Prophylaxis News and Research

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NIAID funds Nanotherapeutic for developing an inhaled version of the injectable antiviral drug

Nanotherapeutics, Inc., today announced that it has been awarded a $30.9 Million, 5-year contract from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), to develop an inhaled version of the injectable antiviral drug, cidofovir, for non-invasive, post-exposure prophylaxis and treatment of the Category A bioterrorism agent smallpox (Variola major).

25 Aug 2009

FDA approves Helixate FS for routine prophylaxis in children with hemophilia A

CSL Behring announced today that Helixate® FS, Antihemophilic Factor (Recombinant), has been approved by the U.S. Food and Drug Administration (FDA) for routine prophylaxis in children with hemophilia A who are 16 years old or younger and do not have pre-existing joint damage.

17 Aug 2009

Antiretroviral syrup for babies, mothers safely reduces HIV transmission

Giving daily antiretroviral syrup to breastfeeding infants or treating their HIV-infected mothers with highly active antiretroviral drugs is safe and effective in preventing mother-to-child HIV transmission through breast milk, a study led by University of North Carolina at Chapel Hill investigators has found.

27 Jul 2009

Prevention, vaccines addressed at IAS conference

During the 5th International AIDS Society (IAS) Conference on HIV Pathogenesis, Treatment and Prevention meeting in Cape Town, South Africa, scientists "renewed the call for more immediate and urgent effort to be directed towards HIV prevention amid the dominance of treatment interventions and the world-wide search for a quick fix vaccine, which many agree, is years away," Health-e/allAfrica.com reports (Thom, 7/22).

22 Jul 2009

MedImmune funds study on RSV disease among premature infants

MedImmune continues to advance its commitment to pediatric research with today's announcement of the first observational prospective study designed to assess the burden of respiratory syncytial virus (RSV) among preterm infants 32-to-35 weeks gestational age (GA) in outpatient settings during their first year of life.

30 Jun 2009

Piecing together the HIV prevention puzzle

"It's an exciting time in HIV prevention research. We will see results from a number of critically important HIV prevention research trials this year, as well as see the start of new trials around the world that will yield important answers in the years to come," said Mitchell Warren, AVAC executive director, at the release of AVAC's 13th annual report of the field.

18 May 2009

Vietnamese HIV/AIDS Department announces funding for prevention efforts

Vietnamese officials announced recently that about 678 billion dong, or about $38.7 million, will be allocated for HIV/AIDS prevention efforts in the country in 2009, the VNA/VietnamPlus.com reports.

14 May 2009

Warning on fraudulent 2009 H1N1 influenza products

The U.S. Food and Drug Administration and the Federal Trade Commission are alerting the public to be wary of Internet sites and other promotions for products that claim to diagnose, prevent, mitigate, treat or cure the 2009 H1N1 influenza virus.

3 May 2009

A negative mGluR5 allosteric modulator shows efficacy in treating acute migraine attacks

When migraine strikes, because of severe pain, often accompanied by nausea and sensitivity to light and sound, sufferers are effectively disabled for up to 72 hours.

30 Apr 2009

Tolera Therapeutics granted orphan drug status for organ transplant rejection lead candidate drug

Tolera Therapeutics, Inc., was granted orphan drug status by the United States Food and Drug Administration (FDA) for its initial lead candidate, TOL101, for prophylaxis of acute rejection of solid organ transplantation.

12 Apr 2009

Inter Press service examines research into PrEP

Inter Press Service last week examined how researchers are investigating the use of antiretroviral drugs as a possible method of pre-exposure prophylaxis. AIDS Vaccine Advocacy Coalition's Executive Director Mitchell Warren recently said that such efforts are "a pivotal moment in HIV/AIDS research."

6 Apr 2009

Hair helps predict HIV/AIDS treatment success

UCSF researchers have found that examining levels of antiretroviral drugs in hair samples taken from HIV patients on therapy strongly predicts treatment success.

2 Apr 2009

Philadelphia Inquirer examines developments, ethics in microbicide research

The Philadelphia Inquirer on Monday examined issues surrounding microbicide research, including recent developments and ethical issues. Philadelphia Inquirer examines developments, ethics in microbicide research

24 Mar 2009

NEJM Letters respond to recent studies on malaria vaccines, treatments

The New England Journal of Medicine in its March 19 issue featured a letter to the editor written in response to a study published in its Dec. 11 issue reporting the results of the RTS,S/AS01E malaria vaccine trial.

23 Mar 2009

Lethal risks associated with preparing dog meat

Eating dog meat is common in many Asian countries, but research conducted as part of the South East Asian Infectious Diseases Clinical Research Network has discovered a potentially lethal risk associated with preparing dog meat: rabies.

16 Mar 2009

Genes more important in cleft lip and palate than previously thought

Comparing 500,000 snippets of human DNA put scientists from the University of Bonn on the right track.

8 Mar 2009

European Commission and US FDA approve intravenous formulation of temozolomide

Schering-Plough Corporation (NYSE:SGP) today announced that the European Commission and the US FDA both approved the intravenous (IV) formulation of temozolomide as an alternative to the already approved oral form of the drug.

5 Mar 2009

Hair helps predicts HIV antiretroviral treatment success

UCSF researchers have found that examining levels of antiretroviral drugs in hair samples taken from HIV patients on therapy strongly predicts treatment success.

3 Mar 2009

Influenza A's resistance to drug Tamiflu increasing

Influenza A viruses (H1N1 subtype) that are resistant to the drug oseltamivir circulated widely in the U.S. during the 2007-2008 influenza season, with an even higher prevalence of drug resistance during the current 2008-2009 influenza season, according to a study to be published in the March 11 issue of JAMA, the Journal of the American Medical Association.

2 Mar 2009

A new monkey model for HIV

By altering just one gene in HIV-1, scientists have succeeded in infecting pig-tailed macaque monkeys with a human version of the virus that has until now been impossible to study directly in animals.

2 Mar 2009