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Study shows how Notch gene and PRC2 protein complex work together to cause T-ALL

A new study published in the journal Nature Medicine by NYU Cancer Institute researchers, shows how the cancer causing gene Notch, in combination with a mutated Polycomb Repressive Complex 2 (PRC2) protein complex, work together to cause T- cell acute lymphoblastic leukemia.

13 Jan 2012

Caltech researchers devise new method to make complex molecules

A team of researchers at the California Institute of Technology (Caltech) has devised a new method for making complex molecules. The reaction they have come up with should enable chemists to synthesize new varieties of a whole subclass of organic compounds called nitrogen-containing heterocycles, thus opening up new avenues for the development of novel pharmaceuticals and natural products ranging from chemotherapeutic compounds to bioactive plant materials such as morphine.

12 Jan 2012

St. Jude introduces 'Explore' website for pediatric genome project

St. Jude Children's Research Hospital has launched a freely available website for published research results from the St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project (PCGP). The PCGP is the largest effort to date aimed at sequencing the entire genomes of both normal and cancer cells from pediatric cancer patients, comparing differences in the DNA to identify genetic mistakes that lead to childhood cancers.

12 Jan 2012

Damon Runyon Cancer Research Foundation names 18 new Fellows

The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting innovative early career researchers, named 18 new Damon Runyon Fellows at its fall Fellowship Award Committee review.

11 Jan 2012

Foundation Medicine, Sanofi enter strategic collaboration for cancer genome analysis

Foundation Medicine, Inc., a molecular information company that brings comprehensive cancer genome analysis to routine clinical care, today announced the initiation of a strategic collaboration with Sanofi.

11 Jan 2012

END7 campaign aims to combat seven major NTDs by 2020

Launched today, the END7 campaign is dedicated to eliminating seven major neglected tropical diseases (NTDs) as a public health threat to poor communities by the end of 2020.

10 Jan 2012

Pfizer commences PF-05280602 Phase 1 trial in hemophilia A & B

Catalyst Biosciences, Inc., the leading company in the discovery and development of engineered proteases, today announced that Pfizer Inc. has initiated a Phase 1 clinical trial for PF-05280602, an investigational proprietary, engineered variant of recombinant human Factor VIIa developed by Catalyst Biosciences.

6 Jan 2012

LANL's top 10 science stories of 2011

Los Alamos National Laboratory's top 10 science stories of 2011 illustrate the broad variety of scientific excellence that's the hallmark of the Laboratory. This year's stories include alternative energy research, world record magnetic fields, disease tracking, the study of Mars, climate change, fuel cells, solar wind, and magnetic reconnection.

26 Dec 2011

Researchers develop CAD-type tools to engineer RNA control systems

The computer assisted design (CAD) tools that made it possible to fabricate integrated circuits with millions of transistors may soon be coming to the biological sciences. Researchers at the U.S. Department of Energy (DOE)'s Joint BioEnergy Institute (JBEI) have developed CAD-type models and simulations for RNA molecules that make it possible to engineer biological components or "RNA devices" for controlling genetic expression in microbes.

23 Dec 2011

Bacteria use host proteins to build camouflaged homes inside healthy cells

Bacteria are able to build camouflaged homes for themselves inside healthy cells - and cause disease - by manipulating a natural cellular process.

21 Dec 2011

Study on how Antarctic worms survive current levels of ocean warming

Researchers at the University of Delaware are examining tiny worms that inhabit the frigid sea off Antarctica to learn not only how these organisms adapt to the severe cold, but how they will survive as ocean temperatures increase.

21 Dec 2011

Cancer screening: Is it necessary in the elderly?

There is a long ongoing debate on whether the elderly need to be routinely screened for cancers. A new survey shows that the majority of nearly 19 million Americans over age 75 dutifully get screened for breast, prostate, and colon cancers each year.

14 Dec 2011

FDA approves Lannett's ANDA for Triamterene with Hydrochlorothiazide Capsules

Lannett Company, Inc. today announced it has received approval from the U.S. Food and Drug Administration (FDA) of its Abbreviated New Drug Application (ANDA) for Triamterene with Hydrochlorothiazide 37.5/25mg Capsules.

13 Dec 2011

Study highlights need for greater recognition of sexual and reproductive healthcare needs of teen boys

Two newly published reports by investigators at the Johns Hopkins Children's Center highlight the need for greater recognition of the sexual and reproductive healthcare needs of teen boys and enumerate the essential services this traditionally overlooked group should receive at least once a year.

9 Dec 2011

Breakthrough advance in tackling dangerous 'bad' cholesterol in the body

Scientists from the University of Leicester and University of California Los Angeles (UCLA) have announced a breakthrough advance in tackling dangerous 'bad' cholesterol in the body.

9 Dec 2011

Collaboration of public and private health partners is essential for health improvement

Improving health is too multifaceted to be left solely in the hands of those working in the health sector alone, according to the latest Healthy People 2020 Objectives for the Nation. A recent shift in national health priorities has led Healthy People, a program that sets the national agenda for health promotion and disease prevention, to add 'social determinants' into its 2020 goals.

8 Dec 2011

Bold move by Astra Zeneca to share 22 early stage potential drugs with MRC

Drug maker AstraZeneca will be sharing 22 of its early-stage research compounds with the Medical Research Council as part of a make over of life sciences research. This would speed up patients’ access to breakthrough drugs and arrest the decline of research and development in the UK.

6 Dec 2011

Nations at Busan Forum sign non-binding declaration to form worldwide aid partnership

Representatives of organizations and governments from 160 countries "agreed on Thursday to form a worldwide partnership to ensure tens of billions of dollars in foreign aid goes to help the neediest," Agence France-Presse reports.

3 Dec 2011

ASH recognizes abstract presenters at 53rd annual meeting in San Diego

The American Society of Hematology (ASH) recognizes the following abstract presenters at the 53rd ASH annual meeting in San Diego, CA, with the highest scoring abstracts in the categories of undergraduate student, medical student, graduate student, resident physician, and postdoctoral fellow.

2 Dec 2011

New technique to accomplish 'accelerated serendipity' using robotics

Scientists can now take that "a-ha" moment to go with a method Princeton University researchers developed - and successfully tested - to speed up the chances of an unexpected yet groundbreaking chemical discovery.

29 Nov 2011