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Scientists find that lipocalin 2 protein disables macrophages in bacterial pneumonia

Macrophages, also known as scavenger cells, play an important role in defending against bacteria and pathogens by activating inflammatory processes. In cases of lung inflammation (pneumonia) caused by pneumococcal bacteria, this important immune response function is hampered and blocked by the protein lipocalin 2.

22 Jul 2013

Implications for treating some common food allergies

Food is an integral part of life; but, for some, it can be harmful. Allergic inflammation caused by inappropriate immune responses to some types of food has become a major public health issue. Over the past ten years, the prevalence of food allergies has increased by nearly 20 percent, affecting an estimated six million people in the U.S.

22 Jul 2013

Vegetation may not protect people from ozone pollution, says new research

During heat waves - when ozone production rises - plants' ozone absorption is curtailed, leaving more pollution in the air, and costing an estimated 460 lives in the UK in the hot summer of 2006.

20 Jul 2013

Researchers discover new functions for PTPN22 gene linked with autoimmune disease

Researchers at the University of Minnesota have identified infection-fighting and inflammation-suppressing functions for a gene associated with human autoimmune disease.

20 Jul 2013

New research uncovers biological ties between obesity and asthma

Genes linked to chronic inflammation in asthma may be more active in people who are obese, according to new research that uncovers several biological ties between obesity and asthma.

19 Jul 2013

NCI awards $1.5M grant to LSUHSC researcher to study role of chronic inflammation in cancer

Yan Cui, PhD, Associate Professor of Microbiology, Immunology, & Parasitology at LSU Health Sciences Center New Orleans and the LSUHSC Stanley S. Scott Cancer Center, has been awarded a $1.5 million grant over five years by the National Cancer Institute to study the role of chronic inflammation in the development and progression of cancer.

19 Jul 2013

New data identifies specific cellular pathways by which RNS60 impacts Alzheimer's Disease

On Wednesday Revalesio Corporation presented new data at the Alzheimer's Association International Conference that identifies the specific cellular pathways by which Revalesio's lead investigational product, RNS60, impacts Alzheimer's Disease. This research, conducted in partnership with Rush University Medical Center, investigates a new category of therapeutics using Revalesio's novel nanotechnology platform.

19 Jul 2013

Idera Pharmaceuticals receives patent related to IMO-8400

Idera Pharmaceuticals, Inc. today announced that the United States Patent and Trademark Office has issued to Idera patent number 8,486,908, providing both composition of matter and method of use protection for IMO-8400.

19 Jul 2013

FDA approves Janssen Biotech's SIMPONI ARIATM for infusion for active rheumatoid arthritis

Janssen Biotech, Inc. announced today the U.S. Food and Drug Administration approval of SIMPONI ARIATM (golimumab) for infusion for the treatment of adults with moderately to severely active rheumatoid arthritis in combination with methotrexate.

19 Jul 2013

Creating, promoting foods containing angiogenesis is the new frontier in dietary health

Creating and promoting foods that contain natural inhibitors of unhealthy angiogenesis - the formation of blood vessels that feed and promote disease, obesity and inflammation - is the "new frontier in dietary health," according to a presentation at the 2013 Institute of Food Technologists Annual Meeting & Food Expo- in Chicago.

18 Jul 2013

Virginia Commonwealth University receives $1.8M grant to study biology of allergic disease

The National Institutes of Health has awarded Virginia Commonwealth University a grant totaling $1.8 million to study the biology of allergic disease - work which may one day point researchers to the development of therapies to fight asthma, allergy and inflammatory conditions such as rheumatoid arthritis, multiple sclerosis and heart disease.

18 Jul 2013

Researchers discover new protein that encourages ‘bad’ blood vessel growth

The discovery of a protein that encourages blood vessel growth, and especially 'bad' blood vessels - the kind that characterise diseases as diverse as cancer, age-related macular degeneration and rheumatoid arthritis - has been reported in the journal Nature.

