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C-Path awarded FDA grant to establish Rare Disease Clinical Outcome Assessment Consortium

The U.S. Food and Drug Administration's Center for Drug Evaluation and Research has funded a cooperative agreement to establish a Rare Disease Clinical Outcome Assessment Consortium.

21 Mar 2020

As coronavirus spreads widely, millions of older Americans live in counties with no ICU beds

More than half the counties in America have no intensive care beds, posing a particular danger for more than 7 million people who are age 60 and up - older patients who face the highest risk of serious illness or death from the rapid spread of COVID-19, a Kaiser Health News data analysis shows.

20 Mar 2020

Immunotherapy treatment shows promise for some patients with advanced rare cancers

A study conducted by researchers at The University of Texas MD Anderson Cancer Center demonstrated acceptable toxicity and anti-tumor activity in patients with four types of advanced, hard-to-treat rare cancers.

20 Mar 2020

Research provides better understanding of how tremor happens

Researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital have improved our understanding of how tremor -- the most common movement disorder -- happens, opening the possibility of novel therapies for this condition.

19 Mar 2020

Diet affects sperm and the health of offspring

A new study published in the journal Molecular Cell, in March 2020, reports that parental diet is a crucial factor in the future metabolic health of the offspring.

19 Mar 2020

Some children may become seriously ill with coronavirus, experts warn

Evidence shows that coronavirus disease (COVID-19) most often affects older adults, who are 60 years old or more, and those with underlying medical conditions. But a new study has shown that several children in China had developed severe or critical conditions, with one child dying from COVID-19.

19 Mar 2020

Staying positive and managing stress amid the coronavirus crisis

With all the news about the coronavirus disease (COVID-19) pandemic circulating online, stress levels are rising. Most countries that are shaken by the virus outbreak have imposed lockdowns, in attempts to curb the disease spread.

19 Mar 2020

Study offers new insight into genetic alterations associated with osteosarcoma

A study by researchers at the National Cancer Institute, part of the National Institutes of Health, offers new insight into genetic alterations associated with osteosarcoma, the most common cancerous bone tumor of children and adolescents.

19 Mar 2020

Researchers uncover molecular events underlying paternal diet-induced metabolic disorders in children

When parents eat low-protein or high-fat diets it can lead to metabolic disorders in their adult offspring. Now, an international team led by researchers at the RIKEN Cluster for Pioneering Research have identified a key player and the molecular events underlying this phenomenon in mice.

19 Mar 2020

Problems with processing visual impressions may be the real root of children’s problems

Visual processing is about how the brain perceives and processes the impressions of the eyes. Problems with processing visual impressions can also impact a variety of other skills.

19 Mar 2020

Study helps predict which ovarian cancer patients will not benefit from immune-PARP combo

In patients with advanced ovarian cancer, a combination of drugs known as immune checkpoint inhibitors and PARP inhibitors can produce powerful remissions, clinical trials have shown, but up until now investigators haven't been able to predict which patients won't benefit from the treatment and should explore other options.

19 Mar 2020

Obese children more prone to anxiety, depression and shortening of life

Two studies published in the journals PLOS Medicine and BMC Medicine in March 2020 show that obesity in childhood is linked to a higher risk of future anxiety, depression, and death in early adult life compared to children in the general population. This could shape efforts to detect specific risk factors that predispose children to obesity and thus prevent it.

18 Mar 2020

A view from the front lines of California’s COVID-19 battle

On Tuesday, Dr. Jeanne Noble devoted time between patient visits to hanging clear 2-gallon plastic bags at each of her colleagues' workstations.

18 Mar 2020

Drug from scorpion venom could offer hope for children with fetal alcohol spectrum disorder

A research team led by Children's National Hospital faculty was able to "rescue" a pre-clinical model of fetal alcohol spectrum disorder in juvenile models, reversing motor skill deficits with the help of a novel drug derived from scorpion venom.

18 Mar 2020

Bacterial extracellular vesicles could combat antibiotic resistance

Children's National Hospital researchers for the first time have isolated bacterial extracellular vesicles from the blood of healthy donors, a critical step to better understanding the way gut bacteria communicate with the rest of the body via the bloodstream.

18 Mar 2020

Take a deep breath: Making risk-based decisions in the coronavirus era

Just last week, it seemed OK to have lunch out or maybe meet up with friends for a game of pickup soccer.

18 Mar 2020

High iron levels in lung increase severity of asthma

A new study published in the European Respiratory Journal in March 2020 reports that the accumulation of iron in the cells of the lung exacerbates asthma symptoms and reduces lung function.

17 Mar 2020

Prestigious journal lauds innovative NICU training

"Fires, tornadoes and other natural disasters are outside of our team's control. But it is within our team's control to train neonatal intensive care unit staff to master this necessary skill," says Lisa Zell, BSN, a clinical educator at Children's National Hospital.

17 Mar 2020

AI-powered, smart insole turns any shoe into portable gait-analysis laboratory

Researchers at Stevens Institute of Technology have developed an AI-powered, smart insole that instantly turns any shoe into a portable gait-analysis laboratory.

17 Mar 2020

U.S. issues coronavirus guidelines for the next 15 days

To stem the coronavirus disease (COVID-19) outbreak in the United States, President Donald Trump has issued coronavirus guidelines, which are in place for the next 15 days.

17 Mar 2020