Immunoglobulin News and Research

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A highly sensitive and specific antibody test for COVID-19

A new proof-of-concept study by UK researchers, currently available on the medRxiv* preprint server, describes the development of an enzyme-linked immunosorbent assay that can be used when lower levels of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) specific-antibodies are present in serum and saliva samples.

21 Jun 2020

C-Path's Transplant Therapeutics Consortium receives positive FDA response for its Letter of Intent

Critical Path Institute announced today that its Transplant Therapeutics Consortium has received a positive response to its Letter of Intent from the U.S. Food and Drug Administration detailing the decision to accept the Composite Biomarker Panel (iBox Scoring System) into the Center for Drug Evaluation and Research (CDER) Biomarker Qualification Program.

17 Jun 2020

Testing reveals 11 percent of people in Geneva infected with SARS-CoV-2

Now, a team of researchers at Geneva University Hospitals has found that less than 11 percent of the population in Geneva has contracted the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Their research is published in the journal The Lancet.

15 Jun 2020

Study: Only a minority of Geneva population has been infected by Covid-19 pandemic

A study carried out among 2'766 people by the University Hospitals of Geneva (HUG), the Geneva Centre for Emerging Viral Diseases, and the University of Geneva (UNIGE), Switzerland, reveals that, at the time of the decline of the Coronavirus pandemic, only 10.8% of the Geneva population had been infected with Covid-19.

12 Jun 2020

Turning autoimmunity drugs into anti-cancer treatments

Professor Mark Cragg speaks to News-Medical about his research which involves turning autoimmunity drugs into anti-cancer treatments.

11 Jun 2020

Maternal SARS-CoV-2 infection not harmful in first trimester pregnancies

A new Danish study published on the preprint server medRxiv in June 2020 shows that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in early pregnancy does not carry an increased risk of fetal harm.

10 Jun 2020

Females mount stronger T-cell response to SARS-CoV-2

A new study published on the preprint server medRxiv in June 2020 shows that immune cells, antibody levels, cytokine levels, and viral loads contribute to the sex difference seen in response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

10 Jun 2020

Seroprevalence of IgM and IgG against SARS-CoV-2 in China

A new study published in the journal Nature Medicine in June 2020 reports the seroprevalence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) across China. This may help to understand the actual prevalence of the virus in the current pandemic.

10 Jun 2020

SARS-CoV-2 invasion of central nervous system through olfactory tract

As the COVID-19 pandemic continues to claim lives throughout the world, the evidence is mounting that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the respiratory tract as well as the central nervous system. Now, a new study by German researchers published on the preprint server bioRxiv in June 2020 describes various neurological manifestations of COVID-19, as well as the underlying pathophysiology.

7 Jun 2020

Trial results show efficacy of netakimab for treating moderate-to-severe plaque psoriasis

Netakimab is a humanized anti-interleukin 17A antibody approved for the treatment of moderate-to-severe plaque psoriasis.

5 Jun 2020

Octapharma extends support for COVID-19 study following promising preliminary data

Following positive preliminary data, Octapharma USA is extending funding for an investigator-initiated study (IIS) focused on treating the most critical patients at the heart of the coronavirus pandemic, those experiencing hypoxia and who are at the highest risk of requiring mechanical ventilation.

3 Jun 2020

Siemens receives FDA approval for SARS-CoV-2 antibody test

Siemens Healthineers has announced that the U.S. Food and Drug Administration (FDA) had issued an Emergency Use Authorization for its total antibody test to detect the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies, including Immunoglobulin M (IgM) and Immunoglobulin G (IgG) in the blood.

3 Jun 2020

Measuring the binding of SARS-CoV-2 antibodies to the COVID spike protein using SPR

Ryan Denomme, the CEO of Nicoya, speaks to News-Medical on their SARS-CoV-2 research using their SPR technology.

From Nicoya Lifesciences 28 May 2020

IgG antibodies reduce viral load of SARS-CoV-2

A study conducted by researchers at the University of Washington has highlighted the importance of serological testing for infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

26 May 2020

New technique for fast, easy optimization of antibodies using chicken cells

Antibodies for potential use as medicines can be made rapidly in chicken cells grown in laboratories. Researchers refer to their technique as the human ADLib system, short for autonomously diversifying libraries.

26 May 2020

Prediction of incubation period for COVID-19 and other viruses

A new study published on the preprint server bioRxiv* in May 2020 provides a method to estimate the incubation period for any new pathogen, which could help to define the optimal quarantine period necessary to keep the spread of the causative agent in check.

22 May 2020

Producing virus-specific antibodies after COVID-19

In order to design effective vaccines for COVID-19, we need to understand our immune responses. News-Medical speaks to Professor Chen Dong to find out more.

21 May 2020

FDA approves IND application by Octapharma USA for severe COVID-19 patients

The U.S. Food and Drug Administration (FDA) has approved the investigational new drug (IND) application submitted by Octapharma USA for a phase three clinical trial on the efficacy and safety of Octagam 10% [Immune Globulin Intravenous (Human)] therapy in COVID-19 patients with severe disease progression.

20 May 2020

New and unexplored angle in the binding of SARS-CoV-2 to host cells

Researchers in the Netherlands, Cuba, and Italy have made important discoveries about the carbohydrate-mediated binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein to host cell lectin receptors and host lung microbiota.

17 May 2020

New algorithm could help investigate the genetic clues behind immunity

Scientists with UC San Diego's Jacobs School of Engineering and the Qualcomm Institute have developed a new gene prediction algorithm, called MINING-D, that could help researchers investigate the genetic clues behind the variation of symptoms shown in COVID-19 patients - information that is key to creating a versatile and effective vaccine.

15 May 2020