Immune System News and Research

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New study explores how bacterial pathogen Yersinia tries to outsmart immune cell responses

A new study led by scientists at the University of Pennsylvania School of Veterinary Medicine has painted a clearer picture of the delicate arms race between the human immune system and a pathogen that seeks to infect and kill human cells.

6 May 2014

Bristol-Myers Squibb to present new immunotherapy study data at ASCO Annual Meeting

Bristol-Myers Squibb Company today announced that new data from studies investigating its immunotherapies in adjuvant and advanced melanoma, non-small cell lung cancer (NSCLC) and metastatic renal cell carcinoma (mRCC) will be presented at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago from May 30-June 3.

6 May 2014

BeiGene receives $5M from Merck to develop BGB-283 BRAF inhibitor

BeiGene (Beijing), Co., Ltd., an innovative oncology company focused on developing targeted and immune-oncology therapeutics, today announced the achievement of a clinical milestone in the company's collaboration with Merck Serono, the biopharmaceutical division of Merck, Darmstadt, Germany, for BGB-283, a second-generation BRAF inhibitor candidate currently in Phase 1 development.

6 May 2014

Study links nerve damage after hip surgery to inflammatory neuropathy

A recent Mayo Clinic Proceedings article links some nerve damage after hip surgery to inflammatory neuropathy. Historically, nerve damage from hip surgery has been attributed to mechanical factors caused by anesthesiologists or surgeons, such as positioning of the patient during surgery or direct surgical injury of the nerves.

6 May 2014

UH biomedical engineer receives ALR grant to study cause of lupus nephritis

In the U.S. alone, more than 1.5 million people have lupus, a chronic autoimmune disease in which the immune system turns against itself, attacking a person's healthy tissue, cells and organs. The symptoms can range from debilitating pain and fatigue to organ failure.

6 May 2014

BrightFocus Foundation honors 5 outstanding scientists in fields of macular degeneration, glaucoma

The BrightFocus Foundation today honored five outstanding scientists in the fields of macular degeneration and glaucoma, presenting them with named research awards at an event during the annual meeting of the Association for Research in Vision and Ophthalmology.

6 May 2014

New research reveals that eczema may lower skin cancer risk

Eczema caused by defects in the skin could reduce the risk of developing skin cancer, according to new research by King's College London. The immune response triggered by eczema could help prevent tumour formation by shedding potentially cancerous cells from the skin.

6 May 2014

Scientists develop bone marrow-on-a-chip to test effects of new drugs, toxic agents on bone marrow

The latest organ-on-a-chip from Harvard's Wyss Institute for Biologically Inspired Engineering reproduces the structure, functions and cellular make-up of bone marrow, a complex tissue that until now could only be studied intact in living animals, Institute researchers report in the May 4, 2014, online issue of Nature Methods.

6 May 2014

Psychiatrist wins Kempf Fund Award for Research Development in Psychobiological Psychiatry

Dr. Peter F. Buckley, a psychiatrist specializing in schizophrenia and Dean of the Medical College of Georgia at Georgia Regents University, is the 2014 winner of the Kempf Fund Award for Research Development in Psychobiological Psychiatry from the American Psychiatric Association.

6 May 2014

Extremely premature babies should not be given drug to prevent fatal fungal infection

In most circumstances, extremely premature babies should not be given a drug to prevent a potentially fatal fungal infection, according to findings by a Duke Medicine-led research team.

5 May 2014

New technique to examine how proteins interact at level of single HIV viral particle

An interdisciplinary team of scientists from KU Leuven in Belgium has developed a new technique to examine how proteins interact with each other at the level of a single HIV viral particle.

5 May 2014

Research provides definitive evidence of safety of Tdap immunization during pregnancy

A preliminary study finds that receipt of the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine in the third trimester of pregnancy did not increase the risk of adverse events for the mother or infant, according to a study in the May 7 issue of JAMA, a theme issue on child health.

5 May 2014

Puzzle in breast cancer solved

In a new study published in Cell Reports, scientists at the Fred Hutchinson Cancer Research Center demonstrate that mice lacking one copy of a gene called CTCF have abnormal DNA methylation and are markedly predisposed to cancer.

