Kinase News and Research

RSS

Study provides new insight into how brain stem cells are activated

Our brains are notoriously bad at regenerating cells that have been lost through injury or disease. While therapies using neural stem cells (NSCs) hold the promise of replacing lost cells, scientists need to better understand how NSCs behave in the brain in order to develop effective treatments.

7 Jun 2019

Still-to-be-approved drug proves to be new option for treating active rheumatoid arthritis

In a large-scale, international study led by renowned rheumatologist Josef Smolen from the Department of Medicine III, a still-to-be-approved drug containing the selective janus kinase inhibitor upadacitinib has proved itself to be a new option for treating active rheumatoid arthritis.

7 Jun 2019

Study searches for the origins of depressive symptoms in Huntington's disease

About 40% of the affected patients with Huntington's disease -a neurodegenerative pathology- show depression symptoms, even in early stages before the apparition of the typical motor symptoms of the disease.

31 May 2019

Study sheds light on design of pharmacological strategies to treat depression in Huntington's disease

About 40 % of the affected patients with Huntington's disease -a neurodegenerative pathology- show depression symptoms, even in early stages before the apparition of the typical motor symptoms of the disease.

31 May 2019

Researchers discover COMMD3/8 protein complex as molecule involved in immune cell migration

A team of researchers led by Kazuhiro Suzuki from the Immunology Frontier Research Center at Osaka University discovered the COMMD3/8 complex as a molecule involved in immune cell migration, clarifying that the complex plays a critical role in the establishment of immune responses.

31 May 2019

UC Santa Cruz researchers determine structure of a 'master switch' for cell division

Unregulated cell division is a hallmark of cancer, and one of the key proteins involved in controlling cell division is called FoxM1.

29 May 2019

Characterizing potential therapeutic target to increase heart function after heart attack

A University of Houston College of Pharmacy researcher is characterizing a potential therapeutic target to increase heart function following a heart attack, helping alleviate the symptoms of heart failure.

23 May 2019

Researchers identify enzymes that protect people from diabetic kidney disease

A new study from Joslin Diabetes Center has proven that certain biological protective factors play a large role in preventing diabetic kidney disease in certain people. The study was published today in Diabetes Care.

21 May 2019

Researchers discover biochemical agent responsible for blood pressure drop in sepsis

A study conducted by an international group of researchers has overturned the understanding of life-threatening inflammatory diseases such as sepsis, pointing to a biochemical agent that may be involved in the rapid decline in blood pressure that occurs in the advanced stage of sepsis and usually causes the patient's death. This discovery could pave the way for novel therapeutic approaches.

14 May 2019

Study provides first evidence of crosstalk between the heart and fat cells

Like sending a letter through the mail or a text over a cellular network, the heart can generate messages that travel long distances through the body.

10 May 2019

Scientists unravel mechanism of action of antitumor drug used to treat glioblastoma

Glioblastoma is an incurable type of brain tumor that is frequently associated with mutations in the epidermal growth factor receptor.

3 May 2019

Study finds promising new treatment for infants with Noonan Syndrome

Noonan Syndrome is a rare genetic syndrome typically evident at birth and often linked to early-onset severe heart disease.

30 Apr 2019

CircRNAs bind to dsRNA-activated protein kinase which is linked to innate immunity

Covalently closed circular RNAs are produced by precursor mRNA back-splicing the exons of thousands of genes in eukaryotes.

26 Apr 2019

Scientists use NIR light and injected DNA nanodevice to guide stem cells to injury

What if doctors had a remote control that they could use to steer a patient's own cells to a wound to speed up the healing process?

18 Apr 2019

Innate immune sensor responding to gut microbes can suppress liver cancer

UT Southwestern researchers have found that a protein in the body's innate immune system that responds to gut microbes can suppress the most common type of liver cancer.

17 Apr 2019

Removing damaged mitochondria may relieve chronic inflammatory conditions

Researchers have discovered a potential new way to treat chronic inflammatory diseases, by eliminating damaged mitochondria before they trigger excessive inflammation.

12 Apr 2019

Researchers discover unique approach to treat some chronic inflammatory diseases

Inflammation is a balanced physiological response -- the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and chronic diseases.

12 Apr 2019

Combined inhibition of EGFR and c-RAF kinase shows regression of most aggressive pancreatic cancer

Researchers from the Experimental Oncology Group, led by Mariano Barbacid at the Spanish National Cancer Research Centre, have published in Cancer Cell the results of a study that shows full regression of advanced pancreatic ductal adenocarcinoma upon combined inhibition of the epidermal growth factor receptor and c-RAF kinase.

12 Apr 2019

Reduced ADK expression can make liver more susceptible to carcinogenic damage

A new study has shown that reduced adenosine kinase expression in the liver can make it more susceptible to carcinogenic damage and the development of liver cancer.

11 Apr 2019

New molecule could help fight type 2 diabetes and non-alcoholic fatty liver disease

A new molecule -EPB-53-, could help fight type 2 diabetes and the non-alcoholic fatty liver disease, according to a new study led by the team of Manuel Vázquez-Carrera, from the Faculty of Pharmacy and Food Sciences and the Institute of Biomedicine of the University of Barcelona, and the Diabetes and Associated Metabolic Diseases Networking Biomedical Research Center.

10 Apr 2019

Kinase News and Research

Study provides new insight into how brain stem cells are activated

Still-to-be-approved drug proves to be new option for treating active rheumatoid arthritis

Study searches for the origins of depressive symptoms in Huntington's disease

Study sheds light on design of pharmacological strategies to treat depression in Huntington's disease

Researchers discover COMMD3/8 protein complex as molecule involved in immune cell migration

UC Santa Cruz researchers determine structure of a 'master switch' for cell division

Characterizing potential therapeutic target to increase heart function after heart attack

Researchers identify enzymes that protect people from diabetic kidney disease

Researchers discover biochemical agent responsible for blood pressure drop in sepsis

Study provides first evidence of crosstalk between the heart and fat cells

Scientists unravel mechanism of action of antitumor drug used to treat glioblastoma

Study finds promising new treatment for infants with Noonan Syndrome

CircRNAs bind to dsRNA-activated protein kinase which is linked to innate immunity

Scientists use NIR light and injected DNA nanodevice to guide stem cells to injury

Innate immune sensor responding to gut microbes can suppress liver cancer

Removing damaged mitochondria may relieve chronic inflammatory conditions

Researchers discover unique approach to treat some chronic inflammatory diseases

Combined inhibition of EGFR and c-RAF kinase shows regression of most aggressive pancreatic cancer

Reduced ADK expression can make liver more susceptible to carcinogenic damage

New molecule could help fight type 2 diabetes and non-alcoholic fatty liver disease

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

Latest News