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NEC, SomaLogic sign agreement to explore aptamer related businesses in life sciences, healthcare markets

NEC Corporation and privately held SomaLogic, Inc. announced today that they have signed an agreement to explore aptamer related businesses in the life sciences and healthcare markets. In addition, NEC announced that it has made an equity investment in SomaLogic in support of a long-term strategic relationship between the two companies.

31 Aug 2010

RXR-alpha protein helps to protect pigment cells from invasive melanoma: Research

New research on how skin cancer begins has identified adjacent cancer cells that scientists are calling "co-conspirators" in the genesis of melanoma, in findings that could someday hold the key to predicting, preventing and stopping this hard-to-treat cancer before it spreads.

31 Aug 2010

Jefferson scientists receive grant to study genetics of platelet gene expression

Scientists at Jefferson Medical College have received a four-year, $3 million National Institutes of Health grant funded by the National Heart, Lung and Blood Institute to study variations of platelet function, specifically, the genetics of platelet gene expression. The study aims to find data that can be translated into novel therapeutic strategies and develop better predictors of cardiovascular disease.

30 Aug 2010

Scientists identify genetic basis to determine severity of allergic asthma in experimental models

Scientists have identified a genetic basis for determining the severity of allergic asthma in experimental models of the disease.The study may help in the search for future therapeutic strategies to fight a growing medical problem that currently lacks effective treatments, researchers from Cincinnati Children's Hospital Medical Center report in the Aug. 29 Nature Immunology.

30 Aug 2010

Study finds BMI, thrombogenic factor increases cardiovascular risk

Although having a high body mass index (BMI) is a known risk factor for cardiovascular disease, researchers are only beginning to understand how BMI affects the physiological processes involved in the development of the disease. Now, a study of a subset of women in the Kronos Early Estrogen Prevention Study (KEEPS), suggests that as BMI increases, so do platelet reactivity and thrombogenic microvesicles and activated protein C in the blood-all of which contribute to the formation of atherothrombosis and associated cardiovascular events.

30 Aug 2010

New methodologies for protein measurement needed to address adulteration in infant formula and pet food

Recent incidents of adulteration involving infant formula, other milk products and pet food with the industrial chemical melamine revealed the weaknesses of current methods widely used across the domestic and global food industry for determining protein content in foods. The possible utility of alternative existing and emerging methods is the subject of a new paper published in Comprehensive Reviews in Food Science and Food Safety, a peer-reviewed journal of the Institute of Food Technologists (IFT).

27 Aug 2010

Second-hand smoke triggers complex inflammatory response

Second-hand smoke is associated with a number of diseases and conditions, including cancer, heart disease, and emphysema. It is an irritant to lung tissue and blood vessels, but the processes through which the body reacts to second-hand smoke comprise a mystery scientists are only beginning to unravel. Researchers at the University of Colorado-Denver are currently studying how second-hand smoke affects the lungs of rats, and so far it appears that second-hand smoke triggers a complex inflammatory response.

27 Aug 2010

Experimental drug PLX4032 holds promise against cancers with faulty BRAF gene

An experimental drug designed to treat cancers with a particular genetic fault has shown promising results in a small clinical trial.

27 Aug 2010

Researchers identify molecule to slow down dysfunctional immune response in hemorrhagic shock

Researchers have isolated a molecule, small enough to be used as a drug, that can shut down a dysfunctional immune response that causes deadly hemorrhagic shock, results in delayed death of heart attack patients, promotes rejection of transplanted organs and destroys joints in patients with rheumatoid arthritis, according to a paper published in Molecular Immunology.

27 Aug 2010

FDA denies accelerated approval of Genentech's trastuzumab-DM1 (T-DM1) BLA for metastatic breast cancer

In its review of the BLA, the FDA stated the T-DM1 trials did not meet the standard for accelerated approval because all available treatment choices approved for metastatic breast cancer, regardless of HER2 status, had not been exhausted in the study population.

27 Aug 2010

New book on fighting hair loss

World renowned hair loss expert, Dr. Larry Shapiro, announced the release of his new book, Fight Hair Loss and Win! and says that Elin Nordegren is not alone when it comes to hair loss as a result of stress. Shapiro says millions of women and men are experiencing the same and that heightened levels of stress, popular nutritional supplements, hormonal imbalances and many other unsuspecting factors are now linked to hair loss.

