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Single dose phase I data on CG53135 for the prevention of oral mucositis

CuraGen Corporation has announced results presented from a Phase I clinical trial with CG53135 for the prevention of oral mucositis (OM) in patients receiving high dose chemotherapy (HDCT) followed by autologous hematopoietic stem cell transplantation (AHSCT) at the ASH 46th Annual Meeting in San Diego, CA.

5 Dec 2004

Low level exposure to Benzene causes lower blood cell counts

A new study found that white blood cell counts were lowered in workers exposed to less than 1 ppm of the chemical benzene (part benzene per million parts air).

3 Dec 2004

Method for healing spinal injuries in dogs offers hope for preventing human paralysis

Lab tests have shown that an injection of a liquid polymer known as polyethylene glycol (PEG), if administered within 72 hours of serious spinal injury, can prevent most dogs from suffering permanent spinal damage.

3 Dec 2004

Guidelines needed for the use of androgens for women with sexual dysfunction

The Endocrine Society, which represents more than 12,000 endocrinologists who are specially trained to diagnose, treat and conduct basic and clinical research on complex hormonal disorders, has called for new clinical guidelines on the use of androgens in women/female sexual dysfunction.

3 Dec 2004

Tofu-based biomaterial that can help mend broken bones

A new Tofu-based biomaterial that can help mend broken bones and damaged tissues is being developed thanks to an investment of £149,000 from NESTA (the National Endowment for Science, Technology and the Arts), the organization that champions UK creativity and innovation.

2 Dec 2004

Thyroid treatments can set off radiation detectors

Medical procedures such as iodine therapy, a popular thyroid treatment, can result in patients triggering radiation detectors for up to three months after treatment, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

30 Nov 2004

Imatinib mesylate (Gleevec) inhibits important pathways that spur cancer growth

A new clinical study has shown that imatinib mesylate (Gleevec) has activity in AIDS-related Kaposi's sarcoma (KS). Imatinib inhibits important pathways that spur cancer growth, resulting in the regression of KS tumors within 4 weeks in some patients. The study will be published November 30 in the Journal of Clinical Oncology (JCO).

30 Nov 2004

Low testosterone production appears to be a common complication of type 2 diabetes in men

Moreover, results of the investigation show that this condition, known clinically as hypogonadism, is caused not by a defect in the testes, where testosterone is produced, but by improper functioning of the pituitary gland, which controls production of testosterone, or of the hypothalamus, the region of the brain that controls the pituitary.

29 Nov 2004

Study finds that stomach cancer originates from bone marrow derived stem cells, rather than from stomach stem cells

A common assumption among cancer specialists is that most cancers originate from tissue stem cells – for example, the gastric stem cells contained in the lining of the stomach.

29 Nov 2004

Stem cells derived from umbilical cords are a viable and effective transplant source for thousands of leukemia patients

A new study published in the New England Journal of Medicine confirms that stem cells derived from the umbilical cords of newborn babies are a viable and effective transplant source for thousands of leukemia patients who have no other treatment option.

24 Nov 2004

Scientists join forces to improve the effectiveness of a drug used to treat chronic myeloid leukaemia

Scientists from Glasgow and Liverpool are joining forces to improve the effectiveness of a drug used to treat a form of leukaemia, chronic myeloid leukaemia (CML), which affects 750 people in the UK each year.

24 Nov 2004

Testosterone has both a physiological and a psychological impact on women’s sexuality

A recently published dissertation from the Karolinska Institutet in Sweden shows that testosterone has both a physiological and a psychological impact on women’s sexuality.

23 Nov 2004

Stem cells' repair skills could be link to cancer

Johns Hopkins researchers say there is growing evidence that stem cells gone awry in their efforts to repair tissue damage could help explain why long-term irritation, such as from alcohol or heartburn, can create a breeding ground for certain cancers.

23 Nov 2004

Cells from skeletal muscle could be an important source of stem cells for repairing damaged muscle or nerve tissue

A group of cells called skeletal-muscle satellite cells are able to regenerate muscle fibres. Giulio Alessandri (Carlo Besta Neurological Institute, Milan, Italy) and colleagues investigated whether these cells can differentiate into different types of mesenchymal cell (the types of cell that eventually form connective tissue, bone, cartilage, and the circulatory and lymphatic systems).

18 Nov 2004

Hormone replacement therapy patches have considerable potential as prostate cancer therapy

Men using the female estrogen hormone replacement therapy (HRT) patches as treatment for advanced prostate cancer suffer fewer side effects than with other treatments, according to a new study reported in the latest issue of the Journal of Urology.

16 Nov 2004

Heart bypass gets new source for replacement blood vessels

The search for a stable, renewable source of blood vessels, especially for potential use in heart bypass surgery, has reached a milestone at the State University of New York at Buffalo.

11 Nov 2004

Abbott's investigational anti-interleukin-12 fully human monoclonal antibody in Crohn's disease study

Results of a Phase II study of Abbott's ABT-874, a fully human anti-interleukin-12 (IL-12) monoclonal antibody, will appear tomorrow in the New England Journal of Medicine citing treatment with ABT-874 shows differences in response and remission in patients with active Crohn's disease compared to placebo, in one arm of the study.

10 Nov 2004

Fresh insight into how teenage girls with anorexia nervosa really feel about themselves

A new University of Western Sydney study has given a fresh insight into how teenage girls with anorexia nervosa really feel about themselves, paving the way for more effective treatments for the potentially fatal eating disorder.

9 Nov 2004

First ever study of parental role in children's cancer treatment

A team of Detroit-based researchers, led by a behavioral scientist from the Barbara Ann Karmanos Cancer Institute, has launched a unique study to learn how parents can best help their children deal with painful procedures required for cancer treatment.

9 Nov 2004

Impaired cognitive and motor function following stem cell transplantation for severe blood disorders can improve

Patients who suffer a loss of cognitive and motor function as a result of stem cell transplantation for severe blood disorders are likely to see those functions return to previous levels after one year, according to a new study in the November 15, 2004, issue of Blood, the official journal of the American Society of Hematology.

8 Nov 2004

Bone News and Research

Single dose phase I data on CG53135 for the prevention of oral mucositis

Low level exposure to Benzene causes lower blood cell counts

Method for healing spinal injuries in dogs offers hope for preventing human paralysis

Guidelines needed for the use of androgens for women with sexual dysfunction

Tofu-based biomaterial that can help mend broken bones

Thyroid treatments can set off radiation detectors

Imatinib mesylate (Gleevec) inhibits important pathways that spur cancer growth

Low testosterone production appears to be a common complication of type 2 diabetes in men

Study finds that stomach cancer originates from bone marrow derived stem cells, rather than from stomach stem cells

Stem cells derived from umbilical cords are a viable and effective transplant source for thousands of leukemia patients

Scientists join forces to improve the effectiveness of a drug used to treat chronic myeloid leukaemia

Testosterone has both a physiological and a psychological impact on women’s sexuality

Stem cells' repair skills could be link to cancer

Cells from skeletal muscle could be an important source of stem cells for repairing damaged muscle or nerve tissue

Hormone replacement therapy patches have considerable potential as prostate cancer therapy

Heart bypass gets new source for replacement blood vessels

Abbott's investigational anti-interleukin-12 fully human monoclonal antibody in Crohn's disease study

Fresh insight into how teenage girls with anorexia nervosa really feel about themselves

First ever study of parental role in children's cancer treatment

Impaired cognitive and motor function following stem cell transplantation for severe blood disorders can improve

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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