18 Jul 2013

Health benefits of short-chain fructooliogosaccharides

A new presentation today at the 2013 Institute of Food Technologists (IFT) Annual Meeting & Expo in Chicago- focused on the health benefits of short-chain fructooliogosaccharides (scFOS), which are low-calorie, non-digestible carbohydrates that can improve food taste and texture while aiding immunity, bone health and the growth and balance of important bacteria in the digestive track.

17 Jul 2013

Study shows environmental conditions have stronger influence on human microbiome

Environmental conditions have a much stronger influence on the mix of microbes living in various parts of your body than does competition between species. Instead of excluding each other, microbes that fiercely compete for similar resources are more likely to cohabit the same individual.

17 Jul 2013

Weill Cornell reports new findings from IVIG Phase 3 trial in Alzheimer's disease at AAIC 2013

Weill Cornell Medical College neurologist Dr. Norman Relkin reported new findings today from the Phase 3 clinical trial of IVIG (intravenous immunoglobulin) in mild to moderate Alzheimer's disease at the Alzheimer's Association International Conference in Boston, Mass.

16 Jul 2013

CUMC researchers develop new approach to tailor cancer therapy for individual patient

Columbia University Medical Center (CUMC) researchers are developing a new approach to cancer clinical trials, in which therapies are designed and tested one patient at a time.

16 Jul 2013

Specific types of intestinal bacteria are major contributors to lymphoma

Researchers from UCLA's Jonsson Comprehensive Cancer Center (JCCC) have discovered that specific types of bacteria that live in the gut are major contributors to lymphoma, a cancer of the white blood cells that are part of the human immune system.

16 Jul 2013

FDA approves Gilotrif for patients with late stage non-small cell lung cancer

Companion test also approved to identify appropriate patients The U.S. Food and Drug Administration today approved Gilotrif (afatinib) for patients with late stage (metastatic) non-small cell lung cancer (NSCLC) whose tumors express specific types of epidermal growth factor receptor (EGFR) gene mutations, as detected by an FDA-approved test. Lung cancer is the leading cause of cancer-related death among men and women.

16 Jul 2013

Study: Prosthetic valve endocarditis associated with high one-year mortality rate

Prosthetic valve endocarditis (inflammation and infection involving the heart valves and lining of the heart chambers) remains associated with a high one-year mortality rate and early valve replacement does not appear to be associated with lower mortality compared with medical therapy according to a study by Tahaniyat Lalani, M.D., M.H.S., of the Naval Medical Center, Portsmouth, Virginia, and colleagues.

16 Jul 2013

TSRI scientists design drug candidate that increases exercise endurance in animal models

An international group of scientists has shown that a drug candidate designed by scientists from the Florida campus of The Scripps Research Institute (TSRI) significantly increases exercise endurance in animal models.

15 Jul 2013

Inflammation News and Research

Scientists find that lipocalin 2 protein disables macrophages in bacterial pneumonia

Implications for treating some common food allergies

Vegetation may not protect people from ozone pollution, says new research

Researchers discover new functions for PTPN22 gene linked with autoimmune disease

New research uncovers biological ties between obesity and asthma

NCI awards $1.5M grant to LSUHSC researcher to study role of chronic inflammation in cancer

New data identifies specific cellular pathways by which RNS60 impacts Alzheimer's Disease

Idera Pharmaceuticals receives patent related to IMO-8400

FDA approves Janssen Biotech's SIMPONI ARIATM for infusion for active rheumatoid arthritis

Creating, promoting foods containing angiogenesis is the new frontier in dietary health

Virginia Commonwealth University receives $1.8M grant to study biology of allergic disease

Researchers discover new protein that encourages ‘bad’ blood vessel growth

Health benefits of short-chain fructooliogosaccharides

Study shows environmental conditions have stronger influence on human microbiome

Weill Cornell reports new findings from IVIG Phase 3 trial in Alzheimer's disease at AAIC 2013

CUMC researchers develop new approach to tailor cancer therapy for individual patient

Specific types of intestinal bacteria are major contributors to lymphoma

FDA approves Gilotrif for patients with late stage non-small cell lung cancer

Study: Prosthetic valve endocarditis associated with high one-year mortality rate

TSRI scientists design drug candidate that increases exercise endurance in animal models

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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