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IU researchers identify potential target to improve functional recovery after spinal cord injury

Researchers at Indiana University School of Medicine have made several novel discoveries in the field of spinal cord injuries. Most recently, the team led by Xiao-Ming Xu, PhD, has been working to determine how to activate movement after a spinal cord injury at the ninth thoracic level, where nerve fibers from the brain down to the spinal cord are interrupted.

22 Dec 2019

Sphingotec's penKid is a reliable marker for detection and monitoring of acute kidney injury

Diagnostics company SphingoTec GmbH today reported on the publication of novel study results of its proprietary kidney function biomarker penKid® in BMC Emergency Medicine.

21 Dec 2019

Study uncovers a previously unknown subtype of muscle stem cells

Scientists have discovered a new subtype of muscle stem cells. These cells have the ability to build and regenerate new muscles, making them interesting targets for the development of gene therapies.

21 Dec 2019

Inhibition of a single enzyme may reduce heparin-induced thrombocytopenia

Heparin is widely used as an anticoagulant, but evokes in some patients a potentially life-threatening condition called HIT. Clinical scientists at Ludwig-Maximilians-Universitaet in Munich have now shown that inhibition of a single enzyme may markedly reduce this risk.

21 Dec 2019

Artificial intelligence can detect AML with high reliability

Artificial intelligence can detect one of the most common forms of blood cancer - acute myeloid leukemia (AML) - with high reliability.

20 Dec 2019

Data results of NCI-MATCH trial in tumors with DNA mismatch repair deficiencies

Final results are published from an evaluation of 42 patients treated with the immune checkpoint inhibitor nivolumab in the large multi-arm precision medicine trial, NCI-Molecular Analysis for Therapy Choice (NCI-MATCH or EAY131).

20 Dec 2019

Scientists explain how a common virus causes havoc on bone marrow, organ transplant patients

For the first time, scientists have discovered the molecular mechanism behind how a common virus can wreak havoc on bone marrow and organ transplant patients, according to a paper published in the journal Cell & Host Microbe.

19 Dec 2019

Penn researchers use MRI scans to predict 10-year breast cancer recurrence

Diverse diseases like breast cancer can present challenges for clinicians, specifically on a cellular level. While one patient's tumor may differ from another's, the cells within the tumor of a single patient can also vary greatly.

19 Dec 2019

New antibody shows promise in active lupus

A new trial involving the use of an antibody called anifrolumab reports improvement in patients with systemic lupus erythematosus (SLE) after 52 weeks of treatment. The research, titled 'Trial of Anifrolumab in Active Systemic Lupus Erythematosus', is published in the New England Journal of Medicine.

19 Dec 2019

Maintenance chemotherapy after initial treatment more beneficial for metastatic colorectal cancer patients

A Mayo Clinic study involving 5,540 patients with metastatic colorectal cancer finds that maintenance chemotherapy after initial treatment is more beneficial for patients whose disease is under control, compared with more aggressive treatment.

19 Dec 2019

New set of recommendations for clinicians to address youth vaping

In response to the pressing public health issue of vaping, clinicians of all disciplines are being asked to address this issue with youth, families and community members, despite minimal youth-focused screening or treatment guidelines.

19 Dec 2019

The number of people who need renal replacement therapy is increasing

The ERA-EDTA Registry collects data on renal replacement therapy from the national and regional renal registries in Europe and from countries bordering the Mediterranean. For the 2017 Annual Report, data sets from 53 national or regional renal registries in 37 countries were compiled. A total population of 694,024,000 people was analyzed.

19 Dec 2019

FDA approves new drug to treat adults with advanced urothelial or bladder cancer

The U.S. Food & Drug Administration granted accelerated approval to the drug enfortumab vedotin (EV) to treat adult patients with advanced urothelial or bladder cancer.

19 Dec 2019

Gastroesophageal reflux disease may affect nearly a third of U.S. adults every week

Gastroesophageal reflux disease (GERD), a digestive disorder that causes hearburn and other uncomfortable symptoms, may affect nearly a third of U.S. adults each week, and most of those who take certain popular medications for it still have symptoms, according to a new Cedars-Sinai study.

19 Dec 2019

Attention training is a promising augment for anxiety in children who do not respond to CBT

Between 30 to 50 percent of youth in the United States diagnosed with an anxiety disorder fail to respond to cognitive-behavior therapy (CBT).

19 Dec 2019

New review provides guidance to address gaps in transgender health care

One of the biggest barriers to care for transgender individuals is a lack of knowledgeable providers.

19 Dec 2019

A new book on ovarian cancer

An opening discussion of contemporary management of this disease presents commentary on surgery and clinical trials: neoadjuvant, dose-dense, and heated intraperitoneal chemotherapy (HIPEC}, as well as immunotherapy, vaccine therapy, emerging therapies.

18 Dec 2019

IncludeHealth and Cincinnati Children's join hands to commercialize movement correction technology

IncludeHealth, an internationally recognized provider of inclusive digital health and performance technologies, and Cincinnati Children's Hospital Medical Center, a top-ranked pediatric medical center and research institution, announced today an exclusive licensing agreement to allow IncludeHealth to commercialize a research based digital health technology originally developed at Cincinnati Children's.

18 Dec 2019

Developing brain vulnerable to HIV despite early treatment

A new study on how the HIV infection affects the development of intellect and other areas of brain development in children shows that early treatment doesn’t completely avert these negative outcomes. The paper, published in the journal Clinical Infectious Diseases shows that HIV in children can lead to impaired learning, reasoning and brain functioning.

18 Dec 2019

Clinical study demonstrates effective alternative to mastectomy for recurrent breast cancer

Mastectomy has historically been the standard treatment for breast cancer patients experiencing recurrence after an initial lumpectomy and whole-breast radiation. Now, a phase 2 clinical trial led by Douglas W. Arthur, M.D., chair and professor in the Department of Radiation Oncology at VCU Massey Cancer Center and VCU School of Medicine, has demonstrated an effective alternative.

18 Dec 2019

Therapy News and Research

IU researchers identify potential target to improve functional recovery after spinal cord injury

Sphingotec's penKid is a reliable marker for detection and monitoring of acute kidney injury

Study uncovers a previously unknown subtype of muscle stem cells

Inhibition of a single enzyme may reduce heparin-induced thrombocytopenia

Artificial intelligence can detect AML with high reliability

Data results of NCI-MATCH trial in tumors with DNA mismatch repair deficiencies

Scientists explain how a common virus causes havoc on bone marrow, organ transplant patients

Penn researchers use MRI scans to predict 10-year breast cancer recurrence

New antibody shows promise in active lupus

Maintenance chemotherapy after initial treatment more beneficial for metastatic colorectal cancer patients

New set of recommendations for clinicians to address youth vaping

The number of people who need renal replacement therapy is increasing

FDA approves new drug to treat adults with advanced urothelial or bladder cancer

Gastroesophageal reflux disease may affect nearly a third of U.S. adults every week

Attention training is a promising augment for anxiety in children who do not respond to CBT

New review provides guidance to address gaps in transgender health care

A new book on ovarian cancer

IncludeHealth and Cincinnati Children's join hands to commercialize movement correction technology

Developing brain vulnerable to HIV despite early treatment

Clinical study demonstrates effective alternative to mastectomy for recurrent breast cancer

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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