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Does influenza vaccination reduce death and vascular events in patients with heart failure?

Researchers conducted a placebo-controlled, double-blind clinical trial to assess whether influenza vaccination effectively reduced vascular events and mortality among patients with heart failure.

21 Nov 2022

FDA approves first-ever type 1 diabetes delaying drug Tzield (teplizumab-mzwv)

On November 17, 2022, the US Food and Drug Administration (FDA) approved a pathbreaking new drug called Tzield. This injectable formulation contains a combination of two drugs that could push back the onset of type 1 diabetes (T1D) in adults at stage 3 and children aged eight years or more at stage 2.

20 Nov 2022

Marijuana and e-cigarettes both increase risks of cardiac arrhythmias

In a recent study published in the Heart Rhythm journal, researchers at the University of California, San Francisco, assessed the relationship between different types of inhaled marijuana or tobacco product usage with ventricular and atrial arrhythmias.

17 Nov 2022

What is the prevalence of contraindications to Paxlovid among hospitalized COVID-19 patients?

Researchers examined the prevalence of contraindications to nirmatrelvir-ritonavir (Paxlovid) in hospitalized coronavirus disease 2019 (COVID-19) patients.

17 Nov 2022

PALS program effective in ensuring diverse representation in lupus clinical trials

The Lupus Research Alliance and its affiliate Lupus Therapeutics presented data at ACR Convergence 2022 with results showing the effectiveness of a pilot peer education program called the Patient Advocates for Lupus Studies (PALS), in increasing knowledge, perception, and willingness among people with Systemic Lupus Erythematosus (SLE) to participate in clinical trials.

14 Nov 2022

Oral deucravacitinib shows promise in patients with active lupus

Tyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus.

14 Nov 2022

First placebo-controlled long-term trial of anifrolumab shows positive results in patients with lupus

Type I interferon (IFN) is a powerful immune activator that is present at high levels in the majority of patients with lupus, an autoimmune disease. In Arthritis & Rheumatology, researchers report positive results from the first placebo-controlled long-term trial of anifrolumab - a human monoclonal antibody that targets the type I IFN receptor - in patients with lupus.

14 Nov 2022

Genicular nerve blocks provide short term pain relief for patients with knee osteoarthritis

Results from a recent clinical trial published by Wiley in Arthritis & Rheumatology demonstrate that patients with knee osteoarthritis experience short term pain relief from genicular nerve blocks - or locally injected anesthetics that block nerves around the knee joint.

13 Nov 2022

Study evaluates transcutaneous vagus nerve stimulation as treatment for long COVID-chronic fatigue

In a recent study posted to the medRxiv* server, researchers evaluated non-invasive transcutaneous vagus nerve stimulation [tVNS] as a treatment for long COVID-related chronic fatigue syndrome (CFS).

10 Nov 2022

Does fenofibrate improve clinical outcomes in patients with COVID-19?

Researchers assessed the effect of fenofibrate on acute COVID-19.

9 Nov 2022

Study: Fenofibrate not a useful strategy for decreasing COVID-19 severity

After showing promise in early laboratory research, the cholesterol-lowering drug fenofibrate had no significant effect on COVID-19 outcomes in a multicenter international randomized clinical trial led by Penn Medicine scientists.

8 Nov 2022

Long-term administration of IV iron benefits adults with heart failure and iron deficiency

Long-term treatment with iron administered intravenously improved symptoms and reduced recurrent hospitalizations among people with heart failure and iron deficiency, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Administering steroids during heart surgery does not improve post-operative outcomes in infants

The largest clinical trial ever conducted in infants younger than age 1 undergoing heart surgery with cardiopulmonary bypass found that administering steroids during surgery did not improve post-operative outcomes compared to placebo, according to preliminary late-breaking research to be presented at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

SGLT-2 inhibitors reduce cardiovascular risk among patients with chronic kidney disease

SGLT-2 inhibitors, a type of diabetes medicine, decreased cardiovascular risk among adults with chronic kidney disease, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Dietary supplements taken for 'heart health' unlikely to offer meaningful impact on cholesterol levels

Six widely used dietary supplements promoted for improving heart health did not effectively lower LDL or "bad" cholesterol in comparison to a common low-dose statin medication or placebo, according to late breaking science results presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

New medication lowers triglyceride levels, yet does not decrease cardiovascular risk in people with Type 2 diabetes

A new medication, pemafibrate, lowered triglyceride levels among adults with Type 2 diabetes yet did not decrease their cardiovascular risk, according to late-breaking science research presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Placebo News and Research

Does influenza vaccination reduce death and vascular events in patients with heart failure?

FDA approves first-ever type 1 diabetes delaying drug Tzield (teplizumab-mzwv)

Marijuana and e-cigarettes both increase risks of cardiac arrhythmias

What is the prevalence of contraindications to Paxlovid among hospitalized COVID-19 patients?

PALS program effective in ensuring diverse representation in lupus clinical trials

Oral deucravacitinib shows promise in patients with active lupus

First placebo-controlled long-term trial of anifrolumab shows positive results in patients with lupus

Genicular nerve blocks provide short term pain relief for patients with knee osteoarthritis

Study evaluates transcutaneous vagus nerve stimulation as treatment for long COVID-chronic fatigue

Does fenofibrate improve clinical outcomes in patients with COVID-19?

Study: Fenofibrate not a useful strategy for decreasing COVID-19 severity

Long-term administration of IV iron benefits adults with heart failure and iron deficiency

Administering steroids during heart surgery does not improve post-operative outcomes in infants

SGLT-2 inhibitors reduce cardiovascular risk among patients with chronic kidney disease

Dietary supplements taken for 'heart health' unlikely to offer meaningful impact on cholesterol levels

New medication lowers triglyceride levels, yet does not decrease cardiovascular risk in people with Type 2 diabetes

Rosuvastatin vastly superior to six common heart health supplements

New study provides more clarity about giving steroids during pediatric open-heart surgery

Novel drug lowers triglycerides, does not reduce cardiovascular events

Moderna's COVID-19 vaccine safe and effective in children 6 months to 5 years of age

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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