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GSK, Aeras to advance clinical development of TB vaccine

Aeras announces that it has signed an agreement with GlaxoSmithKline Vaccines, S.A. (GSK) to jointly advance the clinical development of an investigational tuberculosis (TB) vaccine containing GSK's proprietary M72 antigen and AS01E adjuvant.

10 Oct 2012

Study identifies cellular adhesion molecules key to cancer metastasis

Although tumor metastasis causes about 90 percent of cancer deaths, the exact mechanism that allows cancer cells to spread from one part of the body to another is not well understood. One key question is how tumor cells detach from the structural elements that normally hold tissues in place, then reattach themselves in a new site.

10 Oct 2012

Viewpoints: David Brooks' praise for Ryan plan; Medicaid overlooked in presidential debate; Romney proposal effective for pre-existing conditions

In Thursday night's debate, Vice President Joe Biden will almost certainly go after Representative Paul Ryan's Medicare plan. And why shouldn't he? It's unpopular. But I'd like to make a case for that plan. It's the best thing the Romney-Ryan campaign has going for it.

10 Oct 2012

American Gastroenterological Association launches new electronic offerings

In order to best meet the needs of members, the American Gastroenterological Association has launched new electronic offerings to make it easier for busy health-care professionals to stay abreast of the latest research and news in gastroenterology while on the go.

10 Oct 2012

RMND1 gene mutations responsible for severe neurodegenerative disorders

Scientists at the Montreal Neurological Institute and Hospital - The Neuro, McGill University working with a team at Oxford University have uncovered the genetic defect underlying a group of rare genetic disorders.

10 Oct 2012

Aspirin associated with reduced risk of serious ovarian cancer

New research shows that women who regularly use pain relief medications, particularly aspirin, have a decreased risk of serious ovarian cancer—an aggressive carcinoma affecting the surface of the ovary.

10 Oct 2012

Roundup: Labor activist's work for Blue Shield raises conflict concerns; R.I. to mandate flu shots for health workers; Minn. safety net hospitals brace for cuts

At a time when public-sector unions across the country are fighting to hold on to generous retirement and health benefits, one of the loudest voices standing up for their rights is Dave Low. A longtime labor activist, Low carries considerable clout as executive director of the California School Employees Assn., a 215,000-member union that represents bus drivers, custodians and other school workers.

10 Oct 2012

CT technique could improve COPD classification

The parametric response map technique can be used in chronic obstructive pulmonary disease to distinguish between disease subtypes, say US researchers.

9 Oct 2012

Transfused blood age does not impact outcomes in premature babies

Using fresh red blood cells for premature babies who need blood transfusions does not improve outcomes over use of standard blood bank donations, show study findings published in JAMA.

9 Oct 2012

High personality disorder comorbidity rates identified in anxiety

A meta-analysis covering 30 years of research has identified high rates of comorbid personality disorders across a number of anxiety disorder subtypes.

9 Oct 2012

PUFA levels reduced in schizophrenia patients

Results from a systematic review and meta-analysis show that erythrocyte membrane concentrations of certain polyunsaturated fatty acids are reduced in the brains of people with schizophrenia.

9 Oct 2012

Kynurenic acid levels increased in bipolar patients with psychotic features

Bipolar disorder patients with a history of psychotic features have higher cerebrospinal fluid concentrations of kynurenic acid (KYNA) than those without such features, research shows.

9 Oct 2012

Physical activity fights cognitive dysfunction after stroke

A program of aerobic and resistance training helps patients overcome cognitive deficits occurring as a result of stroke, shows research presented at the 3rd Canadian Stroke Congress in Calgary, Alberta.

9 Oct 2012

DBP ‘remains relevant’ in stroke risk assessment

A large study has shed light on the relationship of systolic and diastolic blood pressure with stroke risk as people age.

9 Oct 2012

MRI method ‘cuts breast cancer false‑positives’

Assessing apparent diffusion coefficients during dynamic contrast-enhanced magnetic resonance imaging may reduce the number of avoidable false‑positive breast cancer results and unnecessary biopsies, show findings published in Radiology.

9 Oct 2012

First Edition: October 9, 2012

Today's headlines include reports about how a new poll indicates GOP presidential hopeful Mitt Romney gained a significant bounce from last week's debate performance.

9 Oct 2012

Johns Hopkins joins API’s Actimab-A Phase I/II trial in acute myeloid leukemia

Actinium Pharmaceuticals, Inc. (API), a biopharmaceutical company that develops innovative targeted payload immunotherapeutics, announced that Johns Hopkins University School of Medicine in Baltimore, MD has joined the Company's ongoing Phase I/II trial in newly diagnosed elderly patients with acute myeloid leukemia (AML).

9 Oct 2012

Innovative treatments can lead to functional improvements in patients with SCIs

A series of rehabilitation studies published in the September 2012 issue of the Archives of Physical Medicine & Rehabilitation demonstrate that innovative treatments for individuals with spinal cord injuries can lead to significant functional improvements in patients and a higher quality of life.

9 Oct 2012

Lilly announces detailed results from solanezumab Phase 3 trials on Alzheimer's

Eli Lilly and Company today announced its detailed results for the Phase 3, double-blind, placebo-controlled EXPEDITION studies in patients with mild-to-moderate Alzheimer's disease.

9 Oct 2012

Nurses accurate barometers of hospital quality: Study

A new study from the University of Pennsylvania School of Nursing affirms a straightforward premise: Nurses are accurate barometers of hospital quality.

9 Oct 2012