5 May 2014

Higher sleep efficiency in women with advanced breast cancer is associated with lower mortality

A new study reports that sleep efficiency, a ratio of time asleep to time spent in bed, is predictive of survival time for women with advanced breast cancer.

5 May 2014

UAMS receives $1.8M grant to lead new treatments for herpes viruses and cancers

A surprise discovery that could lead to new treatments for herpes viruses that infect more than 90 percent of the world's adult population has led to a $1.8 million grant to the University of Arkansas for Medical Sciences (UAMS) from the National Cancer Institute (NCI) at the National Institutes of Health (NIH).

5 May 2014

Johns Hopkins biochemists figure out HIV-fighting activity of enzyme

Johns Hopkins biochemists have figured out what is needed to activate and sustain the virus-fighting activity of an enzyme found in CD4+ T cells, the human immune cells infected by HIV. The discovery could launch a more effective strategy for preventing the spread of HIV in the body with drugs targeting this enzyme, they say.

2 May 2014

Study provides insight into effects of interleukin-27 in regulatory T-cell biology, physiological functions of IL-27

In a new report published in the Journal of Leukocyte Biology, scientists lay the groundwork for the development of novel tumor therapies that may help rid the body of cancer by inhibiting the recruitment of a specific suppressive immune cell type called "regulatory T-cells." The approach described in the report shows that an immune molecule, called interleukin-27, promotes the recruitment of regulatory T-cells.

2 May 2014

TSRI scientists identify molecular pathways that resveratrol uses to achieve beneficial action

Resveratrol has been much in the news as the component of grapes and red wine associated with reducing “bad cholesterol,” heart disease and some types of cancer. Also found in blueberries, cranberries, mulberries, peanuts and pistachios, resveratrol is associated with beneficial health effects in aging, inflammation and metabolism.

30 Apr 2014

Hormone disrupting pollutants affecting the development of wild birds along urban rivers

New research indicates that hormone disrupting pollutants are affecting the health and development of wild birds nesting along the urban rivers of South Wales.

30 Apr 2014

Gokhan S. Hotamisligil named recipient of the 9th Danone International Prize for Nutrition

Danone Institute International announced today that prominent scientist Gokhan S. Hotamisligil, MD, PhD, is the recipient of the 9th Danone International Prize for Nutrition for his outstanding research in immunology and metabolic diseases.

30 Apr 2014

Immune System News and Research

New study explores how bacterial pathogen Yersinia tries to outsmart immune cell responses

Bristol-Myers Squibb to present new immunotherapy study data at ASCO Annual Meeting

BeiGene receives $5M from Merck to develop BGB-283 BRAF inhibitor

Study links nerve damage after hip surgery to inflammatory neuropathy

UH biomedical engineer receives ALR grant to study cause of lupus nephritis

BrightFocus Foundation honors 5 outstanding scientists in fields of macular degeneration, glaucoma

New research reveals that eczema may lower skin cancer risk

Scientists develop bone marrow-on-a-chip to test effects of new drugs, toxic agents on bone marrow

Psychiatrist wins Kempf Fund Award for Research Development in Psychobiological Psychiatry

Extremely premature babies should not be given drug to prevent fatal fungal infection

New technique to examine how proteins interact at level of single HIV viral particle

Research provides definitive evidence of safety of Tdap immunization during pregnancy

Puzzle in breast cancer solved

Higher sleep efficiency in women with advanced breast cancer is associated with lower mortality

UAMS receives $1.8M grant to lead new treatments for herpes viruses and cancers

Johns Hopkins biochemists figure out HIV-fighting activity of enzyme

Study provides insight into effects of interleukin-27 in regulatory T-cell biology, physiological functions of IL-27

TSRI scientists identify molecular pathways that resveratrol uses to achieve beneficial action

Hormone disrupting pollutants affecting the development of wild birds along urban rivers

Gokhan S. Hotamisligil named recipient of the 9th Danone International Prize for Nutrition

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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How Omics Technologies Are Transforming Biological Research and Drug Discovery

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