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Combination of cystic fibrosis drugs found to be safe and effective in children aged 2-5 years

An open label Phase 3 study conducted at Ann & Robert H. Lurie Children's Hospital of Chicago and other centers established that a combination of cystic fibrosis drugs lumacaftor and ivacaftor is safe and effective in children aged 2-5 years, whose disease is caused by two copies of F508del-CFTR gene mutation - the most common and severe form of cystic fibrosis.

25 Jan 2019

Standard method for ranking liver transplant waitlists may not prioritize the sickest candidates

A new study has uncovered that the standard method for ranking patients on the waitlist for lifesaving liver transplantation may not prioritize some of the sickest candidates for the top of the list.

25 Jan 2019

World-class scientific leaders join Crick boards

Two world-class scientific leaders have been appointed to help govern the Crick’s institutional and scientific strategy, with neuroscientist Mene Pangalos joining the Board of Trustees and biochemist Elena Conti joining the Scientific Advisory Board.

From The Francis Crick Institute 24 Jan 2019

African scientists to build research capacity in African countries, develop ongoing scientific partnerships

Ten African scientists have been selected for training at the National Institutes of Health as part of a new fellowship program to build research capacity in African countries and develop ongoing scientific partnerships.

24 Jan 2019

FDA grants clearance to Hologic’s assay for detection of common sexually transmitted infections

Hologic, Inc. announced today that the U.S. Food and Drug Administration (FDA) has granted clearance for its Aptima Mycoplasma genitalium assay, the first and only FDA-cleared test to detect this under-recognized but increasingly common sexually transmitted infection (STI).

23 Jan 2019

TGen identifies polio-like virus as potential cause of Acute Flaccid Myelitis outbreak

The Translational Genomics Research Institute, an affiliate of City of Hope, has identified a polio-like virus as a potential cause of an outbreak of a disease known as Acute Flaccid Myelitis (AFM), a crippling condition that causes muscle weakness and paralysis usually among children.

23 Jan 2019

Human 'common cold' virus continues to spread in wild chimpanzees

Less than two years after the first report of wild chimpanzees in Uganda dying as a result of a human "common cold" virus, a new study has identified two other respiratory viruses of human origin in chimpanzee groups in the same forest.

22 Jan 2019

WHO identifies non-communicable diseases as major threat to human health

Second on the list are non-communicable diseases including cancer, heart disease, stroke, diabetes etc. The WHO report states that around 70 percent of the deaths are caused by these non-communicable diseases.

21 Jan 2019

Study to investigate new targeted oral treatments for severe asthma

A £2.68 million study to investigate the effective use of antibiotics to treat certain types of severe asthma is being spearheaded by researchers in Leicester.

21 Jan 2019

Study takes a step closer to understanding the body's response to opioid painkillers

Researchers have taken a step closer to understanding the body's response to opioid painkillers such as morphine and fentanyl, which could lead to the development of safer opioid drugs.

21 Jan 2019

Antiepileptic drug use by people with Alzheimer's disease linked to accumulation of hospital days

People with Alzheimer's disease who used antiepileptic drugs had a higher number of accumulated hospital days than people with Alzheimer's disease who did not use antiepileptics, according to a new study from the University of Eastern Finland.

21 Jan 2019

Rising air pollution linked with increased ER visits for breathing problems

As levels of ozone and fine particulate pollution (PM2.5) rise, more patients end up in the ER with breathing problems, according to the largest U.S. study of air pollution and respiratory emergency room visits of patients of all ages.

18 Jan 2019

DZIF scientists reveal problems with available diagnostics for Zika and chikungunya virus

Millions of people have contracted Zika and chikungunya virus infections since the outbreaks that have been striking Latin America since 2013. Particularly Zika-related malformations in newborns warrant reliable diagnostics.

18 Jan 2019

FDA approves generic drug for treating focal seizures

The U.S. Food and Drug Administration approved the first generic version of Sabril (vigabatrin) 500 mg tablets for treating complex partial seizures, also called focal seizures, as an adjunctive therapy (given with another primary treatment) in patients 10 years and older who have responded inadequately to several alternative (refractory) treatments.

16 Jan 2019

Childhood body composition may play a role in future respiratory health

How well we breathe as adults may depend on the amount of fat mass and lean body mass, or muscle, we have as children, according to new research published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.

16 Jan 2019

Researchers reveal how fasting leads to better overall health

In a University of California, Irvine-led study, researchers found evidence that fasting affects circadian clocks in the liver and skeletal muscle, causing them to rewire their metabolism, which can ultimately lead to improved health and protection against aging-associated diseases.

16 Jan 2019

New bacteria discovered in the blood of human patients

Two new species of bacteria have been found in the blood of patients in China.

10 Jan 2019

Specific respiratory microbiome may be linked to influenza susceptibility, finds study

Specific respiratory microbiome communities may be linked to influenza susceptibility, according to a study published January 9, 2019 in the open-access journal PLOS ONE by Betsy Foxman from the University of Michigan, USA, and colleagues

10 Jan 2019

Study finds correlation between perceived maternal stress and overweight children

Overweight is unhealthy. Yet more and more people in Germany are overweight, particularly children. As part of the LiNA mother-child study coordinated by the Helmholtz Centre for Environmental Research, researchers were able to identify mother's perceived stress during the first year of the child's life as a risk factor for developing overweight in infancy.

9 Jan 2019

Penn Highlands becomes first in region to offer bronchoscopic lung volume reduction

Penn Highlands Healthcare is the first medical facility in the region to offer bronchoscopic lung volume reduction using the first lung valve approved by the U.S. Food and Drug Administration for helping emphysema patients breathe easier without major surgery.

9 Jan 2019

Respiratory News and Research

Combination of cystic fibrosis drugs found to be safe and effective in children aged 2-5 years

Standard method for ranking liver transplant waitlists may not prioritize the sickest candidates

World-class scientific leaders join Crick boards

African scientists to build research capacity in African countries, develop ongoing scientific partnerships

FDA grants clearance to Hologic’s assay for detection of common sexually transmitted infections

TGen identifies polio-like virus as potential cause of Acute Flaccid Myelitis outbreak

Human 'common cold' virus continues to spread in wild chimpanzees

WHO identifies non-communicable diseases as major threat to human health

Study to investigate new targeted oral treatments for severe asthma

Study takes a step closer to understanding the body's response to opioid painkillers

Antiepileptic drug use by people with Alzheimer's disease linked to accumulation of hospital days

Rising air pollution linked with increased ER visits for breathing problems

DZIF scientists reveal problems with available diagnostics for Zika and chikungunya virus

FDA approves generic drug for treating focal seizures

Childhood body composition may play a role in future respiratory health

Researchers reveal how fasting leads to better overall health

New bacteria discovered in the blood of human patients

Specific respiratory microbiome may be linked to influenza susceptibility, finds study

Study finds correlation between perceived maternal stress and overweight children

Penn Highlands becomes first in region to offer bronchoscopic lung volume reduction

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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