Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Aggressive breast cancer hijacks normal protective physiological process to survive

A member of a protein family known for protecting our cells also protects cancer cells in aggressive, metastatic breast cancer, scientists report.

3 Oct 2018

Aspirin shown to prevent the spread of cancer

New research by Cardiff University has demonstrated a role for Aspirin in the treatment of bowel, prostate and breast cancer.

1 Oct 2018

Researchers decipher antitumor mechanism of Amazonian plant in human cancer cells

A piece of research conducted by the Free Radicals and Oxidative Stress Group at the UPV/EHU's Faculty of Medicine and Nursing has deciphered the antitumor mechanism exerted by the plant Vismia baccifera, originally from the Amazonian region of Colombia, in human liver cancer cells.

28 Sep 2018

New findings show importance of physical forces in tumor metastasis

A malignant tumor is characterized by its ability to spread around its surroundings. To do so, tumor cells stick to the surrounding tissue (mainly collagen) and use forces to propel.

26 Sep 2018

Cancer Research UK, Keystone Symposia collaborate for cancer-related research

Keystone Symposia and Cancer Research UK are pleased to announce their new collaboration consisting of a series of annual cancer-related scientific research conferences organized by Keystone Symposia in collaboration with Cancer Research UK.

26 Sep 2018

Researchers discover novel targeting agents to prevent cancer metastasis

Recently, a research team led by Maurizio Pellecchia at the University of California, Riverside, discovered a way for chemotherapy drug paclitaxel to target migrating, or circulating, cancer cells, which are responsible for the development of tumor metastases.

26 Sep 2018

Study: Second opinion can potentially change the diagnosis of breast cancer patients

It's early morning and a team of more than 20 professionals cram around a long table in a dark room, peering at slide after slide of black-and-white mammogram images crossing the screen.

26 Sep 2018

VRK1 protein may enable cancer cells to colonize new areas of the body during metastasis

Sometimes negative results can point researchers in the right direction. In results published in PLOS ONE on September 4, 2018, scientists at the Medical University of South Carolina examined a protein called vaccinia-related kinase 1 that they hypothesized was important for metastasis. They found that, rather than causing cancer cells to migrate and invade, VRK1 over-expression had the opposite effect.

26 Sep 2018

Phase 1 and 2 clinical trials of entrectinib drug in ROS1-positive NSCLC show promising results

Results of phase 1 and phase 2 clinical trials of the drug entrectinib in ROS1-positive non-small cell lung cancer presented on the press program of the International Association for the Study of Lung Cancer 19th World Conference on Lung Cancer show a response rate of 77.4 percent for 53 patients evaluable for response, with median duration of response of 24.6 months.

25 Sep 2018

CHMP provides positive opinion to Cabometyx for previously-treated patients with hepatocellular carcinoma

Ipsen announced today that the Committee for Medicinal Products for Human Use, the scientific committee of the European Medicines Agency, provided a positive opinion for Cabometyx (cabozantinib) as a monotherapy for the treatment of hepatocellular carcinoma in adults who have been previously treated with sorafenib.

21 Sep 2018

Ipsen receives approval from Health Canada for CABOMETYX tablets for treating renal cell carcinoma

Exelixis, Inc. today announced that its partner Ipsen Biopharmaceuticals Canada Inc. received approval from Health Canada of CABOMETYX® tablets for the treatment of adults with advanced renal cell carcinoma who have received prior vascular endothelial growth factor targeted therapy.

19 Sep 2018

Highly personalized approach may help immune cells to eliminate melanoma

With new immunotherapy treatments for melanoma, recovery rates have risen dramatically, in some cases to around 50%.

12 Sep 2018

Researchers design new medicine to treat highly aggressive pancreatic cancer

A treatment for highly aggressive and commonly fatal pancreatic cancer is being developed, reports a University of Houston researcher who has designed a new medicine that can inhibit two of the major pathways of the deadly disease.

12 Sep 2018

Researchers untangle mysteries of 'evil' protein in ER-positive breast cancer

Breast cancer is one of the most common cancers in the United States, striking 1 out of 8 women. About 80 percent of all breast cancers are estrogen receptor-positive, in which cancer growth is fueled by estrogen.

12 Sep 2018

Scientists gain better understanding of tumor initiation and metastasis in colon cancer patients

Researchers from the University of Luxembourg have discovered a molecular mechanism that is responsible for the spread of cancer cells in the body and the development of metastases in patients with colon cancer. Their findings could help to develop treatments that inhibit tumor growth.

11 Sep 2018

Researchers develop the first interactive model of cell division

Researchers have developed an interactive atlas of human cell division, that shows the effect of protein misfolding on mitosis.

10 Sep 2018

Acute changes in extracellular matrix can trigger rapid change in cell’s metabolism

UCLA researchers have found that the extracellular matrix, the dense network of proteins and carbohydrates that surround a cell, can influence how cells move within the body by regulating their sugar consumption.

10 Sep 2018

NCCN updates Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets

Exelixis, Inc. today announced that the National Comprehensive Cancer Network updated its Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets.

7 Sep 2018

Researchers reveal how rapidly spreading ovarian cancer cells take the next steps

In nearly 80 percent of women with ovarian cancer, the disease has already spread to the omentum before it was diagnosed. Within the omentum - a large, energy-dense fat pad that covers the intestines - the cancer grows even faster.

7 Sep 2018

New diagnostic tool for difficult-to-detect cancers

A new diagnostic tool is expected to result in better treatment of cancer that is difficult to diagnose. The tool was developed by cancer researchers at Sahlgrenska Academy and doctors at the Sahlgrenska University Hospital, Sweden. Their study, which has been published in JCO Precision Oncology, started with a single cancer patient.

6 Sep 2018

Metastasis News and Research

Further Reading

Aggressive breast cancer hijacks normal protective physiological process to survive

Aspirin shown to prevent the spread of cancer

Researchers decipher antitumor mechanism of Amazonian plant in human cancer cells

New findings show importance of physical forces in tumor metastasis

Cancer Research UK, Keystone Symposia collaborate for cancer-related research

Researchers discover novel targeting agents to prevent cancer metastasis

Study: Second opinion can potentially change the diagnosis of breast cancer patients

VRK1 protein may enable cancer cells to colonize new areas of the body during metastasis

Phase 1 and 2 clinical trials of entrectinib drug in ROS1-positive NSCLC show promising results

CHMP provides positive opinion to Cabometyx for previously-treated patients with hepatocellular carcinoma

Ipsen receives approval from Health Canada for CABOMETYX tablets for treating renal cell carcinoma

Highly personalized approach may help immune cells to eliminate melanoma

Researchers design new medicine to treat highly aggressive pancreatic cancer

Researchers untangle mysteries of 'evil' protein in ER-positive breast cancer

Scientists gain better understanding of tumor initiation and metastasis in colon cancer patients

Researchers develop the first interactive model of cell division

Acute changes in extracellular matrix can trigger rapid change in cell’s metabolism

NCCN updates Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets

Researchers reveal how rapidly spreading ovarian cancer cells take the next steps

New diagnostic tool for difficult-to-detect cancers

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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