Hyperactivity News and Research

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Teachers' perceptions of poor behavior leads to potential misdiagnosis of ADHD

Nearly 1 million children in the United States are potentially misdiagnosed with attention deficit hyperactivity disorder simply because they are the youngest - and most immature - in their kindergarten class, according to new research by a Michigan State University economist.

18 Aug 2010

Study links child’s date of birth with ADHD diagnosis rate

Rising rates of attention deficit hyperactivity disorder (ADHD) and large differences in diagnosis rates have led to fears that the condition is often being misdiagnosed. A new study from North Carolina State University demonstrates that these concerns are justified. The researchers found large discrepancies in diagnosis and treatment rates based on small differences in children's dates of birth.

18 Aug 2010

BioMarin commences Phase 3b study of Kuvan's neuropsychiatric effects in phenylketonuria patients

BioMarin Pharmaceutical Inc. announced today that the first subject has initiated treatment in a Phase 3b study (PKU-016) to evaluate the effects of Kuvan (sapropterin dihydrochloride) on neuropsychiatric symptoms in subjects with phenylketonuria (PKU). BioMarin expects to report results in the first half of 2012.

18 Aug 2010

KemPharm receives patent for LAT prodrug technology for Attention Deficit – Hyperactivity Disorder treatment

KemPharm, Inc. announced today that it has received a Notice of Issuance from the United States Patent and Trademark Office (USPTO) for its patent application entitled "Polar Hydrophilic Prodrugs of Amphetamine and Other Stimulants and Processes for Making and Using the Same", U.S. Patent No. 7,772,222. This patent protects broad aspects of the Company's core Ligand Activated Therapy (LAT) prodrug technology platform and its application to the treatment of Attention Deficit – Hyperactivity Disorder.

16 Aug 2010

Shire announces divestiture of Daytrana to Noven Pharmaceuticals

Shire plc, the global specialty biopharmaceutical company, announced the divestiture of Daytrana (methylphenidate transdermal system) to Noven Pharmaceuticals, Inc. Daytrana, which is approved and marketed in the US for the treatment of Attention Deficit Hyperactivity Disorder in children and adolescents, will continue to be available for patients through Noven.

11 Aug 2010

FDA clears Curemark's CM – 4612 IND for Phase III clinical trial in ADHD

Curemark, LLC, a drug research and development company focused on the treatment of neurological diseases, announced that the U.S. Food and Drug Administration has given clearance to Curemark's Investigational New Drug application for a Phase III clinical trial for the use of CM – 4612 in the treatment of attention deficit hyperactivity disorder.

11 Aug 2010

Noven enters agreement to acquire global rights to ADHD drug Daytrana from Shire

Noven Pharmaceuticals, Inc. today announced that it has entered into a Product and Trademark Acquisition Agreement with affiliates of Shire plc pursuant to which Noven will acquire global rights to Daytrana® (methylphenidate transdermal system) from Shire.

11 Aug 2010

Vyvanse Capsules CII demonstrates significant improvement in adults with ADHD: Phase 3b study

Shire plc, the global specialty biopharmaceutical company, today announced that a Phase 3b study published in Behavioral and Brain Functions found adults with Attention Deficit Hyperactivity Disorder who took once-daily Vyvanse (lisdexamfetamine dimesylate) Capsules CII demonstrated significant improvement in attention.

6 Aug 2010

Parents of kids with autism spectrum disorders more likely to split: Study

A new study has found that couples who have a child with an autism spectrum disorder (ASD) have an 80% risk of getting divorce. The Adolescents and Adults With Autism study involved 391 families with autistic children and compared them with other families whose children were developing normally. The families were matched based on the age, sex and birth order of the child with an ASD, as well as the age, ethnicity and education of the mother.

4 Aug 2010

Research examines effects of orthostatic hypotension in adults, children

A simple variation to the tried and true method of checking blood pressure can reveal startling information about both older and younger persons, new research suggests.

4 Aug 2010

Group skill building intervention programs for foster care children may help improve mental health

Incorporating mentoring and group skill-building intervention programs for children in foster care may help improve mental health outcomes in this population, according to a report in the August issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

3 Aug 2010

ADHD linked to poorer eating habits: Study

A new study by researchers in Perth has linked attention-deficit hyperactivity disorder with “western-style” diets in teenage sufferers. For the study the Telethon Institute for Child Health and Research examined the diets of 1,800 adolescents, categorizing them as either eating a healthy mix of fruit, vegetables, whole grains and fish or the “western-style” highly-processed, fried and take-away foods. The latter contained more food additives, flavors or colors, which could lead to hyperactivity or changes to chemicals that control parts of the brain dealing with attention and concentration say researchers.

