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Medical device innovations - fabricating the future

Two large pieces of metal lie on the floor of what looks like a mini-factory in the Cleveland Clinic’s Lerner Research Institute. The whirring machinery here stamps out prototypes of medical devices imagined by clinicians and researchers to help with diagnostic testing or surgical procedures.

9 Jan 2005

Promising new evidence for the optimal use of biologic therapies for rheumatoid arthritis

A major cause of pain and disability, rheumatoid arthritis (RA) is also potentially the most treatable form of chronic arthritis. Researchers, doctors, and patients agree that a group of drugs called disease-modifying antirheumatic drugs (DMARDs) can effectively reduce joint pain and stiffness.

7 Jan 2005

Strong association between high levels of hyaluronic acid and severe osteoarthritis

A chronic degenerative joint disease, osteoarthritis (OA) is a common cause of pain and disability among older Americans. OA of the knee affects up to 6 percent of the older population, while OA of the hip affects about another 3 percent. While treatments vary, there is hope that early intervention – before joint destruction can be clearly seen and measured on an X-ray image-will improve outcomes.

7 Jan 2005

Potential cure for lymphoma in HIV patients

Stem cell transplants have become the standard of care for patients with relapsed lymphoma, but not for patients who suffer from both this disease and HIV.

7 Jan 2005

Stem cells from umbilical cord blood effectively treated heart attacks

When injected into rats' hearts soon after a heart attack, stem cells taken from human umbilical cord blood (HUCB) greatly reduced the size of heart damage and restored pumping function to near normal. This improvement occurred without the need for drugs to prevent the rats' immune system from rejecting the human cells.

5 Jan 2005

Calcium intake contributing factor in formation of kidney stones

Individuals with either calcium oxalate or calcium phosphate kidney stones should not take extra calcium on their own as suggested by previous research, but should check with their doctors to determine the dietary guidelines that work best for them, researchers at UT Southwestern Medical Center at Dallas have found.

4 Jan 2005

Signaling molecule involved in osteoarthritis identified

Using naturally-occurring mutant mice with a defective collagen gene, scientists at Harvard have identified a signaling molecule involved in one of the most common causes of disability among the elderly in the United States, osteoarthritis.

4 Jan 2005

Least forceful way to deliver a baby whose shoulders are stuck in the birth canal

Johns Hopkins researchers, using a novel birthing simulator designed by biomedical engineering faculty, staff and students at the University, have identified what may be the least forceful way to deliver a baby whose shoulders are stuck in the birth canal.

3 Jan 2005

FDA clearance for laser contact bone removal

Lumenis Ltd., and OpusDent Ltd., its dental laser division, announced the FDA clearance of the OpusDuo™ Er:YAG laser system for contact bone removal during oral surgical and periodontal procedures.

From Lumenis Inc. 3 Jan 2005

Chemotherapy lowers levels of antioxidants and micronutrients

Children undergoing chemotherapy for acute lymphoblastic leukemia (ALL) have significant changes in their antioxidant and micronutrient status which are related to their treatment outcomes, according to the results of a novel prospective study.

28 Dec 2004

Spinal cord injury and obesity

Researchers at the University of Michigan Health System are looking at how people with spinal cord injury burn calories and how that is affected by their muscle mass and body weight. The goal is to make better recommendations to people with spinal cord injury, but the research will also translate into greater understanding of obesity in the general population as well.

26 Dec 2004

New gel promotes healing by gluing bone pieces together

A new material that fuses biological and synthetic substances at the molecular level speeds bone and cartilage repair. Its creators at the Technion-Israel Institute of Technology say laboratory studies have shown the new gel promotes healing by gluing bone pieces together and stimulating tissue development.

26 Dec 2004

40-year tale of investigation and innovation into the challenge of hip implant failure

A remarkable story of how a new disease was inadvertently caused by successful medical treatment, ultimately understood, and eventually defeated by scientific innovation is being told a major player in the process.

22 Dec 2004

Stem cells transplanted to female foetus

A female foetus with multiple intrauterine fractures, diagnosed as severe osteogenesis imperfecta, was transplanted with HLA-mismatched mesenchymal stem cells (MSCs) in the 32nd week of gestation.

21 Dec 2004

Study finds new method can improve chemo survival

Seeking to find a way to lessen patients’ vulnerability to deadly infections following chemotherapy, researchers at the Stanford University School of Medicine have figured out a way to boost the immune function in animals following such treatments.

21 Dec 2004

European market for bone morphogenic proteins in spine fusion

High growth is forecast for novel technologies used either as adjuncts or as alternatives to current surgical procedures for the fusion of spinal vertebrae. Bone morphogenic proteins (BMP) - a new and innovative class of natural growth factors - represent amongst the most exciting of these niches.

20 Dec 2004

Gene therapy effective in helping children with severe combined immunodeficiency (SCID)

A UK study in this week’s issue of THE LANCET provides further evidence that gene therapy can be effective in creating a functional immune system for infants with severe combined immunodeficiency (SCID).

20 Dec 2004

10 to 20 million people in the United States have chronic kidney disease but most don’t know it

10 to 20 million people in the United States have chronic kidney disease but most don’t know it, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health, the National Institute of Diabetes and Digestive and Kidney Diseases and the National Center for Health Statistics.

19 Dec 2004

Link found between bisphosphonates and a serious bone disease called osteonecrosis of the jaw

Doctors at Long Island Jewish (LIJ) Medical Center recently discovered a link between a common chemotherapy drug and a serious bone disease called osteonecrosis of the jaw (ONJ).

13 Dec 2004

Diabetics who do not have good control over their blood sugar levels are more susceptible to oral health problems

Diabetes affects 18.2 million people in the United States and is expected to double by the year 2010. Additionally, diabetics who do not have good control over their blood sugar levels are more susceptible to oral health problems than non-diabetics

13 Dec 2004

Bone News and Research

Medical device innovations - fabricating the future

Promising new evidence for the optimal use of biologic therapies for rheumatoid arthritis

Strong association between high levels of hyaluronic acid and severe osteoarthritis

Potential cure for lymphoma in HIV patients

Stem cells from umbilical cord blood effectively treated heart attacks

Calcium intake contributing factor in formation of kidney stones

Signaling molecule involved in osteoarthritis identified

Least forceful way to deliver a baby whose shoulders are stuck in the birth canal

FDA clearance for laser contact bone removal

Chemotherapy lowers levels of antioxidants and micronutrients

Spinal cord injury and obesity

New gel promotes healing by gluing bone pieces together

40-year tale of investigation and innovation into the challenge of hip implant failure

Stem cells transplanted to female foetus

Study finds new method can improve chemo survival

European market for bone morphogenic proteins in spine fusion

Gene therapy effective in helping children with severe combined immunodeficiency (SCID)

10 to 20 million people in the United States have chronic kidney disease but most don’t know it

Link found between bisphosphonates and a serious bone disease called osteonecrosis of the jaw

Diabetics who do not have good control over their blood sugar levels are more susceptible to oral health problems

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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