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Researchers analyse hydrogen bonds in tiny fibrils of amyloid-beta peptide

Using solid-state nuclear magnetic resonance (NMR) spectroscopy, researchers at Luleå University of Technology in collaboration with Warwick University in the UK for the first time in the world managed to analyse hydrogen bonds in tiny fibrils of Amyloid-beta peptide , which probably causes Alzheimer's disease.

5 Nov 2012

Depomed third quarter 2012 revenue increases to $33.3 million

Depomed, Inc. today reported financial results for the quarter and nine months ended September 30, 2012.

5 Nov 2012

Inhibition of NOX4 enzyme plays an important role in liver fibrosis

Researchers at the Bellvitge Biomedical Research Institute (IDIBELL) have led a study published in PLoS One showing that the inhibition of a family member of NADPH oxidase enzyme, NOX4, plays an important role in liver fibrosis.

5 Nov 2012

Endo, Bioniche decide to end second Urocidin Phase III trial on non-muscle-invasive bladder cancer

Bioniche Life Sciences Inc., a research-based, technology-driven Canadian biopharmaceutical company, today announced that a second Phase III clinical trial with Urocidin in non-muscle-invasive bladder cancer is being discontinued.

5 Nov 2012

Affymetrix reports net loss of $17.9 million for third quarter 2012

Affymetrix, Inc., today reported its operating results for the third quarter of 2012. Total revenue for the quarter was $79.6 million, including approximately $17.6 million in revenue from eBioscience during the third quarter of 2012. This compares to total revenue of $64.0 million for the same period of 2011.

5 Nov 2012

Viewpoints: Romney, Obama offer details of their plans; The 'passionate supply-sider' who taught Paul Ryan; Medicare plan has not 'doomed GOP'

All presidential elections matter. This one matters a great deal. It matters to the senior who needs medical care but, thanks to ObamaCare, can't find a doctor who is taking new Medicare patients. ... This election is about them. It is about all of us. ... It is about the education of our children, the value of our homes, the take-home pay from our jobs, the price of the gasoline we buy, the choices we have in our health care.

5 Nov 2012

Urban outdoor aerobic training may have negative health effects

Training outside in an urban environment may not be as beneficial for a person’s health as they might hope, suggests research.

5 Nov 2012

Overweight, smoking add to rheumatoid arthritis risk

Lifestyle changes could reduce the risk for rheumatoid arthritis in patients predisposed to the condition, Dutch researchers suggest.

5 Nov 2012

Anti-TNF-α therapy reduces CVD risk in patients with rheumatoid arthritis

Patients with rheumatoid arthritis exhibit a sub-clinical vasculitis that may underlie their increased risk for cardiovascular disease, shows research.

5 Nov 2012

Cervical cancer risk remains high after CIN treatment

Women who undergo treatment for screening-detected cervical intraepithelial neoplasia are more than four times more likely to develop cervical cancer than women with normal smear tests, research suggests.

5 Nov 2012

Round-the-clock ICU intensivists could reduce mortality rates, length of stay

Implementing 24-hour intensivists at medical intensive care units could reduce patient mortality rates, and significantly reduce patients' length of stay, indicate study results.

5 Nov 2012

Genetic polymorphisms linked with community-acquired pneumonia

Seven genetic polymorphisms have been shown to be associated with community-acquired pneumonia, research shows.

5 Nov 2012

Suicide rates in the US have increased sharply since the economic crisis began

Suicide rates in the US have risen sharply since the economic crisis took hold in 2007, warn the authors of Correspondence published Online First in The Lancet.

5 Nov 2012

AcelRx commences dosing in ARX-04 sufentanil NanoTab Phase 2 study for acute and breakthrough pain

AcelRx Pharmaceuticals, Inc., a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for the treatment of acute and breakthrough pain, today announced that it has dosed the first subjects in a Phase 2, placebo-controlled, dose-finding study of its ARX-04 sufentanil NanoTab product candidate.

5 Nov 2012

Self-harm among young people should not be over-interpreted

Self-harm is common among young people. Many have at one time scratched, punctured or cut themselves or hit their head forcefully against a wall, and the behaviour is almost as common among boys as girls. However, it may not be appropriate to compare young people who self-harm and adult psychiatric patients who self-harm. Knowledge is needed in order not to over-interpret the behaviour of the young people, according to psychologist Jonas Bjärehed, who has recently presented his thesis at Lund University in Sweden.

5 Nov 2012

Larger aneurysms linked to greater fluctuations in flow behaviour

Brain aneurysms occur in about six percent of the population. They are dilated sections of blood vessels, which can deteriorate over time until the blood vessel wall ruptures, resulting in a haemorrhage. This causes a loss of mental functions and severe headaches. Haemorrhages of this kind can even be life threatening. The treatment of such patients involves complex medical decision-making. The models developed by Julia Mikhal can be of great use in this regard.

5 Nov 2012

First Edition: November 5, 2012

Today's headlines include reports about the final round of polls, forecasts regarding which party will control the House and Senate and analysis of how campaign-trail messages have been playing during the election season's final hours.

5 Nov 2012

PsiOxus receives UK government grant to initiate ColoAd1 Phase I/II trial for ovarian cancer

PsiOxus Therapeutics, Ltd., a development stage biotechnology company, today announced the award of a £1.7 million ($2.7 million) grant from the UK government-backed Biomedical Catalyst to initiate a Phase I/II clinical trial to assess the use of ColoAd1 in the treatment of platinum-resistant, recurrent ovarian cancer.

5 Nov 2012

Study compares effectiveness of CABG surgery with PCI for adults with diabetes and heart disease

Adults with diabetes and multi-vessel coronary heart disease who underwent cardiac bypass surgery had better overall heart-related outcomes than those who underwent an artery-opening procedure to improve blood flow to the heart muscle, according to the results from an international study. The research was supported by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health.

5 Nov 2012

SpinChip aims to help doctors analyse patients' blood samples on the spot

The Norwegian company SpinChip aims to help doctors analyse patients' blood samples on the spot and provide immediate results.

5 Nov 2012

Research News and Research

Researchers analyse hydrogen bonds in tiny fibrils of amyloid-beta peptide

Depomed third quarter 2012 revenue increases to $33.3 million

Inhibition of NOX4 enzyme plays an important role in liver fibrosis

Endo, Bioniche decide to end second Urocidin Phase III trial on non-muscle-invasive bladder cancer

Affymetrix reports net loss of $17.9 million for third quarter 2012

Viewpoints: Romney, Obama offer details of their plans; The 'passionate supply-sider' who taught Paul Ryan; Medicare plan has not 'doomed GOP'

Urban outdoor aerobic training may have negative health effects

Overweight, smoking add to rheumatoid arthritis risk

Anti-TNF-α therapy reduces CVD risk in patients with rheumatoid arthritis

Cervical cancer risk remains high after CIN treatment

Round-the-clock ICU intensivists could reduce mortality rates, length of stay

Genetic polymorphisms linked with community-acquired pneumonia

Suicide rates in the US have increased sharply since the economic crisis began

AcelRx commences dosing in ARX-04 sufentanil NanoTab Phase 2 study for acute and breakthrough pain

Self-harm among young people should not be over-interpreted

Larger aneurysms linked to greater fluctuations in flow behaviour

First Edition: November 5, 2012

PsiOxus receives UK government grant to initiate ColoAd1 Phase I/II trial for ovarian cancer

Study compares effectiveness of CABG surgery with PCI for adults with diabetes and heart disease

SpinChip aims to help doctors analyse patients' blood samples on the spot

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