Neurodegenerative Diseases News and Research

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Spark Therapeutics launches gene therapy clinical trial for late-onset Pompe disease

Pompe disease is a hereditary genetic disorder caused by a deficiency of acid alpha-glucosidase leading to build-up of glycogen in the lyosomes, which then causes cell damage in various tissues, in particular the heart, the muscles, the liver and the nervous system.

3 Feb 2021

UQ researchers discover how the brain 'tangles' in Alzheimer's disease and dementia

University of Queensland researchers have discovered a new 'seeding' process in brain cells that could be a cause of dementia and Alzheimer's disease.

2 Feb 2021

Protein alteration contributes to degeneration of neuronal populations in Huntington's disease

Protein alteration in the family of lamins causes several diseases, known as laminopathies, such as progeria or precocious aging.

1 Feb 2021

Study: Link between protein folding and misfolding can lead to the formation of amyloid fibers

Researchers from Osaka University have described the link between accurate protein folding and misfolding that can lead to the formation of amyloid fibers, which are implicated in neurodegenerative diseases

31 Jan 2021

Obesity may contribute toward neural tissue vulnerability, exacerbate Alzheimer's disease

New research from the University of Sheffield has found being overweight is an additional burden on brain health and it may exacerbate Alzheimer's disease.

29 Jan 2021

Scientists unravel how lipids distribute proteins within cells

An international team of scientists, coordinated by the Seville Institute of Biomedicine and the University of Seville has solved one of the hitherto unresolved enigmas of basic biology: how exactly do lipids distribute proteins within a cell? To do this, they used a new, completely innovative microscopy technology, which they applied to "mutant" cells they designed in their laboratory.

29 Jan 2021

Researchers use new imaging technique to understand motor deficits in ALS disease

An interdisciplinary team of the Institut national de la recherche scientifique (INRS) used an innovative imaging technique for a better understanding of motor deficits in Amyotrophic Lateral Sclerosis (ALS).

29 Jan 2021

Genetic changes in tumors can help predict the efficacy of immunotherapy drugs

Researchers at the Francis Crick Institute, the UCL Cancer Institute, and the Cancer Research UK Lung Cancer Centre of Excellence have identified genetic changes in tumors which could be used to predict if immunotherapy drugs would be effective in individual patients.

28 Jan 2021

Salk scientists receive $1.2 million from Larry L. Hillblom Foundation to study aging mechanisms

A collaborative team of Salk scientists led by Professor John Reynolds will receive $1.2 million over four years as part of a Network Grant from the Larry L. Hillblom Foundation to examine aging across the life span, including age-related neurodegenerative diseases such as Alzheimer's disease.

27 Jan 2021

New study provides both good and bad news about transient ischemic attacks

Study findings released Tuesday in the Journal of the American Medical Association (JAMA) hold both good news and bad news about transient ischemic attacks (TIAs), which are harbingers of subsequent strokes.

27 Jan 2021

£1.6 million grant awarded to advance development of MND drug candidate

Researchers from the University of Sheffield's Institute for Translational Neuroscience have been awarded a £1.6 million grant from the Medical Research Council.

26 Jan 2021

Promising nanobodies against COVID-19 produced by llamas

News-Medical speaks to Dr. David Brody about his latest research that involved discovering nanobodies produced by llamas that could help combat coronavirus.

25 Jan 2021

Deep sleep has restorative power to clear waste from the brain

A new Northwestern University study reaffirms the importance of getting a good night's sleep.

20 Jan 2021

Researchers focus on specific neurons that make reaching-and-grasping tasks possible

Research conducted at the Okinawa Institute of Science and Technology Graduate University, has looked at the importance of specific neurons for seemingly simple, day-to-day tasks that involve reaching for and grasping objects.

19 Jan 2021

Magnetic nanoparticles guide neurite growth in dopaminergic cells

Magnetic nanoparticles raise hopes of treatments for Parkinson’s.

19 Jan 2021

Researchers measure brain volume differences in HIV-infected individuals

Nearly 38 million people around the world are living with HIV, which, with access to treatment, has become a lifelong chronic condition. Understanding how infection changes the brain, especially in the context of aging, is increasingly important for improving both treatment and quality of life.

16 Jan 2021

Study may lead to novel synthetic drugs to combat bacterial infections

Researchers at the Technion – Israel Institute of Technology and EMBL Hamburg have discovered remarkable molecular properties of an antimicrobial peptide from the skin of the Australian toadlet. The discovery could inspire the development of novel synthetic drugs to combat bacterial infections.

15 Jan 2021

Researchers demonstrate great potential for blood test to detect, monitor Alzheimer's disease

In three recent publications in Molecular Psychiatry, Brain and JAMA Neurology researchers from the University of Gothenburg provide convincing evidence that an in-house developed blood test for Alzheimer's disease can detect the disease early and track its course, which has major implications for a potential use in clinical practice and treatment trials.

14 Jan 2021

Novel compound appears to protect myelin and nerve fibers

A compound developed at Oregon Health & Science University appears to protect nerve fibers and the fatty sheath, called myelin, that covers nerve cells in the brain and spinal cord.

13 Jan 2021

Researchers aim to improve cognitive performance, mobilize the brain's reserve mechanisms

Which neurobiological principles prevent us as humans from fully utilizing our own cognitive abilities and what are the performance limits of our brains?

8 Jan 2021

Neurodegenerative Diseases News and Research

Spark Therapeutics launches gene therapy clinical trial for late-onset Pompe disease

UQ researchers discover how the brain 'tangles' in Alzheimer's disease and dementia

Protein alteration contributes to degeneration of neuronal populations in Huntington's disease

Study: Link between protein folding and misfolding can lead to the formation of amyloid fibers

Obesity may contribute toward neural tissue vulnerability, exacerbate Alzheimer's disease

Scientists unravel how lipids distribute proteins within cells

Researchers use new imaging technique to understand motor deficits in ALS disease

Genetic changes in tumors can help predict the efficacy of immunotherapy drugs

Salk scientists receive $1.2 million from Larry L. Hillblom Foundation to study aging mechanisms

New study provides both good and bad news about transient ischemic attacks

£1.6 million grant awarded to advance development of MND drug candidate

Promising nanobodies against COVID-19 produced by llamas

Deep sleep has restorative power to clear waste from the brain

Researchers focus on specific neurons that make reaching-and-grasping tasks possible

Magnetic nanoparticles guide neurite growth in dopaminergic cells

Researchers measure brain volume differences in HIV-infected individuals

Study may lead to novel synthetic drugs to combat bacterial infections

Researchers demonstrate great potential for blood test to detect, monitor Alzheimer's disease

Novel compound appears to protect myelin and nerve fibers

Researchers aim to improve cognitive performance, mobilize the brain's reserve mechanisms

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