26 Aug 2010

Pathogens can delay entry into cells to ensure their survival, say researchers

Pathogens make themselves feel at home in the human body, invading cells and living off the plentiful amenities on offer. However, researchers at the Max Planck Institute for Infection Biology, Berlin, together with colleagues at Harvard University, reveal an opposite strategy used to ensure infection success. Pathogens can actually delay their entry into cells to ensure their survival.

26 Aug 2010

Research on myosin II protein can lead to novel treatment for memory disorders

Scientists from the Florida campus of The Scripps Research Institute have discovered a mechanism that plays a critical role in the formation of long-term memory. The findings shed substantial new light on aspects of how memory is formed, and could lead to novel treatments for memory disorders.

26 Aug 2010

Motor proteins play critical role in stabilization of long-term memories

Functioning much like gears in a machine, cellular motor proteins are critical to dynamic functions throughout the body, including muscle contraction, cell migration and cellular growth processes. Now, neuroscientists from UC Irvine and the Florida campus of The Scripps Research Institute report that motor proteins also play a critical role in the stabilization of long-term memories. The findings add an unexpected dimension to the story of how memories are encoded and suggest new targets for therapeutic interventions.

26 Aug 2010

Treating metastatic melanoma tumors with specific genetic signature shows promising results

Use of an experimental targeted drug to treat metastatic melanoma tumors with a specific genetic signature was successful in more than 80 percent of patients in a phase 1 clinical trial.

26 Aug 2010

PLX4032 therapy results in tumor shrinkage in metastatic melanoma patients

A multicenter study has concluded that treatment with a new targeted therapy called PLX4032 (also called RG7204) resulted in significant tumor shrinkage in 80 percent of patients with advanced melanoma.

26 Aug 2010

Critical mechanistic link between mutant protein and disease pathogenesis in ALS uncovered

New research uncovers what may be a primary neuron-damaging insult that occurs in an inherited form of a devastating neurodegenerative disorder. The study, published by Cell Press in the August 26th issue of the journal Neuron, describes a critical mechanistic link between a mutant protein and disease pathogenesis in an animal model of amyotrophic lateral sclerosis (ALS).

26 Aug 2010

Atherotech Diagnostics to exhibit VAP Cholesterol Test at NLA Summer 2010 Clinical Update

Atherotech Diagnostics Lab will exhibit its VAP Cholesterol Test in booth 105 at the National Lipid Association (NLA) Summer 2010 Clinical Lipid Update.

26 Aug 2010

FibroGen announces study results of recombinant human type III collagen in corneal damage

FibroGen, Inc., today announced results of a 2-year clinical study demonstrating that surgical implantation of biosynthetic corneas formulated with the company's proprietary recombinant human type III collagen (rhCIII) restored vision and promoted nerve regeneration (restoring sensitivity) in patients who had corneal damage and significant vision loss.

26 Aug 2010

CFHR5 nephropathy linked to genetic mutation in innate immune system

A rare form of kidney disease linked to a genetic mutation in the innate immune system has been identified by researchers funded by the Wellcome Trust and the Medical Research Council.

26 Aug 2010

G Protein News and Research

NEC, SomaLogic sign agreement to explore aptamer related businesses in life sciences, healthcare markets

RXR-alpha protein helps to protect pigment cells from invasive melanoma: Research

Jefferson scientists receive grant to study genetics of platelet gene expression

Scientists identify genetic basis to determine severity of allergic asthma in experimental models

Study finds BMI, thrombogenic factor increases cardiovascular risk

New methodologies for protein measurement needed to address adulteration in infant formula and pet food

Second-hand smoke triggers complex inflammatory response

Experimental drug PLX4032 holds promise against cancers with faulty BRAF gene

Researchers identify molecule to slow down dysfunctional immune response in hemorrhagic shock

FDA denies accelerated approval of Genentech's trastuzumab-DM1 (T-DM1) BLA for metastatic breast cancer

New book on fighting hair loss

Pathogens can delay entry into cells to ensure their survival, say researchers

Research on myosin II protein can lead to novel treatment for memory disorders

Motor proteins play critical role in stabilization of long-term memories

Treating metastatic melanoma tumors with specific genetic signature shows promising results

PLX4032 therapy results in tumor shrinkage in metastatic melanoma patients

Critical mechanistic link between mutant protein and disease pathogenesis in ALS uncovered

Atherotech Diagnostics to exhibit VAP Cholesterol Test at NLA Summer 2010 Clinical Update

FibroGen announces study results of recombinant human type III collagen in corneal damage

CFHR5 nephropathy linked to genetic mutation in innate immune system

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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