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Researchers uncover potential new target to fight inflammatory diseases

An international team of researchers have uncovered a drug-like compound that blocks a crucial inflammatory pathway, potentially paving the way for a new treatment for a host of diseases - including COVID-19.

19 Nov 2020

Detectable SARS-CoV-2 antibodies 120 days post-infection in Chicago case study

In a recent study, a team of researchers at Northwestern University, USA, had found that nearly 20 percent seroprevalence in the United States metropolitan site, Chicago, over the summer, during a period when lockdown restrictions were eased. They found that three-quarters of seropositive individuals retained detectable antibodies for at least 120 days or four months.

19 Nov 2020

SARS-CoV-2 immunity can last over six months, study finds

US-based scientists have released a study on preprint server bioRxiv*, titled “Immunological memory to SARS-CoV-2 assessed for greater than six months after infection,” contributing to the enormous research effort currently underway in this area.

19 Nov 2020

New, non-invasive method for diagnosing and preventing colorectal cancer

Researchers from the University of Alicante(UA) and Alicante General University Hospital's Institute for Health and Biomedical Research (ISABIAL) have developed a new non-invasive method for diagnosing and preventing colorectal cancer (CRC) through the analysis of volatile organic compounds in stool samples.

19 Nov 2020

UK’s COVID-19 vaccine shows similar safety and immunogenicity results in healthy older adults

The UK's vaccine against SARS-CoV-2 shows similar safety and immunogenicity results in healthy older adults (aged 56 years and over) to those seen in adults aged 18-55 years.

19 Nov 2020

Researchers use bioinformatics methods to identify key genes in dilated cardiomyopathy

In a new publication from Cardiovascular Innovations and Applications, Yukuan Chen, Xiaohui Wu, Danchun Hu and Wei Wang, from the Shantou University Medical College, Shantou, China and Second Affiliated Hospital of Shantou University Medical College, Shantou, China consider the importance of mitochondrial-related genes in dilated cardiomyopathy.

19 Nov 2020

Genetic variations of SARS-CoV-2 transmission in cats

Using cats as an animal model to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission, researchers have determined the virus has a narrow transmission bottleneck.

19 Nov 2020

Researchers investigate challenges of treating acute myocardial infarction caused by variant angina

In a new publication from Cardiovascular Innovations and Applications, Wen-Yuan Ding, Jia-Min Li, Fei Zheng, Li-Li Wang, Xin-Yi Wei and Guo-Hua Li from Shandong Provincial Qianfoshan Hospital, Ji'nan, China, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Ji'nan, China and Shandong First Medical University, Tai'an, China consider the challenges of treating acute myocardial infarction due to variant angina.

19 Nov 2020

Research on genetic heart disease uncovers new mechanism for heart failure

Research on genetic heart disease has uncovered a new and unexpected mechanism for heart failure. This landmark discovery found a correlation between the clumping of RNA-binding proteins long linked to neurodegenerative disease and the aggregates of protein found in the heart tissue of patients with RBM20 dilated cardiomyopathy.

19 Nov 2020

Scientists identify previously unknown mechanism that drives tumor spread

Any given tumor is composed of a multitude of cell types that can each look or behave differently from its neighbors.

19 Nov 2020

Study identifies enzyme vital to the metastatic growth of prostate cancer cells

While prostate cancer originates within the prostate, metastasis, or the spread of a tumor from the site of origin to other organs, remains a leading cause of death among people with the disease.

19 Nov 2020

Alzheimer's study shows tau protein changes according to dementia stage

Research into Alzheimer's disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients' brain tissue, a pathological form of the tau protein contributes to propagating the disease in the brain.

19 Nov 2020

New technique gives a "street view" of vital lipid membranes surrounding organelles

The ability to "see" the inner workings of structures (organelles) within cells, in real time, offers the promise of advancements in disease diagnosis and treatment.

18 Nov 2020

Researchers assess consequences of decades of global nutrition transition

Just a handful of rice and beans - a part of our world is starved. Hawaiian Pizza and ice-cream - another part of our world is stuffed, throwing away food every day.

18 Nov 2020

New understanding of glycan signatures of the SARS-COV-2 S1 spike protein

A team of scientists from the University of Oxford, UK, has revealed that site-specific glycosylation differs between spike proteins derived from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and a viral vector-based vaccine candidate.

18 Nov 2020

Optimizing SARS-COV-2 inactivation for COVID-19 research at lower biosafety levels

Researchers at Montana State University have validated and compared two methods for inactivating the causative agent of coronavirus disease 2019 (COVID-19) that would enable the virus to be studied at a lower biosafety level (BSL) than the one currently required.

18 Nov 2020

"Escape mutations" could help SARS-CoV-2 evade immune attack

Researchers in the United States have identified mutations within severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – that can reduce antibody binding to the virus, potentially mediating its escape from immune attack.

18 Nov 2020

Brain protein plays a major role in the development and growth of pancreatic cancer

Researchers have discovered that a protein thought to only be involved in the development of neurons in the brain also plays a major role in the development and growth of pancreatic cancer.

18 Nov 2020

Researchers use proteogenomics to better understand the biological complexity of breast cancer

Researchers at Baylor College of Medicine, the Broad Institute of MIT and Harvard and other institutions have applied powerful proteogenomics approaches to better understand the biological complexity of breast cancer.

18 Nov 2020

Immunotherapies effective against lung cancer, melanoma may also work against rare skin tumor

Cutaneous angiosarcoma is a rare, highly aggressive skin tumor found primarily on the scalps of older White people, but based on new research from the University of North Carolina School of Medicine and the Lineberger Comprehensive Cancer Center, immunotherapies effective against lung cancer and melanoma may also work against this cancer.

18 Nov 2020

Protein C News and Research

Researchers uncover potential new target to fight inflammatory diseases

Detectable SARS-CoV-2 antibodies 120 days post-infection in Chicago case study

SARS-CoV-2 immunity can last over six months, study finds

New, non-invasive method for diagnosing and preventing colorectal cancer

UK’s COVID-19 vaccine shows similar safety and immunogenicity results in healthy older adults

Researchers use bioinformatics methods to identify key genes in dilated cardiomyopathy

Genetic variations of SARS-CoV-2 transmission in cats

Researchers investigate challenges of treating acute myocardial infarction caused by variant angina

Research on genetic heart disease uncovers new mechanism for heart failure

Scientists identify previously unknown mechanism that drives tumor spread

Study identifies enzyme vital to the metastatic growth of prostate cancer cells

Alzheimer's study shows tau protein changes according to dementia stage

New technique gives a "street view" of vital lipid membranes surrounding organelles

Researchers assess consequences of decades of global nutrition transition

New understanding of glycan signatures of the SARS-COV-2 S1 spike protein

Optimizing SARS-COV-2 inactivation for COVID-19 research at lower biosafety levels

"Escape mutations" could help SARS-CoV-2 evade immune attack

Brain protein plays a major role in the development and growth of pancreatic cancer

Researchers use proteogenomics to better understand the biological complexity of breast cancer

Immunotherapies effective against lung cancer, melanoma may also work against rare skin tumor

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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