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Analyzing biophysical restrictions of SARS-CoV-2 N-terminal domain

Analyzing biophysical restrictions of SARS-CoV-2 N-terminal domain

In a recent article posted to the bioRxiv* preprint server, researchers at the University of Illinois at Urbana-Champaign, Scripps Research Institute, and Case Western Reserve University evaluated the biophysical limitations of the spike (S) N-terminal domain (NTD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

23 Jun 2022

SARS-CoV-2 evades natural killer cell cytotoxic responses

SARS-CoV-2 evades natural killer cell cytotoxic responses

In a recent study posted to the bioRxiv* preprint server, researchers at Stanford University School of Medicine revealed the mechanism via severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) escapes natural killer (NK) cell cytotoxic reactions.

22 Jun 2022

Study provides better understanding of the brain pathways that control nausea

Study provides better understanding of the brain pathways that control nausea

Nausea is a bit of a catchall sensation for the human body: the unpleasant sick feeling can hit us as a result of everything from pregnancy or a migraine to eating spoiled food or undergoing chemotherapy.

22 Jun 2022

Immune and central nervous systems may play a key role in ALS, Mount Sinai researchers report

Immune and central nervous systems may play a key role in ALS, Mount Sinai researchers report

The immune system may play a fundamental role along with the central nervous system in amyotrophic lateral sclerosis (ALS), also known as "Lou Gehrig's disease," Mount Sinai researchers report.

22 Jun 2022

Researchers identify biomarkers that could be targets for novel drugs to treat glioblastoma

Researchers identify biomarkers that could be targets for novel drugs to treat glioblastoma

Biomarkers that could be targets for novel drugs to treat glioblastoma brain tumors have been identified by investigators at Georgetown Lombardi Comprehensive Cancer Center, providing hope for a cancer that is highly lethal.

22 Jun 2022

Novel drug molecule targets T-cells causing inflammation in heart failure patients

Novel drug molecule targets T-cells causing inflammation in heart failure patients

Researchers at The Ohio State University Wexner Medical Center and College of Medicine have developed a novel drug molecule that targets T-cells causing inflammation in heart failure patients, stopping further progression of the disease.

22 Jun 2022

Disrupting tuft cell development may be a new way to treat deadly lung cancer

Disrupting tuft cell development may be a new way to treat deadly lung cancer

Cold Spring Harbor Laboratory Professor Christopher Vakoc's team discovered in 2018 a new type of small-cell lung cancer. The cancer originates from cells known as tuft cells.

22 Jun 2022

Preclinical study unlocks the promise of CAR T-cell therapy for treatment of solid tumors

Preclinical study unlocks the promise of CAR T-cell therapy for treatment of solid tumors

Scientists at St. Jude Children's Research Hospital identified a molecular mechanism that in a preclinical study unlocked the promise of CAR T–cell therapy for treatment of solid tumors.

22 Jun 2022

INTEGRA’s PIPETBOY acu 2 pipette controller takes a deep dive into cellular physics

INTEGRA’s PIPETBOY acu 2 pipette controller takes a deep dive into cellular physics

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From INTEGRA Biosciences 22 Jun 2022

The role of smartphone apps during the COVID-19 pandemic

The role of smartphone apps during the COVID-19 pandemic

In a recent study published in Nature Biotechnology, researchers assessed the role of smartphone apps during the coronavirus disease 2019 (COVID-19) pandemic.

22 Jun 2022

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

In a recent review published in Immunity, researchers explored potential mechanisms of neuro-immune pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

22 Jun 2022

Gene expression regulation by N6-methyladenosine

Gene expression regulation by N6-methyladenosine

A recent study published in Molecular Cell reviewed the control of gene expression by N6-methyladenosine (m6A), a modified nucleotide in the messenger ribonucleic acid (mRNA).

22 Jun 2022

Deaths due to fungal infections during the COVID-19 pandemic in the US

Deaths due to fungal infections during the COVID-19 pandemic in the US

A recent study published in Clinical Infectious Diseases assessed deaths due to fungal infections during the coronavirus disease 2019 (COVID-19) pandemic in the United States (US).

22 Jun 2022

Even asymptomatic maternal COVID-19 can potentially cause pregnancy complications

Even asymptomatic maternal COVID-19 can potentially cause pregnancy complications

A recent study published in the Cell Reports journal analyzed immune ecology at the placenta in mild or asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy.

22 Jun 2022

Specific retinal cell appears to be good at housing Ebola and other viruses

Specific retinal cell appears to be good at housing Ebola and other viruses

A specific cell within our retina, the light-sensitive part of our eyes responsible for sending visual information to our brain, appears to be particularly good at housing Ebola and other viruses, new research has found.

22 Jun 2022

Study shows molecular details of HIV-1 assembly and viral envelope protein incorporation

Study shows molecular details of HIV-1 assembly and viral envelope protein incorporation

Assembly of HIV-1, which causes AIDS, takes place on the inner plasma membrane leaflet of infected cells, a geometric building process that creates hexamers out of trimers of the viral Gag protein, as guided by Gag's N-terminal matrix domain.

21 Jun 2022

Scientists discover 15 additional genetic mutations linked to KCNK9 imprinting syndrome

Scientists discover 15 additional genetic mutations linked to KCNK9 imprinting syndrome

A collaborative team of scientists led by Mayo Clinic's Center for Individualized Medicine has discovered 15 additional genetic mutations in the KCNK9 gene that cause a neurodevelopmental syndrome.

21 Jun 2022

Gelatin in Pacific whiting skin may help prevent wrinkles caused by ultraviolet radiation

Gelatin in Pacific whiting skin may help prevent wrinkles caused by ultraviolet radiation

The gelatin in the skin of Pacific whiting, an abundant fish on the Pacific Coast of North America, may help prevent skin wrinkling caused by ultraviolet radiation, a new Oregon State University study found.

21 Jun 2022

Researchers investigate the cell adhesion behavior on spider silk for medical use

Researchers investigate the cell adhesion behavior on spider silk for medical use

Silk has been cultivated for centuries by domesticated silkworms, but it has been difficult to commercially produce spider silk in bulk due to their cannibalistic tendencies.

21 Jun 2022

Erectile dysfunction drugs may be able to boost the effect of chemotherapy in esophageal cancer

Erectile dysfunction drugs may be able to boost the effect of chemotherapy in esophageal cancer

A group of drugs commonly used to treat erectile dysfunction may be able to boost the effect of chemotherapy in esophageal cancer, according to new research funded by Cancer Research UK and the Medical Research Council.

21 Jun 2022

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