and time, of common blood tests.

29 Oct 2012

Pfizer receives FDA approval for Synribo to treat chronic myelogenous leukemia

The U.S. Food and Drug Administration today approved Synribo (omacetaxine mepesuccinate) to treat adults with chronic myelogenous leukemia (CML), a blood and bone marrow disease.

29 Oct 2012

mTor molecule plays a significant role in myeloid differentiation

University of Illinois cell and developmental Biology professor Fei Wang and colleagues have created a new technique to study how myeloids, a type of blood stem cell, become the white blood cells important for immune system defense against infections and tissue damage.

26 Oct 2012

CTCtrap can capture circulating tumour cells in cancer patients

The 7.5 millilitres of blood contained in a standard sample tube is not nearly enough to detect circulating tumour cells (CTCs) in the blood of patients with metastatic breast cancer, prostate cancer, or colorectal cancer with a high enough degree of reliability. These CTCs are the cause of metastases in cancer patients. If they can be effectively characterized, it is possible to arrive at a prognosis and to determine the most effective course of treatment.

26 Oct 2012

Pleiotrophin protein may be long-sought growth factor for blood stem cells

Duke Medicine researchers studying the interaction of blood stem cells and the niche where they reside have identified a protein that may be a long-sought growth factor for blood stem cells.

24 Oct 2012

UNM Cancer Center scientist to continue histone modification study

While every one of our cells contains all of our genetic information, each type of cell uses only specific parts of that information to make its proteins. Uncovering more about the mechanism that directs which particular pieces of genetic information the cell uses is the research focus of Mary Ann Osley, PhD, University of New Mexico Professor of Molecular Genetics and Microbiology and Co-Leader of the Cancer Biology and Biotechnology Program at the UNM Cancer Center.

24 Oct 2012

Pancreatic cancer risk linked to differences in telomeres' length in blood cells

A new study shows that a blood marker is linked to pancreatic cancer, according to a study published today by scientists at the University of Wisconsin Carbone Cancer Center and Mayo Clinic.

24 Oct 2012

Vascular cell generation could be used to treat vascular disorders

A study in mice has shown that large numbers of vascular endothelial cells can be generated from human amniotic fluid-derived cells.

23 Oct 2012

Study looks at DNA sequences for receptors in T lymphocytes

Our immune system must be tremendously complex to respond to the unending assault of viruses, bacteria and cancerous cells. One of the mechanisms used by the immune system to cope with the huge variety of possible threats is to randomly combine DNA segments for the production of receptors on lymphocytes - a type of white blood cell.

23 Oct 2012

Leukocyte News and Research

Urban outdoor aerobic training may have negative health effects

Researchers develop new technique to predict enzymes known to accelerate diseases

State of glycocalyx barrier indicates vascular risk in dialysis patients

Multiple sclerosis disease activity reduced by leukaemia drug, even when first-line treatment has failed

Regular blood test may help predict survival in patients with Merkel cell carcinoma

Physically active men produce better semen quality

Scientists solve mystery behind what triggers the herpes virus to become active again

‘Off the shelf’ stem cells show promise for perianal fistula

Researchers decode software instructions that drive 3 different forms of acute lymphoblastic leukemia

Scientists decode epigenetic programming of three virulent forms of acute lymphoblastic leukemia

Sea water strengthens the body against viruses, low defences, bacteria and pathogens

Improvements in rare cell isolation and common blood tests

Pfizer receives FDA approval for Synribo to treat chronic myelogenous leukemia

mTor molecule plays a significant role in myeloid differentiation

CTCtrap can capture circulating tumour cells in cancer patients

Pleiotrophin protein may be long-sought growth factor for blood stem cells

UNM Cancer Center scientist to continue histone modification study

Pancreatic cancer risk linked to differences in telomeres' length in blood cells

Vascular cell generation could be used to treat vascular disorders

Study looks at DNA sequences for receptors in T lymphocytes

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