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UCLA researchers discover new way to eliminate leukemia stem cells

The introduction of the drug imatinib in 2001 revolutionized the treatment of a type of cancer called chronic myelogenous leukemia. In more than 80% of people with CML who received the drug, the disease went into complete remission.

15 Oct 2019

Repurposed quinacrine can reduce tumor burden in mice bearing HNSCC xenograft tumors

The authors have developed the Accelera TED platform to repurpose drugs for HNSCC treatment; using in vitro assays and in vivo models.

11 Oct 2019

RTKI drugs may not significantly improve survival rates of patients during radiotherapy

Taking certain cancer-fighting drugs while undergoing radiation therapy may not increase survival for patients, but may, instead, increase side effects, according to a team of researchers. The drugs, however, may be beneficial for patients who are not undergoing radiation therapy.

10 Oct 2019

Researchers identify genetic mutation that causes idiopathic pulmonary fibrosis

Researchers in Japan have identified a genetic mutation that causes a severe lung disease called idiopathic pulmonary fibrosis by killing the cells lining the lung's airways.

10 Oct 2019

GUMC now offers three clinical trials to study treatments for LBD

Georgetown University Medical Center, a Lewy Body Dementia (LBD) Association Research Center of Excellence, is now offering three clinical trials to study new treatments for LBD, a disease often confused with Parkinson's and Alzheimer's disease.

8 Oct 2019

New way to prevent malaria bugs from breeding

A new international collaboration reports that the compound called TCMDC-135051 is capable of preventing the synthesis of a protein that is required for growth in Plasmodium falciparum, one of the species of the Plasmodium parasite that causes malaria. The study, reported in the journal Science, could lead to the development of a new antimalarial drug.

8 Oct 2019

Study may help in personalizing treatment for lung cancer, develop new drugs

Researchers at the University of Copenhagen have used highly sophisticated molecular analyses to identify key proteins in the signaling pathways that cancers use to spread in the body.

4 Oct 2019

Newly discovered molecular process could speed up recovery from nerve injuries

Twenty million Americans suffer from peripheral nerve injuries, which can be caused by traumas such as combat wounds and motorcycle crashes as well as medical disorders including diabetes.

3 Oct 2019

Cannabis: CBD vs THC causes lower psychiatric side-effects

A study has revealed how cannabidiol works against tetrahydrocannabinol to prevent psychiatric side effects.

1 Oct 2019

Study shows how cannabidiol blocks the psychiatric side-effects of THC

Researchers at Western University have shown for the first time the molecular mechanisms at work that cause cannabidiol, or CBD, to block the psychiatric side-effects caused by tetrahydrocannabinol, the main psychoactive chemical in cannabis.

30 Sep 2019

New trial shows improved survival for patients with advanced colorectal BRAF-mutant cancer

A clinical trial has shown that using a combination of three drugs that target a BRAF gene mutation in patients with mCRC effectively boosts overall survival.

30 Sep 2019

Study reveals molecular mechanism of cancer malignancy and development of leukemia

A Waseda University-led research uncovered the molecular mechanism of how a particular cancer-causing oncogene could trigger an onset of acute myeloid leukemia (AML).

30 Sep 2019

Adding targeted therapy drug to standard treatment benefits aggressive breast cancer patients

A study led by UCLA researchers found that adding ribociclib, a targeted therapy drug, to standard hormone therapy has been shown to significantly improve overall survival in postmenopausal women with advanced hormone-receptor positive/HER2- breast cancer, one of the most common forms of the disease.

29 Sep 2019