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Elevated levels of circulating proteins linked with protection against diabetic kidney disease

Elevated levels of three specific circulating proteins are associated with protection against kidney failure in diabetes, according to research from the Joslin Diabetes Center that will be published 30th June in Science Translational Medicine.

30 Jun 2021

New analysis links distinct patterns of genetic mutations with OCD

In the first analysis of its kind, researchers at Columbia University Vagelos College of Physicians and Surgeons and several other institutions have linked distinct patterns of genetic mutations with obsessive-compulsive disorder (OCD) in humans.

28 Jun 2021

City of Hope researchers identify how breast cancer cells acquire resistant traits

City of Hope, a world-renowned cancer research and treatment center, has identified how cancer cells in patients with early-stage breast cancer change and become resistant to hormone or combination therapies, according to a new study published in Nature Cancer.

24 Jun 2021

UCLA scientists discover how immune cells can be trained to fight potential threats

The body's immune cells naturally fight off viral and bacterial microbes and other invaders, but they can also be reprogrammed or "trained" to respond even more aggressively and potently to such threats, report UCLA scientists who have discovered the fundamental rule underlying this process in a particular class of cells.

24 Jun 2021

Genetic risk score predicts onset and severity of scoliosis in adolescents

In a study published in the Journal of Bone and Mineral Research, investigators developed and validated a genetic risk score for predicting the onset and severity of the most common type of scoliosis in adolescents--called adolescent idiopathic scoliosis (AIS).

23 Jun 2021

Bruker’s molecular phenomics research tools enable new insights into ‘long COVID’ and post-acute metabolic abnormalities

A clinical research collaboration on COVID-19 pheno-conversion and subsequent pheno-reversion has discovered transient and persistent systemic changes of the molecular signatures in patient blood samples three months after the acute COVID-19 disease phase.

From Bruker BioSpin Group 22 Jun 2021

Discovery provides new target to make melanomas more vulnerable to anti-cancer treatments

Hypoxia, or the inadequate oxygenation of a tissue, is a condition occurring frequently in all solid tumors such as melanoma skin cancer.

21 Jun 2021

KIYATEC’s test results accurately predict treatment response in recurrent high-grade glioma patients

KIYATEC, Inc. announced today the publication of new peer-reviewed data that establishes clinically meaningful prediction of patient-specific responses to standard of care therapy, prior to treatment, in newly diagnosed glioblastoma (GBM) and other high-grade glioma (HGG) patients.

18 Jun 2021

Novel drug class shows potential to treat cancer patients with faulty BRCA genes

Scientists have identified a new class of targeted cancer drugs that offer the potential to treat patients whose tumors have faulty copies of the BRCA cancer genes.

17 Jun 2021

Global blood centers join hands to develop more efficient, accurate blood typing technology

Blood centers from around the world have united to form an international collaboration with academic research institutions and a leading genomic array company, Thermo Fisher Scientific, to deliver a technology which promises to make the future of blood transfusion therapy more efficient, cost-effective, accurate, standardized, and safer.

17 Jun 2021

Precision medicine may lead to more effective treatments for ocular conditions

The most practical solution for drug delivery to the eyeball is topical, i.e. eye drops. However, a naturally occurring substance in tears actually can interact with the drug delivery system (DDS), hindering absorption of the drug and preventing it from getting into the cells it needs to target.

17 Jun 2021

UCLA wins $4.8 million NIH grant to develop methods for improving polygenic risk scores

UCLA Health will receive a $4.8 million grant from The National Institutes of Health to develop methods that will improve genetic risk estimates - polygenic risk scores - for specific diseases in people from diverse populations and mixed ancestries.

16 Jun 2021

Artificial intelligence for predicting TMB-H colorectal cancer from histopathological characteristics

Biomarkers are important determinants of appropriate and effective therapeutic approaches for various diseases including cancer.

14 Jun 2021

UCSF launches new initiative to propel the development of living therapeutics

UC San Francisco is launching a new initiative to propel the development of living therapeutics - a category of treatments broadly defined as human and microbial living cells that are selected, modified, or engineered to treat or cure disease - and bring them quickly to patients.

14 Jun 2021

Novel computer system can help inform future therapies for patients with inherited heart disease

An integrated, genomic computer system for precision cardiology has been created using clinical data that can help inform medical and surgical decisions to support future therapies for patients with inherited heart disease.

14 Jun 2021

Identifying genomic subtypes of pancreatic cancer from histology slides using AI-based tool

AP-HP Greater Paris University Hospitals, the leading European clinical trial center with the largest amount of healthcare data in France dedicated to research and Owkin, a startup pioneering Federated Learning and AI technologies for medical research and clinical development, announced the recent results of their ongoing strategic collaboration at ASCO 2021.

10 Jun 2021

Major anti-cancer protein released by neutrophils selectively kills tumor cells

A study published in the June 10, 2021 issue of Cell describes a remarkable new mechanism by which the body's own immune system can eliminate cancer cells without damaging host cells.

10 Jun 2021

QurAlis gears up for clinical development of therapeutic candidate, QRL-101

(BUSINESS WIRE)--QurAlis Corporation, a biotech company developing breakthrough precision medicines for ALS and other genetically validated neurodegenerative diseases, today announced the publication of an article in Cell Reports.

9 Jun 2021

Study aims to improve early screening for adverse childhood experiences by using precision medicine

Children's Hospital Los Angeles has been awarded a $2 million grant from the state of California to study a precision medicine approach to screening children for adverse childhood experiences.

3 Jun 2021

Predictive model detects patients who fit historical criteria for genetic testing

Patients who, perhaps unbeknownst to their health care providers, are in need of genetic testing for rare undiagnosed diseases can be identified en masse based on routine information in electronic health records (EHRs), a research team reported today in the journal Nature Medicine.

3 Jun 2021

Precision Medicine News and Research

Elevated levels of circulating proteins linked with protection against diabetic kidney disease

New analysis links distinct patterns of genetic mutations with OCD

City of Hope researchers identify how breast cancer cells acquire resistant traits

UCLA scientists discover how immune cells can be trained to fight potential threats

Genetic risk score predicts onset and severity of scoliosis in adolescents

Bruker’s molecular phenomics research tools enable new insights into ‘long COVID’ and post-acute metabolic abnormalities

Discovery provides new target to make melanomas more vulnerable to anti-cancer treatments

KIYATEC’s test results accurately predict treatment response in recurrent high-grade glioma patients

Novel drug class shows potential to treat cancer patients with faulty BRCA genes

Global blood centers join hands to develop more efficient, accurate blood typing technology

Precision medicine may lead to more effective treatments for ocular conditions

UCLA wins $4.8 million NIH grant to develop methods for improving polygenic risk scores

Artificial intelligence for predicting TMB-H colorectal cancer from histopathological characteristics

UCSF launches new initiative to propel the development of living therapeutics

Novel computer system can help inform future therapies for patients with inherited heart disease

Identifying genomic subtypes of pancreatic cancer from histology slides using AI-based tool

Major anti-cancer protein released by neutrophils selectively kills tumor cells

QurAlis gears up for clinical development of therapeutic candidate, QRL-101

Study aims to improve early screening for adverse childhood experiences by using precision medicine

Predictive model detects patients who fit historical criteria for genetic testing

Event guide: The 4th Precision Medicine in Inflammatory Bowel Disease Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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