Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Lab-grown mini-placentas shed light on pre-eclampsia and pregnancy disorders

Scientists have grown 'mini-placentas' in the lab and used them to shed light on how the placenta develops and interacts with the inner lining of the womb – findings that could help scientists better understand and, in future, potentially treat pre-eclampsia.

17 Jan 2024

RBMX protein emerges as key player in cancer progression and immunotherapy response

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "Aberrant RBMX expression is relevant for cancer prognosis and immunotherapy response."

17 Jan 2024

CGRP antagonists and dietary changes show promise for migraine treatment

Review in "Medicina" explores advancements in migraine therapy, highlighting the role of CGRP antagonists and dietary interventions like ketogenic and low-glycemic diets in reducing migraine frequency and severity.

17 Jan 2024

TRPC3 emerges as key player in preventing damage from alcohol-associated liver disease

Excessive alcohol intake is strongly associated with alcohol-associated liver disease (ALD) which accounts for 25% and 30% of deaths from cirrhosis and hepatocellular carcinoma. Impairment of Ca2+ influx and Ca2+-mediated signaling in ALD suggests that Ca2+ channels are important in ALD pathological progression.

16 Jan 2024

Is AI the future of personalized hypertension risk assessment, diagnosis, and treatment?

Artificial intelligence (AI) applications for treating hypertension (HTN) and its comorbidities.

16 Jan 2024

GRK2: A new target for inhibiting macrophage infiltration and angiogenesis in rheumatoid arthritis

This new article publication from Acta Pharmaceutica Sinica B, discusses how GRK2 inhibits Flt-1+ macrophage infiltration and its proangiogenic properties in rheumatoid arthritis.

15 Jan 2024

Stromal cells may be useful in assessing prostate tumors' potential to spread

Non-cancerous cells called stromal cells, which are found in and around prostate tumors, may be useful in assessing these tumors' potential to spread, and may even be targets for future prostate cancer treatments, according to a study led by researchers at Weill Cornell Medicine.

12 Jan 2024

Groundbreaking study uncovers hundreds of genetic markers linked to insulin resistance

A genome-wide study of 402,398 individuals identifies 369 SNPs associated with insulin resistance, offering insights into metabolic diseases and potential therapeutic targets.

11 Jan 2024

Alzheimer's disease found to have five distinct subtypes

Researchers identified five distinct molecular subtypes of Alzheimer's disease using proteomic sequencing, suggesting personalized treatment approaches based on each subtype's unique genetic and pathological characteristics.

10 Jan 2024

MedUni Vienna researchers discover possible trigger of chronic inflammatory bowel disease

As the cause of chronic inflammatory bowel diseases (IBD) such as Crohn's disease or ulcerative colitis is not yet known, treatment for sufferers is currently aimed at alleviating the often agonizing symptoms.

10 Jan 2024

Protein linked to neurodegeneration turns out to be crucial for healthy brain function

Researchers have discovered that a protein called phosphorylated α-synuclein, which is associated with several neurodegenerative diseases such as Parkinson's disease and Lewy body dementia, is also involved in the normal processes of how neurons communicate with each other in a healthy brain.

9 Jan 2024

New Omicron subvariants test vaccine limits, reveal unique infection challenges

Study reveals that the Omicron subvariants BA.2.86 and FLip show unique mutations and infectivity profiles, with BA.2.86 being highly infectious and resistant to most conventional antibodies, underscoring the need for updated vaccines.

9 Jan 2024

MADE-up or real? Review debunks severity of mask-associated dry eye syndrome

A review in the journal Eye finds that prolonged face mask use during the COVID-19 pandemic may cause mild ocular irritation, but serious eye complications are unlikely.

9 Jan 2024

Infammasomes provide a therapeutic target against human diseases

The structure of inflammasomes and their role in diseases.

9 Jan 2024

New test detects Parkinson's disease before symptoms appear

In the development of Parkinson's disease (PD), the changes that will lead to neurodegeneration take place in the brain long before patients show any symptoms.

8 Jan 2024

Long COVID's hidden toll: How does post-exertional malaise affect skeletal muscles?

Study investigates the pathophysiology of post-exertional malaise in long COVID patients, revealing skeletal muscle changes, exercise capacity reduction, metabolic disturbances, and tissue alterations.

8 Jan 2024

Gut microbiota: the new frontier in Alzheimer’s disease research and therapy

The current evidence of the role of gut microbiota in Alzheimer’s disease (AD) pathogenesis.

8 Jan 2024

Researchers identify mechanism that causes gastrointestinal problems with cancer immunotherapy

Researchers at the University of Michigan Health Rogel Cancer Center have identified a mechanism that causes severe gastrointestinal problems with immune-based cancer treatment.

5 Jan 2024

Seizures may be responsible for some sudden deaths in children, study finds

In a study designed to better understand sudden, unexpected deaths in young children, which usually occur during sleep, researchers have identified brief seizures, accompanied by muscle convulsions, as a potential cause.

4 Jan 2024

Imbalances in folic acid and vitamin B12 can alter brain development in mice

Folate is a B vitamin and a necessary nutrient to prevent neural tube defects, such as spina bifida. Folic acid, a synthetic form of folate, has been added to vitamins, breakfast cereals and other products in the U.S. and more than 80 other countries to ensure pregnant women get adequate amounts.

4 Jan 2024

Pathology News and Research

Further Reading

Lab-grown mini-placentas shed light on pre-eclampsia and pregnancy disorders

RBMX protein emerges as key player in cancer progression and immunotherapy response

CGRP antagonists and dietary changes show promise for migraine treatment

TRPC3 emerges as key player in preventing damage from alcohol-associated liver disease

Is AI the future of personalized hypertension risk assessment, diagnosis, and treatment?

GRK2: A new target for inhibiting macrophage infiltration and angiogenesis in rheumatoid arthritis

Stromal cells may be useful in assessing prostate tumors' potential to spread

Groundbreaking study uncovers hundreds of genetic markers linked to insulin resistance

Alzheimer's disease found to have five distinct subtypes

MedUni Vienna researchers discover possible trigger of chronic inflammatory bowel disease

Protein linked to neurodegeneration turns out to be crucial for healthy brain function

New Omicron subvariants test vaccine limits, reveal unique infection challenges

MADE-up or real? Review debunks severity of mask-associated dry eye syndrome

Infammasomes provide a therapeutic target against human diseases

New test detects Parkinson's disease before symptoms appear

Long COVID's hidden toll: How does post-exertional malaise affect skeletal muscles?

Gut microbiota: the new frontier in Alzheimer’s disease research and therapy

Researchers identify mechanism that causes gastrointestinal problems with cancer immunotherapy

Seizures may be responsible for some sudden deaths in children, study finds

Imbalances in folic acid and vitamin B12 can alter brain development in mice

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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