Central Nervous System News and Research

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Study: Exposure to air particulate matter impairs metabolism of olfactory mucosal cells

Exposure to air particulate matter impairs the metabolism of olfactory mucosal cells, according to a recent study from the University of Eastern Finland. The results can contribute to a better understanding of how air pollutants may harm brain health, as the olfactory mucosa can act as a key pathway to the brain.

15 Jun 2020

Creating the first 3D neural map of a heart

News-Medical spoke to Dr. Vadigepalli and Dr. Schwaber about their groundbreaking research in which they managed to map the neurons in the heart.

15 Jun 2020

Researchers question the mechanism of retinitis pigmentosa

Researchers who made a knock-in mouse-model of the genetic disorder retinitis pigmentosa 59, or RP59, expected to see retinal degeneration and retinal thinning. As reported in the journal Cells, they surprisingly found none, calling into question the commonly accepted -- though never proved -- mechanism for RP59.

12 Jun 2020

Experts clarify MS subtypes to improve care and access to treatments

An international committee of multiple sclerosis (MS) experts has clarified their previously published descriptors of the different courses of MS and disease activity.

11 Jun 2020

Research team provides new insights on the communication between liver and brain

A research team in Vienna is investigating how calorie intake, liver activity and fat storage interact and what role the central nervous system plays in this.

10 Jun 2020

Registered COVID-19 clinical trials lack key features to optimize their scientific value

Most of the registered clinical trials of potential treatments for COVID-19 underway as of late March were designed in ways that will greatly limit their value in understanding potential treatments, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

10 Jun 2020

Research shows potential new therapeutic strategy for slowing down Huntington's disease

Scientists have described a potential new therapeutic strategy for slowing down early-stage Huntington's disease in a new study published today in eLife.

9 Jun 2020

SARS-CoV-2 invasion of central nervous system through olfactory tract

As the COVID-19 pandemic continues to claim lives throughout the world, the evidence is mounting that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the respiratory tract as well as the central nervous system. Now, a new study by German researchers published on the preprint server bioRxiv in June 2020 describes various neurological manifestations of COVID-19, as well as the underlying pathophysiology.

7 Jun 2020

GMU researchers studying effect of cannabidiol on exosome release

Fatah Kashanchi, Professor, Laboratory of Molecular Virology, School of Systems Biology, and Lance Liotta, Co-Director, Applied Proteomics and Molecular Medicine, are working to mitigate virally driven HIV pathenogenesis in the central nervous system.

5 Jun 2020

Study highlights increased consumption of opioids in patients with osteoarthritis

Fentanyl, tramadol or tilidine: New European figures show that even in Europe increasingly more people are taking opioids for pain connected with rheumatic and musculoskeletal diseases.

5 Jun 2020

Intranasal delivery of MSC-EVs shows promise for treating Alzheimer's disease

In the search for a cure for Alzheimer's disease, mesenchymal stem cells and their derived extracellular vesicles (MSC-EVs) offer much promise, thanks to their protective and anti-inflammatory properties.

4 Jun 2020

DFG to establish ten new Collaborative Research Centers

The Deutsche Forschungsgemeinschaft is establishing ten new Collaborative Research Centres to further support top-level research in German universities.

4 Jun 2020

AFFiRiS announces preclinical results of monoclonal antibody mAB C6-17 in Huntington's

AFFiRiS, a clinical-stage biotechnology company developing novel disease-modifying specific active immunotherapies, today announced that detailed preclinical results with its monoclonal antibody mAB C6-17 to treat Huntington's Disease were published in the peer-reviewed journal Neurobiology of Disease.

3 Jun 2020

Does smoking increase COVID-19 risk?

The COVID-19 pandemic continues to smolder and smoke in many parts of the world, with over 100,000 cases, and more than 3,000 deaths reported every day. Many factors are responsible for the higher risk of infection in certain specific population subgroups are known.

2 Jun 2020

Study looks at delirium in critically ill COVID-19 patients

A new study published on the online preprint server medRxiv in May 2020 reports on the high incidence of delirium in COVID-19 patients in intensive care. This highlights the urgent need to predict, prevent, and manage delirium and to cut it short in patients with COVID-19.

2 Jun 2020

Stem cell model sheds new light on the devastating process of neurodegeneration

A new study published today in Neuron led by The New York Stem Cell Foundation Research Institute's Valentina Fossati, Ph.D., creates astrocytes - an integral support cell in the brain - from stem cells and shows that in disease-like environments, these normally helpful cells can turn into neuron-killers.

1 Jun 2020