DNA Sequencing News and Research

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DNA modification can define early onset glioblastoma

A class of brain tumor that tends to emerge in younger patients but is less aggressive than others can be identified by examining DNA methylation of a specific set of genes, scientists at The University of Texas M. D. Anderson Cancer Center and colleagues with The Cancer Genome Atlas report today online at Cancer Cell.

16 Apr 2010

Ancient hunter-gatherers were lactose intolerant, says study

The hunter-gatherers who inhabited the southern coast of Scandinavia 4,000 years ago were lactose intolerant. This has been shown by a new study carried out by researchers at Uppsala University and Stockholm University.

2 Apr 2010

CLC bio signs partnership agreement with Ion Torrent

CLC bio, the world's leading bioinformatics solution provider, today announced a partnership with Ion Torrent, a new sequencing company started by Dr. Jonathan Rothberg, the founder of 454 Life Sciences. The partnership will ensure that data can directly flow off of the Ion Personal Genome Machine sequencer and into CLC bio's solutions, like CLC Genomics Workbench or CLC Genomics Server.

30 Mar 2010

Appeals court ruling clears way for Enzo Biochem to pursue claim for substantial damages against Applera

Enzo Biochem Inc. said today that a decision released Friday by the Court of Appeals for the Federal Circuit reversing a district court's summary judgment will enable the Company to pursue a claim for substantial damages against Applera Corporation, now Life Technologies Corporation. The Court of Appeals vacated the lower court's judgments of invalidity on United States Patent Nos. 5,328,824 and 5,449,767.

30 Mar 2010

New DNA test to detect Lyme disease spirochete infection

Many of the more than 30,000 people a year in the United States with suspected cases of Lyme disease spirochete (bacterial) infection can now take a DNA test developed by a Connecticut scientist/physician and his team that can quickly determine if they test positive for Lyme spirochetes in their blood.

30 Mar 2010

NIH grant for study on impact of gastric bypass surgery on Type II diabetes patients

Gastric bypass surgery, thought of by many as the last hope of morbidly obese people for losing weight, has many other benefits researchers are only beginning to understand.

25 Mar 2010

Survey unveils impact of gene regulation on human health

Researchers are only beginning to understand how individual variation in gene regulation can have a lasting impact on one's health and susceptibility to certain diseases. Now, an ambitious survey of the human genome has identified differences in the binding of master regulators called transcription factors to DNA that affect how genes are expressed in different people.

19 Mar 2010

International symposium to feature latest findings on vector-borne diseases in humans and plants

Leading insect vector biologists from around the world will gather at the University of California, Riverside for two days this month to discuss their latest research on vector-borne diseases in humans and plants.

16 Mar 2010

Enzo Biochem to market MultiGEN’s multiplex DNA sequencing based diagnostic tests in state of New York

Enzo Biochem, Inc. today announced that it has entered into an agreement with MultiGEN Diagnostics Inc., of San Diego, California, for exclusive rights to market MultiGEN’s unique diagnostic tests based on multiplex DNA sequencing, in the state of New York. In addition, Enzo has been granted marketing rights for other non-exclusive territories in United States.

15 Mar 2010

Microchip Biotechnologies renamed as IntegenX

Microchip Biotechnologies, a maker of automated microscale biotech laboratory systems, today announced that it has changed its business name to IntegenX. The new name articulates the company's focus on integrating sample preparation and analysis technologies into complete products that address generic problems shared by life science and biotechnology research laboratories worldwide.

12 Mar 2010

Whole genome sequencing of entire family beneficial

The Institute for Systems Biology (ISB) has analyzed the first whole genome sequences of a human family of four. The findings of a project funded through a partnership between ISB and the University of Luxembourg was published online today by Science on its Science Express website. It demonstrates the benefit of sequencing entire families, including lowering error rates, identifying rare genetic variants and identifying disease-linked genes.

11 Mar 2010

Scientists identify specific causative genetic mutation associated with CMT

Scientists using advanced genomic analysis technologies from Life Technologies Corporation have sequenced an individual’s genome and identified the specific causative mutation associated with Charcot-Marie-Tooth Disease (CMT), one of the most common inherited neurological disorders currently affecting 1 in 2,500 individuals in the United States.

