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Injured veteran almost back to normal after penis and scrotum transplant

An interesting letter in the New England Journal of Medicine on November 7, 2019, describes the successful outcome at one year of a rare genital transplant in a young war veteran who lost most of the lower part of the abdominal wall, the scrotum and both testes, and both legs below the knee, to a bomb blast.

10 Nov 2019

Skin-to-skin contact between mother and baby after C-section has risks

It was widely accepted that putting the newborn baby on the mother’s chest promotes skin-to-skin contact and bonding between the two who share the common experience of birth, and enhances the chances of successful breastfeeding, after a Cesarean section. However, from the viewpoint of anesthesiologists, who oversee the critical part of keeping the mother pain-free yet healthy during the surgical procedure, this introduces unnecessary risks.

10 Nov 2019

Dengue vaccine from Takeda shows promise

Officials have confirmed the initial success with trials of Dengue vaccine. Dengue, a viral disease borne by mosquitoes is considered to be one of the top ten health threats says the world Health Organization (WHO). Since the beginning of the outbreaks and the hundreds of deaths due to this infection, researchers have been on the lookout for vaccines to prevent this infection.

10 Nov 2019

Additional medications needed to control the symptoms of juvenile idiopathic arthritis

According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, there is a profound ongoing need for additional medications to control the signs and symptoms of juvenile idiopathic arthritis, despite the availability of several approved biologic disease-modifying antirheumatic drugs (biologics).

10 Nov 2019

Study pinpoints new weapon to fight against deadly microbes

Researchers at Monash University have gained insights into how nanoparticles could be used to identify the presence of invasive and sometimes deadly microbes, and deliver targeted treatments more effectively.

10 Nov 2019

New method for identifying 'biomarkers' of drug response in triple-negative breast cancer cell lines

Triple-negative breast cancer is an aggressive cancer, one that's likely to recur and to metastasize.

10 Nov 2019

Study finds fewer new cases of HCV in HIV-negative men who have sex with PrEP-using men

Data from a new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found fewer new cases of hepatitis C infection (commonly called HCV), despite very high rates of other sexually-transmitted infections, in HIV-negative men who have sex with men who take pre-exposure prophylaxis (PrEP) treatments.

10 Nov 2019

Study finds lower levels of liver decompensation in pregnant women with cirrhosis

Data from a new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases and funded by the AASLD Foundation – found that less than two percent of pregnant women with cirrhosis had liver decompensation within one year of delivery, and their odds of decompensation is much lower than non-pregnant women with cirrhosis.

10 Nov 2019

HCC and cirrhosis-related deaths may be prevented by lifestyle modifications

Data from a new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found that a substantial burden of hepatocellular carcinoma and cirrhosis-related deaths may be prevented by lifestyle modifications to diet, alcohol use and exercise.

10 Nov 2019

Botanical product kratom may cause liver toxicity and injury, study finds

Data from a new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found that kratom, a popular and widely available product, may cause liver toxicity and severe liver injury.

10 Nov 2019

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

For the first time, a study led by researchers at Helmholtz Zentrum München and the German Center for Diabetes Research shows how glucocorticoid hormones, such as cortisol, control sugar and fat levels differently during day and night, feeding and fasting, rest and activity, over the course of 24 hours.

10 Nov 2019

Preclinical data on new drug combination to treat neuroblastoma published

Neuroblastoma is the most common cancer outside of the brain in infants and young children and often fails to respond to therapy. Though it can appear in several areas of the body, it commonly develops as a solid tumor most frequently found in or adjacent to the adrenal glands, which sit atop the kidneys.

10 Nov 2019

Glutamine-blocking compound slows cancer growth, unleashes anti-tumor immune response

A compound developed by Johns Hopkins researchers that blocks glutamine metabolism can slow tumor growth, alter the tumor microenvironment and promote the production of durable and highly active anti-tumor T cells.

10 Nov 2019

Simulation-based approach to target epilepsy enters into clinical trial

In what represents a major milestone on the path to clinical application, a novel method to improve outcomes of Epilepsy surgery has now received approval for clinical testing in 13 French hospitals.

9 Nov 2019

Investigators use the power of computation to build better targeted drug therapy

Antibody drug conjugates (ADCs) -- cancer drugs that are designed to target and destroy cancerous tissue while leaving healthy cells intact -- represent a long sought-after advancement in cancer therapy.

8 Nov 2019

Combination therapy shows promise for transplanting HCV-infected organs

Data from a new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found that combination therapy with direct-acting antivirals (DAAs) and ezetimibe.

8 Nov 2019

UK to be transformed into global hub for next-generation radiotherapy research

The UK will be transformed into a global hub for radiotherapy research, pioneering the use of the latest techniques such as FLASH radiotherapy and artificial intelligence, with a new £56 million research network announced by Cancer Research UK today (Monday).

8 Nov 2019

Drugs News and Research

Injured veteran almost back to normal after penis and scrotum transplant

Skin-to-skin contact between mother and baby after C-section has risks

Dengue vaccine from Takeda shows promise

Additional medications needed to control the symptoms of juvenile idiopathic arthritis

Study pinpoints new weapon to fight against deadly microbes

New method for identifying 'biomarkers' of drug response in triple-negative breast cancer cell lines

Study finds fewer new cases of HCV in HIV-negative men who have sex with PrEP-using men

Study finds lower levels of liver decompensation in pregnant women with cirrhosis

HCC and cirrhosis-related deaths may be prevented by lifestyle modifications

Botanical product kratom may cause liver toxicity and injury, study finds

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

Preclinical data on new drug combination to treat neuroblastoma published

Glutamine-blocking compound slows cancer growth, unleashes anti-tumor immune response

Simulation-based approach to target epilepsy enters into clinical trial

Investigators use the power of computation to build better targeted drug therapy

Combination therapy shows promise for transplanting HCV-infected organs

UK to be transformed into global hub for next-generation radiotherapy research

Could improving the brain’s waste disposal system help prevent Parkinson’s and Alzheimer’s?

Extending Medicare coverage of transplant drugs would benefit patients, reduce healthcare costs

DuPont to highlight innovative solutions for future pharma challenges at AAPS: PharmSci 360

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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