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Study: Less than half of clinical trials report race/ethnicity data

Clinical trials represent one the largest investments of collective resources in science. These studies, which recruit participants and rigorously evaluate new interventions and therapeutics, aim to advance scientific knowledge and improve patient treatment.

11 Apr 2022

Challenges, unmet needs and future opportunities in COVID-19 therapeutics

In a recent article published in the journal Proceedings of the National Academy of Sciences (PNAS), researchers reviewed the present-day therapeutic landscape of coronavirus disease 2019 (COVID-19) and addressed future opportunities to overcome challenges that hinder drug development and improve the global preparedness for future pandemics.

10 Apr 2022

Nanomedicine for treating life-threatening brain tumors

Innovation Center of NanoMedicine (Director General: Prof. Kazunori Kataoka) has announced that Dr. Sabina Quader et al. published a review article focusing on the recent nanomedicines for brain cancers on Advanced Drug Delivery Review in this March.

8 Apr 2022

NHLBI researchers support multiple programs to address pregnancy-related health disparities

During Black Maternal Health Week, April 11-17, and in preparation for Women's Health Month in May, researchers are raising awareness about pregnancy-related complications that disproportionately affect Black people.

7 Apr 2022

High-throughput screening assay could identify new prostate cancer drugs

A novel high-throughput screening assay is designed to identify inhibitors of the androgen receptor, which plays a critical role in the progression of prostate cancer.

6 Apr 2022

Study shows link between language status and health outcomes during COVID-19 hospitalizations

The language status of patients hospitalized for COVID-19 may significantly impact health outcomes during their admission, as non-English speaking individuals were found to have 35 percent greater odds of dying or requiring intensive care unit (ICU) support during the earliest phase of the pandemic compared to English-speaking patients, according to a study by Mass General Brigham (MGB).

6 Apr 2022

Virtual reality psychological therapy shown to work well for patients with mental health problems

In a landmark development, psychological therapy has been automated in virtual reality. With the user guided by a virtual coach, there is no need for a real-life therapist, meaning the treatment can reach many more patients.

6 Apr 2022

New tissue engineered neuromuscular interfaces “babysit” the muscles to improve functional recovery

Researchers engineered the first injectable microtissue containing motor and sensory neurons encased in protective tissue, called tissue engineered neuromuscular interfaces (TE-NMIs).

5 Apr 2022

Evidence SARS-CoV-2 undergoes ADAR-mediated A-to-I RNA editing in human cells

In a recent study published in the journal PLOS Genetics, researchers explored severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) ribonucleic acid (RNA) editing in host cells.

4 Apr 2022

TMPRSS2 inhibitor found to be a novel and effective therapeutic option against pan-variant SARS-CoV-2 infections

Researchers assessed the efficacy of TMPRSS2 against SARS-CoV-2 variants of concern Alpha, Beta, Gamma, and Delta, in mice and human lung cells.

1 Apr 2022

GE-led team uses ultrasound to prevent or reverse Type-2 diabetes in preclinical models

Are we moving closer to the day when diabetes is no longer monitored and managed with blood sugar tests, insulin injections and drug treatments? A GE Research-led team, which includes The Feinstein Institutes for Medical Research, UCLA Samueli School of Engineering, Yale School of Medicine, and Albany Medical College, has demonstrated the ability to prevent or reverse the onset of diabetes in studies of three different preclinical model systems.

31 Mar 2022

3D Printing Testicular Cells to Treat Infertility

In this interview, we speak to Dr. Ryan Flannigan about his latest research that involved the 3D printing of sperm cells to help treat male infertility.

31 Mar 2022

A summary of SARS-CoV-2 RNA-protein interactome studies

A new study summarized the importance of SARS-CoV-2 ribonucleic acid protein interactomes in the study of RNA viruses.

30 Mar 2022

Discovering a new possible treatment for COVID-19

In this interview, we speak to Dr. Ahmed G. Ibrahim about his latest research that has discovered a new possible treatment for COVID-19.

30 Mar 2022

Engineering rotavirus-based vaccine vectors expressing SARS-CoV-2 spike epitopes

Researchers proposed rotavirus-based vaccine vectors with the potential for developing polyvalent vaccines targeting multiple enteric viruses, including SARS-CoV-2.

30 Mar 2022

Music program teaches deaf and hard-of-hearing children to better understand sounds

A 12-week music program is helping deaf and hard-of-hearing children learn to optimize their hearing aids and cochlear implants, by teaching them to better understand the sounds they detect.

30 Mar 2022

SARS-CoV-2 nucleocapsid protein linked to COVID-19 severity

The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes respiratory coronavirus disease 2019 (COVID-19) triggered an unprecedented public health emergency. Human mobility patterns were fundamental to the spread of SARS-CoV-2 globally. The situation is particularly acute in a country like Saudi Arabia, which has seen more than 750,000 cases and over 9,000 deaths as of March 30th, 2022.

29 Mar 2022

Sino Biological and Ainnocence Partner to Offer Next-Generation Antibody Development CRO Services

Sino Biological is pleased to announce a CRO services partnership with Ainnocence, Inc. of San Jose, California.

From Sino Biological Inc. 24 Mar 2022

Researchers aim to study the underlying pathophysiology of diastolic heart failure

Of the estimated five million patients in the U.S. diagnosed with heart failure annually, nearly half will have heart failure with preserved ejection fraction (HFpEF). Also known as diastolic heart failure, HFpEF occurs when the heart's lower left chamber loses its ability to relax and fill up with enough blood in between in each heartbeat.

23 Mar 2022

CHOP and Penn Medicine join hands to address environmental hazards and protect vulnerable children

Children in the Greater Philadelphia area face a number of environmental threats to their health, including lead poisoning, asthma from air pollution, and exposure to endocrine disrupting chemicals.

21 Mar 2022

Translation News and Research

Study: Less than half of clinical trials report race/ethnicity data

Challenges, unmet needs and future opportunities in COVID-19 therapeutics

Nanomedicine for treating life-threatening brain tumors

NHLBI researchers support multiple programs to address pregnancy-related health disparities

High-throughput screening assay could identify new prostate cancer drugs

Study shows link between language status and health outcomes during COVID-19 hospitalizations

Virtual reality psychological therapy shown to work well for patients with mental health problems

New tissue engineered neuromuscular interfaces “babysit” the muscles to improve functional recovery

Evidence SARS-CoV-2 undergoes ADAR-mediated A-to-I RNA editing in human cells

TMPRSS2 inhibitor found to be a novel and effective therapeutic option against pan-variant SARS-CoV-2 infections

GE-led team uses ultrasound to prevent or reverse Type-2 diabetes in preclinical models

3D Printing Testicular Cells to Treat Infertility

A summary of SARS-CoV-2 RNA-protein interactome studies

Discovering a new possible treatment for COVID-19

Engineering rotavirus-based vaccine vectors expressing SARS-CoV-2 spike epitopes

Music program teaches deaf and hard-of-hearing children to better understand sounds

SARS-CoV-2 nucleocapsid protein linked to COVID-19 severity

Sino Biological and Ainnocence Partner to Offer Next-Generation Antibody Development CRO Services

Researchers aim to study the underlying pathophysiology of diastolic heart failure

CHOP and Penn Medicine join hands to address environmental hazards and protect vulnerable children

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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