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Using saliva to predict COVID-19 severity in children

News-Medical speaks to Dr. Usha Sethuraman about her research into COVID-19 and how saliva could be used to help predict COVID-19 severity in children.

22 Oct 2021

Replication of SARS-CoV-2 variants in different cell and organ models

In this study, the replication of B.1.1.7 viruses was analyzed in different cell and organ models and dwarf hamsters.

22 Oct 2021

Development of a safe and effective COVID-19 nanoparticle vaccine

Researchers from ReVacc scientific have attempted to demonstrate the effectiveness of a new vaccine, REVC-128, two weeks post-administration.

22 Oct 2021

Hydrogel-based vaccine delivery system evokes antibody response against SARS-CoV-2

Researchers from Stanford University have been attempting to create a hydrogel-based vaccine delivery system that could improve the immune response's strength and duration.

22 Oct 2021

Boosting nonhuman primates with Moderna vaccine increases neutralizing antibody responses

Boosting nonhuman primates with the Moderna vaccine (mRNA-1273) six months after their primary vaccine series increased neutralizing activity against viral variants of concern, a new study shows.

22 Oct 2021

Bacteria defend themselves against viral predators with exchangeable genetic elements

Bacterial viruses, so-called phages, destroy bacteria. Bacteria are constantly exposed to viral attacks. A research team led by Martin Polz, a microbiologist at the University of Vienna, has now studied how bacteria defend themselves against viral predators.

22 Oct 2021

Researchers find a new way to analyze diseased and healthy cells from brain tumor patients

Scientists studying the most common and aggressive type of brain tumor in adults have discovered a new way of analyzing diseased and healthy cells from the same patient.

22 Oct 2021

New AI-based tool helps clinicians understand and better predict adverse effects of COVID-19

The symptoms and side effects of Covid-19 are scattered across a diagnostic spectrum. Some patients are asymptomatic or experience a mild immune response, while others report significant long-term illnesses, lasting complications, or suffer fatal outcomes.

22 Oct 2021

Targeted drug shows promising activity in kidney cancer patients with brain metastases

A targeted drug has shown promising activity against brain metastases resulting from kidney cancer, achieving a 50 percent response rate, and supporting further studies of the drug in this patient group whose poor prognosis has created a significant unmet need.

21 Oct 2021

Influence of age on innate and adaptive immunity in COVID-19 patients

A new study investigates how age influences SARS-CoV-2 replication, innate and adaptive immune responses.

21 Oct 2021

Researchers discover how Staphylococcus aureus protects itself against important antibiotic

The skin bacterium Staphylococcus aureus often develops antibiotic resistance. It can then cause infections that are difficult to treat.

21 Oct 2021

Cell-free DNA can help detect measurable residual disease in children with medulloblastoma

Scientists at St. Jude Children's Research Hospital have shown that cell-free DNA from cerebrospinal fluid (CSF) can be used to detect measurable residual disease (MRD) in children treated for the brain tumor medulloblastoma.

21 Oct 2021

Researchers identify a common gene variant that drives the efficiency and outcome of dialysis

Every day, the human kidneys clean about 1,500 liters of blood by producing approximately 1–2 liters of urine. Thereby, the body gets rid of excess water and toxic waste products of the metabolism or also drugs and maintains the balance of water and minerals in the tissues.

21 Oct 2021

Study reveals dual role of anti-cancer inhibitor

TG2, an enzyme known to help cancers spread more quickly, also plays a role in regulating T-cells, according to a Northwestern Medicine study published in the Journal for Immunotherapy of Cancer.

21 Oct 2021

Novel Einstein-developed strategy successfully suppresses HIV infections in mice

Armed with a novel strategy they developed for bolstering the body's immune response, scientists at Albert Einstein College of Medicine have successfully suppressed HIV infections in mice - offering a path to a functional cure for HIV and other chronic viral infections.

21 Oct 2021

CAR-T cell treatment's efficacy in hematological malignancies predicted by epigenetics

One in five cancers affects blood cells and lymph nodes, causing leukemias and lymphomas, respectively. Although their treatment with drugs has led to a great advance in their cure, there are cases where there is no clinical response or resistance to them is generated.

21 Oct 2021

Development of a plant-based platform for the production of SARS-CoV-2 antigen

Scientists have recently focused on the development of plant-based recombinant protein platforms.

21 Oct 2021

Immune responses to SARS-CoV-2 infection and vaccination in patients with multiple sclerosis

A new study has focused on the immune response in pwMS undergoing anti-CD20 treatment.

21 Oct 2021

Pitt researchers to contribute to building an atlas of cellular senescence

Most cells throughout the body can divide and multiply to replace old cells and repair damaged tissue, but in response to certain stresses, cells can lose their ability to proliferate. These so-called senescent cells accumulate with age and may contribute to cancer and age-related disorders, such as chronic lung disease, cardiovascular disease, frailty and dementia, by pumping out signals that damage neighboring tissues.

21 Oct 2021

Researchers employ novel algorithm to identify candidate cancer drugs for pulmonary hypertension

By combining computational and experimental approaches, University of Pittsburgh School of Medicine and Prairie View A&M University researchers identified cancer drugs that show promise for treating pulmonary hypertension, or PH, a rare and incurable lung disease.

21 Oct 2021

B Cell News and Research

Using saliva to predict COVID-19 severity in children

Replication of SARS-CoV-2 variants in different cell and organ models

Development of a safe and effective COVID-19 nanoparticle vaccine

Hydrogel-based vaccine delivery system evokes antibody response against SARS-CoV-2

Boosting nonhuman primates with Moderna vaccine increases neutralizing antibody responses

Bacteria defend themselves against viral predators with exchangeable genetic elements

Researchers find a new way to analyze diseased and healthy cells from brain tumor patients

New AI-based tool helps clinicians understand and better predict adverse effects of COVID-19

Targeted drug shows promising activity in kidney cancer patients with brain metastases

Influence of age on innate and adaptive immunity in COVID-19 patients

Researchers discover how Staphylococcus aureus protects itself against important antibiotic

Cell-free DNA can help detect measurable residual disease in children with medulloblastoma

Researchers identify a common gene variant that drives the efficiency and outcome of dialysis

Study reveals dual role of anti-cancer inhibitor

Novel Einstein-developed strategy successfully suppresses HIV infections in mice

CAR-T cell treatment's efficacy in hematological malignancies predicted by epigenetics

Development of a plant-based platform for the production of SARS-CoV-2 antigen

Immune responses to SARS-CoV-2 infection and vaccination in patients with multiple sclerosis

Pitt researchers to contribute to building an atlas of cellular senescence

Researchers employ novel algorithm to identify candidate cancer drugs for pulmonary hypertension

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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