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Why some people can’t lose weight even when they follow the rules

New research reveals biological factors, not just effort, influence weight loss success, highlighting the need for personalized diet and exercise interventions.

13 Jan 2026

Dietary protein reshapes how cholera bacteria colonize the gut

Researchers investigate the role of dietary components and the gut microbiota in cholera.

13 Jan 2026

Discovery lays foundation for understanding how the cell senses membrane injuries

When the cell's recycling stations, the lysosomes, start leaking, it can become dangerous. Toxic waste risks spreading and damaging the cell.

12 Jan 2026

Brain immune cells drive persistent negative emotions after repeated binge drinking

New research has identified that neuroinflammation driven by microglia (immune cells in the brain) is a primary underlying driver of prolonged negative feelings caused by repeated, sustained binge drinking (binge exposure).

12 Jan 2026

Two harmful gene variants can combine to restore normal protein function

In a groundbreaking study published in the in Proceedings of the National Academy of Sciences (PNAS), scientists at Pacific Northwest Research Institute (PNRI) have overturned a long-held belief in genetics: that inheriting two harmful variants in the same gene always worsens disease.

12 Jan 2026

Digital twin technology guides personalized treatment for brain cancer patients

A new machine-learning-based approach to mapping real-time tumor metabolism in brain cancer patients, developed at the University of Michigan, could help doctors discover which treatment strategies are most likely to be effective against individual cases of glioma.

12 Jan 2026

Resistance to rezatapopt: New TP53 mutations identified in cancer patients

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for therapeutics.

12 Jan 2026

Blood test opens the doors to early diagnosis and prevention of Crohn's disease

Sinai Health researchers have shown a blood test that can predict Crohn's disease years before symptoms appear, opening the doors to early diagnosis and potentially prevention.

12 Jan 2026

Researchers discover how aggressive breast cancer controls protein production

A previously unknown mechanism that makes it possible for aggressive so-called triple-negative breast cancer to fine-tune its production of proteins has been discovered by researchers at Umeå University, Sweden.

12 Jan 2026

Multiple myeloma rates increasing twice as high in men than in women

Rates of multiple myeloma (MM), the second most common blood cancer in the United States, are increasing and are twice as high in men than in women

12 Jan 2026

DNA analysis of colorectal polyps improves diagnosis and treatment

In about 5–10% of colorectal cancer patients, hereditary factors play a role, with higher percentages among younger patients.

12 Jan 2026

Whole-genome sequencing improves PARP inhibitor treatment prediction

A whole-genome sequencing approach shows early promise over current commercial methods for identifying more patients likely to benefit from PARP inhibitor cancer treatments, according to a study led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

12 Jan 2026

Metabolic BMI reveals hidden health risks in normal weight individuals

People of normal weight may also be at risk of diabetes and similar diseases. A study from the University of Gothenburg reveals that those with an unexpectedly high so-called metabolic BMI have up to a five times higher risk level.

12 Jan 2026

AI automates sister chromatid exchange counting, improving diagnosis of Bloom syndrome

Researchers from Tokyo Metropolitan University have developed a suite of algorithms to automate the counting of sister chromatid exchanges (SCE) in chromosomes under the microscope.

10 Jan 2026

Study uncovers a neural brake that limits motivation during unpleasant situations

Most of us know the feeling: maybe it is making a difficult phone call, starting a report you fear will be criticized, or preparing a presentation that's stressful just to think about.

9 Jan 2026

One Health action needed as environmental reservoirs fuel drug-resistant infections

Environmental antimicrobial resistance is turning rivers, soils, and even the air into hidden highways for "superbugs," according to a new review that calls for urgent, coordinated action across human, animal, and environmental health.

9 Jan 2026

Earthworm-based composting offers a low-energy solution to antibiotic resistance

Earthworms could become unexpected allies in the global fight against antibiotic resistance, by helping farmers turn manure into safer, high-value organic fertilizer through a process called vermicomposting.

9 Jan 2026

George Mason trial: New pill aims to sustain weight loss after GLP-1s

GLP-1 medications like Ozempic and Wegovy have transformed obesity treatment, but maintaining weight loss after the medications stop remains a challenge.

9 Jan 2026

Key protein in the tuberculosis bacterium helps protect itself from foreign DNA

Researchers at the Indian Institute of Science (IISc), with collaborators from the Institute of Mathematical Sciences (IMSc), have discovered how a key protein in the tuberculosis bacterium helps protect it from the influence of foreign DNA inserted into its genome.

9 Jan 2026