Pancreas News and Research

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The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as an exocrine gland, secreting pancreatic juice containing digestive enzymes that pass to the small intestine. These enzymes help in the further breakdown of the carbohydrates, protein, and fat in the chyme.

Next-generation sequencing assay shows accuracy, sensitivity in detecting genetic mutations in tumors

One of the most promising areas of cancer research is personalized therapy using precision medicine. The National Cancer Institute's NCI-MATCH is a large, ongoing clinical trial that matches tumors to therapies based on the tumor's genetic characteristics.

7 Feb 2017

Scientists develop unique method to fix genes in living organisms

A unique gene-editing method that efficiently inserts DNA into genes located in dividing and non-dividing cells of living rats has been developed by a team of international researchers, including scientists from KAUST.

31 Jan 2017

Onset of diabetes or rapidly deteriorating condition could be first sign of hidden pancreatic cancer

Patients and their doctors should be aware that the onset of diabetes, or a rapid deterioration in existing diabetes that requires more aggressive treatment, could be a sign of early, hidden pancreatic cancer, according to research presented at the European Cancer Congress 2017 today.

30 Jan 2017

Johns Hopkins scientists reveal extra centrosomes can promote tumor formation in mice

When a cell is dividing, two identical structures, called centrosomes, move to opposite sides of the cell to help separate its chromosomes into the new cells.

28 Jan 2017

Increased levels of physical activity linked to decreased insulin resistance, inflammation biomarkers

A new report, based on data from the Framingham Heart Study (FHS), suggests that insulin resistance, a predictor of cardiovascular risk and the development of diabetes, may be modulated with even modest levels of physical activity.

27 Jan 2017

Human cells integrated into pig and cow embryos

Scientists have shown for the first time that undifferentiated human stem cells can be integrated into early embryos of both pigs and cattle. The construction of such interspecies embryos may represent an important development in the generation of organs for transplant.

27 Jan 2017

Islets from rat-grown mouse pancreases can help reverse disease in diabetic mice

Mouse pancreases grown in rats generate functional, insulin-producing cells that can reverse diabetes when transplanted into mice with the disease, according to researchers at the Stanford University School of Medicine and the Institute of Medical Science at the University of Tokyo.

25 Jan 2017

HCI scientists uncover new way that bones get destroyed through breast cancer

Once breast cancer spreads through the body, it can degrade a patient's healthy bones, causing numerous problems. Scientists at Huntsman Cancer Institute at the University of Utah have identified a new way that bones get destroyed through cancer.

25 Jan 2017

Scientists develop new method to accurately determine gene expression in single cells

At Baylor College of Medicine, scientists have developed a method that allows them to accurately determine the genes expressed in single cells.

25 Jan 2017

Type 1 diabetes patients show distinct signs of gut inflammation, study reveals

People with Type 1 diabetes exhibit inflammation in the digestive tract and gut bacteria¬—a pattern that differs from individuals who do not have diabetes or those who have celiac disease, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

20 Jan 2017

Exposure to insecticides that mimic melatonin could put people at higher risk for diabetes

Synthetic chemicals commonly found in insecticides and garden products bind to the receptors that govern our biological clocks, University at Buffalo researchers have found.

19 Jan 2017

Researchers uncover how stress hormone prevents digestive enzymes from damaging pancreas

UT Southwestern Medical Center researchers have uncovered the mechanism by which the stress hormone FGF21 keeps digestive enzymes from damaging the pancreas.

18 Jan 2017

Protein involved in pancreatic cancer development plays more complicated role, study finds

A protein thought to fuel pancreatic cancer development plays a much more complicated role, a new study finds.

18 Jan 2017

Epigenetic changes drive successful metastases of pancreatic cancer cells

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.

17 Jan 2017

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Metastatic pancreatic cancer -- cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths -- changes its metabolism and is "reprogrammed" for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics.

16 Jan 2017

Epigenetic changes favor development of fatty liver in humans and mice

Mice with a strong tendency to obesity already exhibit epigenetic changes at six weeks of age, inducing the liver to amplify its production of the enzyme DPP4 and release it into the circulation. Over the long term, this favors the development of a fatty liver.

9 Jan 2017

Pancreas News and Research

Further Reading

Next-generation sequencing assay shows accuracy, sensitivity in detecting genetic mutations in tumors

Scientists develop unique method to fix genes in living organisms

Onset of diabetes or rapidly deteriorating condition could be first sign of hidden pancreatic cancer

Johns Hopkins scientists reveal extra centrosomes can promote tumor formation in mice

Increased levels of physical activity linked to decreased insulin resistance, inflammation biomarkers

Human cells integrated into pig and cow embryos

Islets from rat-grown mouse pancreases can help reverse disease in diabetic mice

HCI scientists uncover new way that bones get destroyed through breast cancer

Scientists develop new method to accurately determine gene expression in single cells

Type 1 diabetes patients show distinct signs of gut inflammation, study reveals

Exposure to insecticides that mimic melatonin could put people at higher risk for diabetes

Researchers uncover how stress hormone prevents digestive enzymes from damaging pancreas

Protein involved in pancreatic cancer development plays more complicated role, study finds

Epigenetic changes drive successful metastases of pancreatic cancer cells

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Epigenetic changes favor development of fatty liver in humans and mice

Regular aspirin use lowers pancreatic cancer risk by 50%, new study finds

Scientists use pluripotent stem cells to generate human stomach tissues in laboratory

Chemical modification improves release and availability of insulin, research shows

200th live donor kidney transplant offers promise of new life for the New Year

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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