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Review focuses on aging in ethnic skin

The population in the United States is expected to become increasingly older, with estimates indicating that by the year 2030, nearly 40 percent of Americans will be over the age of 65.

26 Jul 2019

Discovery of new liver cell could make liver transplants redundant

Researchers at King's College London have used single cell RNA sequencing to identify a type of cell that may be able to regenerate liver tissue, treating liver failure without the need for transplants.

26 Jul 2019

New drug data release set to power genetic research into cancer treatment

This week (25 July) the Genomics of Drug Sensitivity in Cancer project has released the results of four years of intense data gathering and exploration which will power genetic research into cancer treatment worldwide.

26 Jul 2019

Scientists investigate how fungus interacts with bacteria to trigger Crohn's disease

Scientists have known that bacteria in the gut, along with environmental and genetic factors, contribute to the debilitating intestinal ailment of Crohn's disease.

26 Jul 2019

Genetic mutations link rare skin disorder and non-alcoholic fatty liver disease

Fatty liver disease is often associated with alcoholism, but more than a third of Americans have fatty livers despite moderate or absent alcohol consumption.

25 Jul 2019

'Junk' DNA mutations highly significant in autism and stroke

Non-coding DNA, junk DNA, genetic dark matter – these are all names for the 98% of DNA that doesn’t directly code for proteins but is crucial in regulating protein synthesis. This is now the focus of a large new study published in the journal Nature Genetics.

25 Jul 2019

New breast cancer drug identified as a potential therapy for glioblastoma

The Ivy Brain Tumor Center at the Barrow Neurological Institute, has released the results of its recent Phase 0 clinical trial of the breast cancer drug ribociclib (Kisqali) for the treatment of recurrent glioblastoma.

25 Jul 2019

Research links inherited BRCA2 mutations with increased risk of childhood lymphoma

A report from St. Jude Children's Research Hospital links inherited mutations in the BRCA2 gene with an increased risk of developing non-Hodgkin lymphoma in children and adolescents.

25 Jul 2019

Novel therapeutic strategy for treating Lafora Disease shows promise in preclinical study

A team of scientists have designed and tested in mice a novel and promising therapeutic strategy for treating Lafora Disease, a fatal form of childhood epilepsy.

25 Jul 2019

New study reveals the world's top genomic rearrangement detection tools

Published in Nature Communications, the study is the largest of its kind and was led by Walter and Eliza Hall Institute computational biologists Professor Tony Papenfuss, Dr Daniel Cameron and Mr Leon Di Stefano.

25 Jul 2019

Sequencing data could be used to prevent lyme disease

Researchers have successfully sequenced the genome of the animal that could carry the bacteria causing Lyme disease.

25 Jul 2019

Study identifies new mechanism that impacts HIV infection

A team of scientists led by Texas Biomed's Assistant Professor Smita Kulkarni, Ph.D. and Mary Carrington, Ph.D., at the Frederick National Laboratory for Cancer Research, published results of a study that pinpointed a long noncoding RNA molecule which influences a key receptor involved in HIV infection and progression of the disease.

25 Jul 2019

Family experiences of African Americans influence risk and management of Type 2 diabetes

African American families not only share a higher risk for Type 2 diabetes, but many myths and misconceptions about the disease are often passed on from one generation to the next.

25 Jul 2019

Researchers decode factors that contribute to risk of developing motor neuron disease

Trinity College Dublin researchers have found that one in 347 men and one in 436 women can be expected to develop motor neuron disease during their lifetime.

25 Jul 2019

Researchers turn to single-cell analysis to understand a pediatric brain tumor

Investigators at St. Jude Children's Research Hospital and Massachusetts General Hospital, alongside others, have revealed the cells of origin for specific subtypes of medulloblastoma, the most common malignant pediatric brain tumor.

25 Jul 2019

Fat cells may be egging on melanoma cells to become more aggressive

A new study has shown that fat cells could be implicated in the transformation of the melanoma cells in the skin into highly malignant cells that spread to the different organs of the body. A team from the Tel Aviv University, led by Prof. Carmit Levy and Dr. Tamar Golan of the Department of Human Genetics and Biochemistry at TAU's Sackler School of Medicine published their findings in the journal Science Signaling this week.

24 Jul 2019

Measuring pupil dilation and heart rate using AI could enable earlier diagnosis of autism

Autism and other neurodevelopmental disorders often aren't diagnosed until a child is a few years of age, when behavioral interventions and speech/occupational therapy become less effective.

24 Jul 2019

Researchers explore stem cells for answers to how fragile X syndrome develops

The lab of Yongchao Ma, PhD, from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago, discovered how the genetic defect in fragile X syndrome – a type of autism – delays production of neurons (nerve cells) at a critical time in the embryo's brain development.

24 Jul 2019

Extracellular vesical microRNAs from fat cells can disrupt disposal of cholesterol

A multi-institutional team led by research faculty at Children's National in Washington, D.C., finds that extracellular vesicles (EVs) derived from kids' fat can play a pivotal role in ratcheting up risk for atherosclerotic cardiovascular disease well before any worrisome symptoms become visible.

24 Jul 2019

Using wavelength-encoded laser particles to tag tumor cells

A new study, "Wavelength-encoded laser particles for massively multiplexed cell tagging," by scientists in the Wellman Center for Photomedicine has been published in Nature Photonics.

24 Jul 2019