Immune System News and Research

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ImaginAb announces completion of $21M Series B financing

ImaginAb, Inc., a clinical stage biotechnology company that engineers antibodies into smaller protein formats optimized for in vivo molecular imaging, announced today the completion of a $21M Series B financing of the company, led by Mérieux Développement and syndicated with Novartis Venture Funds, Cycad Group and Nextech Invest.

9 May 2014

New technique expands number of functional cord blood stem cells for transplantation

Adults suffering from diseases such as leukemia, lymphoma, and other blood-related disorders may benefit from life-saving treatment commonly used in pediatric patients. Researchers at the Icahn School of Medicine at Mount Sinai have identified a new technique that causes cord blood (CB) stems cells to generate in greater numbers making them more useful in adult transplantation.

8 May 2014

Mouse mothers can protect pups from developing type 1 diabetes by eating gluten-free diet

New experiments on mice show, that mouse mothers can protect their pups from developing type 1 diabetes by eating a gluten-free diet. According to preliminary studies by reseachers at the University of Copenhagen, the findings may apply to humans.

8 May 2014

Rigel Pharmaceuticals reports net loss of $22.3 million for first quarter 2014

Rigel Pharmaceuticals, Inc. today reported financial results for the first quarter ended March 31, 2014.

7 May 2014

Breastfeeding promotes growth of beneficial lactic acid bacteria in baby's gut flora

The nutritional factor that has the greatest impact on the development of a child's gut flora is whether the child is breastfed, according to a new study by the National Food Institute, Technical University of Denmark, and the University of Copenhagen.

7 May 2014

TGen/George Mason create strategic research alliance to benefit patients with cancer, life-threatening illnesses

The Translational Genomics Research Institute (TGen) and George Mason University today announced the creation of a strategic research alliance to benefit patients with cancer and other life-threatening illnesses.

7 May 2014

RPCI research finds patients with metastatic kidney cancer benefit from HDIL-2 immunotherapy

A retrospective study published online ahead of print in the medical journal Urology by a physician team from Roswell Park Cancer Institute (RPCI) found that patients with metastatic kidney cancer — even those with chronic renal insufficiency — can tolerate and benefit from a treatment called high-dose interleukin-2 (HDIL-2) immunotherapy.

7 May 2014

Rice University researchers find new possibilities for benign, 'tunable' virus

Rice University scientists have designed a tunable virus that works like a safe deposit box. It takes two keys to open it and release its therapeutic cargo.

7 May 2014

Researchers discover genetic risk factor for premature birth

Researchers at the University of California, San Diego School of Medicine have discovered a genetic risk factor for premature birth.

7 May 2014

Inflammatory pneumococcal response differs by age

The composition of inflammatory lung infiltrate in people with pneumonia caused by Streptococcus pneumoniae differs by age, an in-situ study reveals.

6 May 2014

FDA accepts Merck's MK-3475 BLA for review

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for review the Biologics License Application (BLA) for MK-3475, Merck's investigational anti-PD-1 antibody, for the treatment of unresectable or metastatic melanoma in patients who have been previously treated with ipilimumab.

6 May 2014

Medela signs agreement to acquire enteral feeding assets of Acacia

Medela today announced the signing of an agreement to acquire the enteral feeding assets of Acacia, Inc., a Brea, Calif.-based company that designs and produces a line of high-quality neonatal feeding devices.

6 May 2014

New study explores how bacterial pathogen Yersinia tries to outsmart immune cell responses

A new study led by scientists at the University of Pennsylvania School of Veterinary Medicine has painted a clearer picture of the delicate arms race between the human immune system and a pathogen that seeks to infect and kill human cells.

6 May 2014

Bristol-Myers Squibb to present new immunotherapy study data at ASCO Annual Meeting

Bristol-Myers Squibb Company today announced that new data from studies investigating its immunotherapies in adjuvant and advanced melanoma, non-small cell lung cancer (NSCLC) and metastatic renal cell carcinoma (mRCC) will be presented at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago from May 30-June 3.

6 May 2014

BeiGene receives $5M from Merck to develop BGB-283 BRAF inhibitor

BeiGene (Beijing), Co., Ltd., an innovative oncology company focused on developing targeted and immune-oncology therapeutics, today announced the achievement of a clinical milestone in the company's collaboration with Merck Serono, the biopharmaceutical division of Merck, Darmstadt, Germany, for BGB-283, a second-generation BRAF inhibitor candidate currently in Phase 1 development.

6 May 2014

Study links nerve damage after hip surgery to inflammatory neuropathy

A recent Mayo Clinic Proceedings article links some nerve damage after hip surgery to inflammatory neuropathy. Historically, nerve damage from hip surgery has been attributed to mechanical factors caused by anesthesiologists or surgeons, such as positioning of the patient during surgery or direct surgical injury of the nerves.

6 May 2014

UH biomedical engineer receives ALR grant to study cause of lupus nephritis

In the U.S. alone, more than 1.5 million people have lupus, a chronic autoimmune disease in which the immune system turns against itself, attacking a person's healthy tissue, cells and organs. The symptoms can range from debilitating pain and fatigue to organ failure.

6 May 2014

BrightFocus Foundation honors 5 outstanding scientists in fields of macular degeneration, glaucoma

The BrightFocus Foundation today honored five outstanding scientists in the fields of macular degeneration and glaucoma, presenting them with named research awards at an event during the annual meeting of the Association for Research in Vision and Ophthalmology.

6 May 2014

New research reveals that eczema may lower skin cancer risk

Eczema caused by defects in the skin could reduce the risk of developing skin cancer, according to new research by King's College London. The immune response triggered by eczema could help prevent tumour formation by shedding potentially cancerous cells from the skin.

6 May 2014

Scientists develop bone marrow-on-a-chip to test effects of new drugs, toxic agents on bone marrow

The latest organ-on-a-chip from Harvard's Wyss Institute for Biologically Inspired Engineering reproduces the structure, functions and cellular make-up of bone marrow, a complex tissue that until now could only be studied intact in living animals, Institute researchers report in the May 4, 2014, online issue of Nature Methods.

6 May 2014

Immune System News and Research

ImaginAb announces completion of $21M Series B financing

New technique expands number of functional cord blood stem cells for transplantation

Mouse mothers can protect pups from developing type 1 diabetes by eating gluten-free diet

Rigel Pharmaceuticals reports net loss of $22.3 million for first quarter 2014

Breastfeeding promotes growth of beneficial lactic acid bacteria in baby's gut flora

TGen/George Mason create strategic research alliance to benefit patients with cancer, life-threatening illnesses

RPCI research finds patients with metastatic kidney cancer benefit from HDIL-2 immunotherapy

Rice University researchers find new possibilities for benign, 'tunable' virus

Researchers discover genetic risk factor for premature birth

Inflammatory pneumococcal response differs by age

FDA accepts Merck's MK-3475 BLA for review

Medela signs agreement to acquire enteral feeding assets of Acacia

New study explores how bacterial pathogen Yersinia tries to outsmart immune cell responses

Bristol-Myers Squibb to present new immunotherapy study data at ASCO Annual Meeting

BeiGene receives $5M from Merck to develop BGB-283 BRAF inhibitor

Study links nerve damage after hip surgery to inflammatory neuropathy

UH biomedical engineer receives ALR grant to study cause of lupus nephritis

BrightFocus Foundation honors 5 outstanding scientists in fields of macular degeneration, glaucoma

New research reveals that eczema may lower skin cancer risk

Scientists develop bone marrow-on-a-chip to test effects of new drugs, toxic agents on bone marrow

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