Rheumatology News and Research

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Rheumatology is a sub-specialty in internal medicine and pediatrics, devoted to the diagnosis and therapy of rheumatic diseases. Rheumatologists mainly deal with clinical problems involving joints, soft tissues and allied conditions of connective tissues.

Real life experience of defibrillators lives up to clinical trial expectations

There is no significant difference in survival between clinical trial patients who receive an implantable cardioverter and clinical registry patients who receive a primary prevention ICD, researchers suggest.

7 Jan 2013

Root of socioeconomic impact on hypertension pinpointed

People who earn a low wage have a greater risk for hypertension than their counterparts with a higher income, especially women and those aged 25–44 years, research suggests.

7 Jan 2013

EPIRUS’ BOW-015 achieves bioequivalence to Remicade in a single dose comparator trial

EPIRUS Biopharmaceuticals, Inc., formerly known as fourteen22 Inc, announced that its lead asset, BOW-015, achieved bioequivalence to Remicade in a single dose comparator trial.

3 Jan 2013

Small numbers of ANA- and RP-negative patients with systemic sclerosis

There exists a very small subgroup of patients with systemic sclerosis who lack circulating antinuclear antibodies and who do not have Raynaud's phenomenon, research shows.

31 Dec 2012

Weight gain after adolescence has repercussions for hypertension

Individuals who gain weight in adulthood as well as those who are overweight in adolescence and adulthood are at increased risk for hypertension, research suggests.

31 Dec 2012

Proteins detected in urine may enable diagnosis of Kawasaki disease

A set of proteins detected in urine by researchers at Boston Children's Hospital may prove to be the first biomarkers for Kawasaki disease, an uncommon but increasingly prevalent disease which causes inflammation of blood vessels that can lead to enlarged coronary arteries and even heart attacks in some children.

20 Dec 2012

Men with fibromyalgia symptoms less likely to receive diagnostic tests

Fibromyalgia is a complex illness to diagnose and to treat. There is not yet a diagnostic test to establish that someone has it, there is no cure and many fibromyalgia symptoms -- pain, fatigue, problems sleeping and memory and mood issues -- can overlap with or get mistaken for other conditions. A new Mayo Clinic study suggests that many people who have fibromyalgia, especially men, are going undiagnosed.

20 Dec 2012

Osteoporosis screening: an interview with Professor Cyrus Cooper

Osteoporosis is defined as a reduction in bone mass coupled with micro-architectural deterioration of bone tissue which predisposes to fractures. Osteoporosis manifests through an increased risk of fracture, and age-related fractures are a major public health problem.

17 Dec 2012

SLU researchers to study physiological and biochemical functions in lupus

Two researchers at Saint Louis University's division of rheumatology in the department of internal medicine have been awarded a $1.8 million NIH grant to study the physiological and biochemical functions in lupus, an autoimmune disease, and develop possible new medications for its treatment.

14 Dec 2012

Top-line results from AstraZeneca’s fostamatinib Phase IIb monotherapy study on RA

AstraZeneca today announced top-line results of OSKIRA-4, a Phase IIb monotherapy study of fostamatinib, the first kinase inhibitor with selectivity for SYK (spleen tyrosine kinase) in development as an oral treatment for rheumatoid arthritis (RA).

13 Dec 2012

Health systems must be more ‘adherence-friendly’

Heath system strategies must be appropriately designed to help narrow persistent racial/ethnic gaps in the use of antihypertensive therapy, say researchers.

13 Dec 2012

Heartbeat Experts announces increased revenue and expanded clients in emerging markets

Heartbeat Experts, the global leader in stakeholder management solutions for the life sciences industry, announced today increased revenue and expanded clients across Brazil, Russia, China, India and Korea. Heartbeat Experts' reported combined revenue from these markets grew 50% in the third quarter of 2012.

13 Dec 2012

Takeda, Lundbeck announce FDA acceptance of vortioxetine NDA submission

Takeda Global Research & Development Center, Inc., (Takeda) and H. Lundbeck A/S (Lundbeck) jointly announced today that the U.S. Food and Drug Administration (FDA) has accepted for filing their submission of a New Drug Application (NDA) for vortioxetine for the treatment of major depressive disorder (MDD) in adult patients.

13 Dec 2012

CYP2J2 implicated in preeclampsia

Study findings suggest that uteroplacental cytochrome P450 subfamily 2J polypeptide 2 overexpression contributes to preeclampsia.

10 Dec 2012

$Orthoses improve pain, balance in fracture-prone elderly$

Orthoses improve pain, balance in fracture-prone elderly

Short-term use of foot orthoses reduces pain and disability in elderly women with osteoporosis, results of a randomized clinical trial indicate.

6 Dec 2012

Vasculitis and the metabolic syndrome frequently co-exist

The metabolic syndrome is significantly more common in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis than healthy individuals, researchers have found.

3 Dec 2012

Structured hypertension care: VIPER lacks real bite

An intensive structured care program for hypertension management in primary care leads to some improvements in blood pressure control, results from the VIPER-BP trial show.

3 Dec 2012

Report finds low infection rate for hip replacement or revision procedures at HSS

For the fourth year in a row, Hospital for Special Surgery has an infection rate that is significantly lower than the New York State average for hip replacement or revision surgeries, according to the 2011 report on hospital infection rates just released by the State Department of Health.

1 Dec 2012

New insights into relationship between autoimmunity and brain function

A study published in the current issue of Psychotherapy and Psychosomatics by a group of French investigators of the University of Paris unravels new insights as to the relationship between autoimmunity and brain function.

30 Nov 2012

Scientists identify two genes involved in establishing neuronal circuits required for breathing

Scientists at NYU Langone Medical Center have identified two genes involved in establishing the neuronal circuits required for breathing. They report their findings in a study published in the December issue of Nature Neuroscience.

30 Nov 2012