11 Mar 2010

USF study: HHV-6 causes permanent infection by inserting its DNA into human chromosomes

Human herpesvirus 6 (HHV-6) infects nearly 100 percent of humans in early childhood, and the infection then lasts for the rest of a person's life. Now, a team led by Peter Medveczky, MD, a professor in the Department of Molecular Medicine at the University of South Florida, has discovered that in some individuals, HHV-6 causes such a permanent infection by inserting or "integrating" its DNA into human chromosomes.

9 Mar 2010

Researchers discuss possibility of using food to prevent individual's genes from expressing disease

Personal health recommendations and diets tailored to better prevent diseases may be in our future, just by focusing on genetics.

6 Mar 2010

Life Technologies announces early stage results from SMS technology

Life Technologies Corporation today announced early stage results from its single molecule sequencing (SMS) technology. The technology promises to combine virtually unlimited continuous long read lengths with unmatched accuracy to deliver targeted genomic sequence data in a matter of hours, paving the way for sequencing to become a commonplace tool in research laboratories and clinical settings worldwide.

2 Mar 2010

Agilent Technologies announces new multiplexing capability in SureSelect Target Enrichment System

Agilent Technologies Inc. today announced that its Agilent SureSelect Target Enrichment System supports multiplexed DNA sequencing of 12 to 16 samples per lane depending on the next-generation sequencing platform, reducing costs and increasing throughput up to 16-fold.

25 Feb 2010

SeqWright deploys Isilon scale-out NAS storage solution for next-generation genomic sequencing services

Isilon® Systems today announced that SeqWright has deployed Isilon scale-out NAS as an end-to-end storage solution for its full range of next-generation genomic sequencing services. By combining Isilon's X-Series, NL-Series and Backup Accelerator, SeqWright has created a comprehensive solution for every stage of its DNA sequencing workflow – from primary storage, to nearline archival, to tape backup – accelerating time-to-results without requiring full-time storage administration.

25 Feb 2010

Ion Torrent to award two Ion Personal Genome Machine sequencers through grant program

Ion Torrent™ today announced that it will award two Ion Personal Genome Machine (PGM™) sequencers in April 2010 through a grant program designed to help make DNA sequencing accessible to all scientists.

24 Feb 2010

CLC bio, Isilon Systems collaborate to eliminate analysis, storage bottlenecks in high-throughput sequencing workflows

Today, CLC bio, the world's leading bioinformatics solution provider, announced a partnership with Isilon® Systems, Inc. which will help the life science community eliminate some of the toughest workflow bottlenecks when working with high-throughput sequencing data: Analysis and storage.

24 Feb 2010

New genetic analysis system for forensic DNA testing laboratories launched

Life Technologies Corporation today announced the launch of a new genetic analysis system designed to optimize data quality and deliver increased reliability, performance, quality assurance and ease-of-use specifically for forensic DNA testing laboratories.

24 Feb 2010

DNA Sequencing News and Research

DNA modification can define early onset glioblastoma

Ancient hunter-gatherers were lactose intolerant, says study

CLC bio signs partnership agreement with Ion Torrent

Appeals court ruling clears way for Enzo Biochem to pursue claim for substantial damages against Applera

New DNA test to detect Lyme disease spirochete infection

NIH grant for study on impact of gastric bypass surgery on Type II diabetes patients

Survey unveils impact of gene regulation on human health

International symposium to feature latest findings on vector-borne diseases in humans and plants

Enzo Biochem to market MultiGEN’s multiplex DNA sequencing based diagnostic tests in state of New York

Microchip Biotechnologies renamed as IntegenX

Whole genome sequencing of entire family beneficial

Scientists identify specific causative genetic mutation associated with CMT

USF study: HHV-6 causes permanent infection by inserting its DNA into human chromosomes

Researchers discuss possibility of using food to prevent individual's genes from expressing disease

Life Technologies announces early stage results from SMS technology

Agilent Technologies announces new multiplexing capability in SureSelect Target Enrichment System

SeqWright deploys Isilon scale-out NAS storage solution for next-generation genomic sequencing services

Ion Torrent to award two Ion Personal Genome Machine sequencers through grant program

CLC bio, Isilon Systems collaborate to eliminate analysis, storage bottlenecks in high-throughput sequencing workflows

New genetic analysis system for forensic DNA testing laboratories launched

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