Mutation News and Research

RSS

Troponin genes offer new insights to familial heart failure

Mutations in the troponin protein complex may be useful for predicting the course of heart failure due to dilated cardiomyopathy and also for guiding treatment and research, according to a new study in the Nov. 16, 2004 issue of the Journal of the American College of Cardiology.

16 Nov 2004

Study clarifies BRCA1 and BRCA2 links with other cancers

The largest population study ever done into the risk of cancer in families that fulfil the criteria for BRCA1 and BRCA2 mutation testing has confirmed that breast and ovarian cancers are the major concerns for geneticists and doctors counselling families.

14 Nov 2004

Stem cell gene linked to a portion of one of the most common childhood brain cancers

Scientists at Johns Hopkins have linked a stem-cell gene to a portion of one of the most common childhood brain cancers, opening the door to tailored therapies that block the gene's tumor-promoting ability.

10 Nov 2004

Discovery of new gene that protects against lung cancer

Cancer Research UK scientists have discovered a new gene that protects against lung cancer, according to a study published in the journal PNAS.

9 Nov 2004

Researchers have documented a novel form of resistance in leukemia cells to an anti-cancer drug

Researchers at Virginia Commonwealth University’s Massey Cancer Center have documented a novel form of resistance in leukemia cells to an anti-cancer drug, which could help scientists develop new strategies for treating the disease.

8 Nov 2004

Researchers attempt to quantify processes underlying cell heterogeneity

Combining the latest methods in gene splicing and computer modeling, Rice University researchers are trying to develop a predictive framework for one of the most basic and complex biological phenomena — cellular heterogeneity, or the ability of genetic clones to act and behave differently when exposed to the same set of environmental stimuli.

8 Nov 2004

Search for genetic key to corneal disease

A new federal grant focusing on painful inherited visual disorders that scar the cornea will allow researchers to narrow the genetic cause of one type of corneal dystrophy and to offer improved diagnosis of this family of diseases.

8 Nov 2004

Autophagy may even provide a clue to the mythical fountain of youth

The cells of higher organisms have an internal mechanism for chewing up and recycling parts of themselves, particularly in times of stress, like starvation and disease. But nobody is quite sure yet whether this recently discovered process protects cells, or causes damage.

5 Nov 2004

alpha4 may prove to be useful target for smoking addiction therapies

Nicotine is responsible for more than four million smoking-related deaths each year. Yet people still smoke. Why? One reason is the stranglehold of addiction, started when nicotine enhances the release of a neurotransmitter called dopamine

4 Nov 2004

Sensor protein that identifies DNA breaks and activates the p53 cell-death program has been identified

DNA breaks from radiation, toxic chemicals, or other environmental causes occur routinely in cells and, unless promptly and properly repaired, can lead to cancer-causing mutations.

4 Nov 2004

Gene mutations responsible for causing cataracts in children, identified

Gene mutations responsible for causing cataracts in children have been identified by a team of University of Utah vision researchers. The discovery was reported in a recent issue of The Journal of Medical Genetics.

4 Nov 2004

Genetic mutations could collectively raise bowel cancer risk

Cancer Research UK scientists at the University of Oxford have found that a number of genetic mutations could collectively raise bowel cancer risk, reporting their findings in the journal PNAS.

4 Nov 2004

Some allergic conditions could increase your risk of suffering from blood cancer

Some allergic conditions could increase your risk of suffering from blood cancer as an adult, according to a new study published in the November 2004 issue of BMC Public Health. This is important news for the increasingly large numbers of allergy sufferers worldwide.

4 Nov 2004

Scientists have identified the gene which produces the hereditary Park8 variant of Parkinson’s

Research began when doctors discovered that various members of the same family had Parkinson’s. There are many kinds of Parkinson’s and some are hereditary.

4 Nov 2004

Improved risk classification for patients with acute lymphoblastic leukemia offers hope for eliminating irradiation

Improved risk classification for patients with acute lymphoblastic leukemia (ALL), coupled with more intensive intrathecal chemotherapy for high risk patients and the use of a drug called dexamethasone, could one day permit physicians to omit irradiation as a part of routine treatment.

1 Nov 2004

New rapid gonorrhea test that does not require collection

Potential antimicrobial resistance in the bacteria that cause gonorrhea can be detected without culturing the organism, thanks to a rapid test developed by researchers at Johns Hopkins.

1 Nov 2004

Researchers provide concrete evidence about how the human eye evolved

When Darwin's skeptics attack his theory of evolution, they often focus on the eye. Darwin himself confessed that it was "absurd" to propose that the human eye, an "organ of extreme perfection and complication" evolved through spontaneous mutation and natural selection.

1 Nov 2004

Gene silencing may provide hope for leukemia sufferers

Ever since the approval of Gleevec in 2001, a cancer-cell-specific drug used to treat chronic myelogenous leukemia (CML), the field of cancer therapeutics has been rushing full speed into the era of so-called "targeted" medicines.

1 Nov 2004

Cellular enzyme represents a potential new target for developing improved HIV drugs

Scientists have discovered that a cellular enzyme helps ferry HIV genetic instructions out of the cell nucleus where they can then be translated into proteins to begin their most destructive work.

1 Nov 2004

Interaction of nervous system proteins help researchers better understand age-related memory and hearing loss

In a finding that may one day help researchers better understand age-related memory and hearing loss, scientists have shown that two key nervous system proteins interact in a manner that helps regulate the transmission of signals in the nervous system.

29 Oct 2004

Mutation News and Research

Troponin genes offer new insights to familial heart failure

Study clarifies BRCA1 and BRCA2 links with other cancers

Stem cell gene linked to a portion of one of the most common childhood brain cancers

Discovery of new gene that protects against lung cancer

Researchers have documented a novel form of resistance in leukemia cells to an anti-cancer drug

Researchers attempt to quantify processes underlying cell heterogeneity

Search for genetic key to corneal disease

Autophagy may even provide a clue to the mythical fountain of youth

alpha4 may prove to be useful target for smoking addiction therapies

Sensor protein that identifies DNA breaks and activates the p53 cell-death program has been identified

Gene mutations responsible for causing cataracts in children, identified

Genetic mutations could collectively raise bowel cancer risk

Some allergic conditions could increase your risk of suffering from blood cancer

Scientists have identified the gene which produces the hereditary Park8 variant of Parkinson’s

Improved risk classification for patients with acute lymphoblastic leukemia offers hope for eliminating irradiation

New rapid gonorrhea test that does not require collection

Researchers provide concrete evidence about how the human eye evolved

Gene silencing may provide hope for leukemia sufferers

Cellular enzyme represents a potential new target for developing improved HIV drugs

Interaction of nervous system proteins help researchers better understand age-related memory and hearing loss

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Latest News