29 Jul 2010

Aphios awarded US patent for compositions, methods for treating diseases involving 5-α reductase enzyme

Aphios® Corporation today announced that it was awarded United States Patent No. 7,744,935 B2 for "Compositions and Methods for Inhibiting 5-α Reductase," granted June 29, 2010. This invention is related to compositions and methods for treating diseases involving the 5-alpha (α) reductase enzyme.

28 Jul 2010

Students with ADHD less likely to finish high school graduation: Study

Teens with attention-deficit/hyperactivity disorder - the most common childhood psychiatric condition in the United States - are less likely to finish high school on time than students with other mental-health disorders that often are considered more serious, a large national study by researchers at the UC Davis School of Medicine has found. The study found that nearly one third of students with ADHD, twice the proportion as students with no psychiatric disorder, either drop out or delay high school graduation.

28 Jul 2010

Journal of Mental Health features special issue on diagnosing mental illness

This month Journal of Mental Health features a special issue on diagnosing mental illness. The issue - which comes out just weeks after the eagerly-awaited new draft of the Diagnostic and Statistical Manual of Mental Disorders, the global diagnostic 'bible' for the field of mental health medicine - includes a series of articles written by high profile mainstream personalities on what a diagnosis of mental illness has meant to them.

27 Jul 2010

Need for better understanding of appropriate treatment choices for children with insomnia: Study

A new survey of child psychiatrists indicates that insomnia is a major problem among children in mental health treatment and at least a quarter of these patients are given sleep medication. The results of the survey, conducted by Judith Owens, MD, a sleep expert with Hasbro Children's Hospital, and colleagues, suggests that management of insomnia in this population is a common practice, although the clinical approach varies widely. The study is published in the August 2010 edition of Sleep Medicine.

27 Jul 2010

NIH awards BU $1.6M grant to target protein-protein interactions with synthetic organic drugs

An interdisciplinary team of Boston University professors is launching a project to develop new ways to target protein-protein interactions with synthetic organic drugs. Financed by a four-year $1.6 million grant from the National Institutes of Health, the goal is to develop new approaches for discovering "drug-like" small molecule inhibitors against challenging protein-protein interaction (PPI) interfaces.

27 Jul 2010

Polyfluoroalkyl chemicals linked to ADHD in children

A new study led by a team of Boston University School of Public Health researchers suggests a link between polyfluoroalkyl chemicals (PFCs), industrial compounds which are widely used in many consumer products, and attention deficit hyperactivity disorder (ADHD) in children.

21 Jul 2010

Artificial colours in food linked to cancer and behavioral disorders in children: Study

Artificial colours in foods, scientists have found may increase the risk of getting cancer, allergies and may trigger hyperactivity in susceptible children. This new report entitled, “Food Dyes: A Rainbow of Risks”, has come from the research conducted by the Centre for Science in the Public Interest (CSPI).

18 Jul 2010

Shire receives FDA approval of Daytrana for ADHD in adolescents

Shire plc, the global specialty biopharmaceutical company, announced the US Food and Drug Administration (FDA) approval of Daytrana® (methylphenidate transdermal system) for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in adolescents aged 13 to 17 years. Daytrana, the first and only transdermal ADHD patch, is already an FDA-approved ADHD treatment for children 6 to 12 years. Daytrana is indicated as an integral part of a total treatment program for ADHD that may include other measures (psychological, educational, and social).

7 Jul 2010

Hyperactivity News and Research

Teachers' perceptions of poor behavior leads to potential misdiagnosis of ADHD

Study links child’s date of birth with ADHD diagnosis rate

BioMarin commences Phase 3b study of Kuvan's neuropsychiatric effects in phenylketonuria patients

KemPharm receives patent for LAT prodrug technology for Attention Deficit – Hyperactivity Disorder treatment

Shire announces divestiture of Daytrana to Noven Pharmaceuticals

FDA clears Curemark's CM – 4612 IND for Phase III clinical trial in ADHD

Noven enters agreement to acquire global rights to ADHD drug Daytrana from Shire

Vyvanse Capsules CII demonstrates significant improvement in adults with ADHD: Phase 3b study

Parents of kids with autism spectrum disorders more likely to split: Study

Research examines effects of orthostatic hypotension in adults, children

Group skill building intervention programs for foster care children may help improve mental health

ADHD linked to poorer eating habits: Study

Aphios awarded US patent for compositions, methods for treating diseases involving 5-α reductase enzyme

Students with ADHD less likely to finish high school graduation: Study

Journal of Mental Health features special issue on diagnosing mental illness

Need for better understanding of appropriate treatment choices for children with insomnia: Study

NIH awards BU $1.6M grant to target protein-protein interactions with synthetic organic drugs

Polyfluoroalkyl chemicals linked to ADHD in children

Artificial colours in food linked to cancer and behavioral disorders in children: Study

Shire receives FDA approval of Daytrana for ADHD in adolescents

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