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Scientists engineer tissue grafts for personalized joint replacement

The temporomandibular joint (TMJ), which forms the back portion of the lower jaw and connects your jaw to your skull, is an anatomically complex and highly loaded structure consisting of cartilage and bone.

14 Oct 2020

Combining genetic and experimental data can enable more accurate prediction of influenza virus

Combining genetic and experimental data into models about the influenza virus can help predict more accurately which strains will be most common during the next winter, says a study published recently in eLife.

14 Oct 2020

Statins may lower cancer risk through a pathway unrelated to cholesterol

Cholesterol-lowering drugs called statins may reduce cancer risk in humans through a pathway unrelated to cholesterol, says a study published today in eLife.

13 Oct 2020

Novel findings on mole growth could pave way for skin cancer treatments

Moles stop growing when they reach a certain size due to normal interactions between cells, despite having cancer-associated gene mutations, says a new study published today in eLife.

13 Oct 2020

Researchers identify a mechanism to prevent hair loss

An international research group headed by Associate Professor Sara Wickström at the University of Helsinki has identified a mechanism that is likely to prevent hair loss.

13 Oct 2020

Stem cells that repair broken bones can also generate arthritic bone spurs

The same stem cells that heal broken bones can also generate arthritic bone spurs called osteophytes, according to a new study in the Annals of the Rheumatic Diseases.

12 Oct 2020

Penn receives $4.5 million NIH grant to create a comprehensive resource for women’s health

Junhyong Kim, PhD, Chair and Patricia M. Williams Professor of Biology in the School of Arts and Sciences, and Kate O'Neill, MD MTR, Assistant Professor, Department of Obstetrics and Gynecology in the Perelman School of Medicine, have been awarded a Human BioMolecular Atlas Program (HuBMAP) grant supported by the Eunice Kennedy Shriver National Institute of Child Health & Human Development and the Common Fund of the National Institutes of Health.

9 Oct 2020

Scientists map genetic networks that control the biology of regulatory T cells

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed.

1 Oct 2020

Researchers identify the target structures for T-cell response against SARS-CoV-2

Our immune system can efficiently fend off viral diseases. Two types of immune cells play an important role in this process: The T-cells, which firstly can directly destroy virus-infected cells and secondly enable the formation of efficient, virus-neutralizing antibodies by B-cells.

30 Sep 2020

Blocking the self-destruction process of enzymes can mitigate age-related diseases

Stopping the cannibalistic behavior of a well-studied enzyme could be the key to new drugs to fight age-related diseases, according to a new study published online in Nature Cell Biology.

30 Sep 2020

Acid reflux drug could help newborns recover from hypoxic-ischemic encephalopathy

Researchers in China have discovered a potential way to prevent a lack of oxygen or blood flow from causing long-lasting brain damage in newborn children.

29 Sep 2020

Study unravels how lysosomal damage response pathways prevent kidney injury

Human cells need to work like well-oiled machines to keep our bodies running as they should. Waste products such as misfolded proteins, damaged cellular components, and carbohydrates get in the way and must be quickly disposed of.

28 Sep 2020

Researchers discover specific cellular pathway involved in lung tissue regeneration

Researchers at Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania have identified a cellular pathway that can be targeted with a naturally occurring drug to stimulate lung tissue regeneration, which is necessary for recovery from multiple lung injuries.

28 Sep 2020

New mechanism that prevents hair loss identified

A team of researchers from Cologne and Helsinki has discovered a mechanism that prevents hair loss: hair follicle stem cells, essential for hair to regrow, can prolong their life by switching their metabolic state in response to low oxygen concentration in the tissue.

28 Sep 2020

Study identifies hiding place where tumor cells shelter from chemotherapy in childhood leukemia

The stroma of the choroid plexus is one of the locations within the central nervous system (CNS) that serves as a shelter for tumor cells, allowing them to elude chemotherapy and potentially cause subsequent relapses in childhood acute lymphoblastic leukaemia, according to research led by the Complutense University of Madrid.

25 Sep 2020

Gruthan Bioscience to develop new class of cholesterol-lowering drugs

Gruthan Bioscience, LLC, a Medical University of South Carolina startup based in Charleston, South Carolina, received a Small Business technology Transfer (STTR) award from the National Heart, Blood and Lung Institute in August to take the next step in developing a novel class of cholesterol-lowering drugs to treat familial hypercholesterolemia.

24 Sep 2020

Intra-CREATE grants awarded to support research on personalized medicine and cell therapy

Researchers from Critical Analytics for Manufacturing Personalized-Medicine, an interdisciplinary research group at Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, have been awarded Intra-CREATE grants from the National Research Foundation Singapore to help support research on retinal biometrics for glaucoma progression and neural cell implantation therapy for spinal cord injuries.

22 Sep 2020

Researchers identify a compound that inhibits growth of schwannomas

Schwannomas are tumors of the peripheral nervous system, which often occur in the genetic disease neurofibromatosis type 2. The research group of Prof. Dr. Helen Morrison at the Leibniz Institute on Aging - Fritz Lipmann Institute in Jena, Germany, identified a compound that inhibits the growth of such tumors and improves nerve function.

21 Sep 2020

Scientists identify new drug to prevent SARS-CoV-2 infection consequences

Scientists from the Department of Cell Biology of the University of Malaga and the Andalusian Centre for Nanomedicine and Biotechnology have made progress in finding new rapid implementation therapies to combat the COVID-19 pandemic, identifying a new drug that could prevent or mitigate the consequences derived from SARS-CoV-2 infection.

19 Sep 2020

Enhancing the efficacy of anti-PD-L1 immunotherapy for cancer

For most people, there is no scarier diagnosis than that of cancer. While treatments including chemotherapy and radiotherapy have been used since the 1940s and late 1800s, respectively, immunotherapy has more recently emerged as a viable and successful approach to cancer treatment.

18 Sep 2020

Cell Biology News and Research

Scientists engineer tissue grafts for personalized joint replacement

Combining genetic and experimental data can enable more accurate prediction of influenza virus

Statins may lower cancer risk through a pathway unrelated to cholesterol

Novel findings on mole growth could pave way for skin cancer treatments

Researchers identify a mechanism to prevent hair loss

Stem cells that repair broken bones can also generate arthritic bone spurs

Penn receives $4.5 million NIH grant to create a comprehensive resource for women’s health

Scientists map genetic networks that control the biology of regulatory T cells

Researchers identify the target structures for T-cell response against SARS-CoV-2

Blocking the self-destruction process of enzymes can mitigate age-related diseases

Acid reflux drug could help newborns recover from hypoxic-ischemic encephalopathy

Study unravels how lysosomal damage response pathways prevent kidney injury

Researchers discover specific cellular pathway involved in lung tissue regeneration

New mechanism that prevents hair loss identified

Study identifies hiding place where tumor cells shelter from chemotherapy in childhood leukemia

Gruthan Bioscience to develop new class of cholesterol-lowering drugs

Intra-CREATE grants awarded to support research on personalized medicine and cell therapy

Researchers identify a compound that inhibits growth of schwannomas

Scientists identify new drug to prevent SARS-CoV-2 infection consequences

Enhancing the efficacy of anti-PD-L1 immunotherapy for cancer

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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