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New signaling systems discovered in human cells

The human cell has a wide variety of receptors on its surface that many molecules and therapeutic drugs can bind to in order to activate signals inside the cell to regulate different physiological functions. GPCRs are the largest - and a very important - family of receptors on human cells.

31 Oct 2019

OHSU receives $2.1 million to develop new vaccine additives for tropical viruses

Sometimes vaccines need a little help to protect people against infectious diseases.

31 Oct 2019

Researchers identify new kidney cancer subtypes and clues to better diagnosis, treatment

In what is believed to be the most comprehensive molecular characterization to date of the most common - and often treatment-resistant - form of kidney cancer, researchers at Johns Hopkins' departments of pathology and oncology, Johns Hopkins Kimmel Cancer Center, and the Johns Hopkins University School of Medicine report evidence for at least three distinct subtypes of clear cell renal cell carcinoma (ccRCC), along with new revelations about the proteins that define them.

From Johns Hopkins Medicine 31 Oct 2019

Researchers discover key mechanism in insulin release by cholesterol metabolite

Insulin which is released by pancreatic beta-cells is the main regulator of blood sugar. Previous and current studies by a research group at Lund University in Sweden have identified around hundred different receptors on the surface of the beta-cells, with a diverse functional impact on the beta-cells.

31 Oct 2019

Discovery has potential to put the brakes on Parkinson's 'runaway train'

Researchers at the University of Dundee have made a discovery they believe has the potential to put the brakes on the 'runaway train' that is Parkinson's disease.

31 Oct 2019

Optometrists reduce opioid prescription without increasing pain

Optometrists at the University of Michigan have introduced a new approach to prescribing opioids in an effort to help curb the nation’s opioid epidemic.

31 Oct 2019

New deep learning tool will advance personalized medicine for musculoskeletal diseases

Personalized medicine has stirred the imagination of drugs and therapies that are individually tailored to patients.

31 Oct 2019

Researchers describe how malaria parasites prepare blueprint to attack humans

Within seconds after an infected mosquito bites, the malaria parasite navigates the host skin and blood vessels to invade the liver, where it will stay embedded until thousands of infected cells burst into the bloodstream, launching malaria's deadly blood-stage infection.

31 Oct 2019

Robotic-assisted surgery can improve longevity of knee replacement

Forty-nine-year-old James Benfante's knee pain got so bad he dreaded walking from the train station to his job or even standing in line.

31 Oct 2019

Mechanism for antibiotic resistance in Pseudomonas explained in new research

A new study has revealed the underlying mechanism of development of antibiotic resistance among Pseudomonas aeruginosa (P. aeruginosa). Pseudomonas is known to cause severe and often life threatening infections in humans. These infections become further difficult to treat because of the development of resistance against commonly used antibiotics.

30 Oct 2019

Drug delivery still has great development potential

Nanocapsules and other containers can transport drugs through a patient's body directly to the origin of the disease and release them there in a controlled manner. Such sophisticated systems are occasionally used in cancer therapy. Because they work very specifically, they have fewer side effects than drugs that are distributed throughout the entire organism.

30 Oct 2019

Researchers develop new therapeutic concept for treatment of temporal lobe epilepsy

Teams of researchers from Charité - Universitätsmedizin Berlin and the Medical University of Innsbruck have developed a new therapeutic concept for the treatment of temporal lobe epilepsy.

30 Oct 2019

New way to slow and reverse fibrosis identified

In cell and mouse models, Mayo Clinic researchers and collaborators have identified a way to slow and reverse the process of uncontrolled internal scarring, called fibrosis.

30 Oct 2019

Study finds declining trend in prevalence of cannabis use disorder among frequent users

The prevalence of cannabis use disorder decreased in 2002 to 2016 among frequent users, according to a new study conducted at Columbia University Mailman School of Public Health.

30 Oct 2019

UVA research sheds light on why infant seizures have lifelong effects

A doctor at University of Virginia Children's is using an elegant new approach to mapping brain activity to shed light on what happens during seizures in newborns that can lead to behavioral issues and learning disabilities much later.

30 Oct 2019

New study finds racial/ethnic variation in discharge destination after knee replacement surgery

A large study analyzing 107,000 knee replacement surgeries found that African Americans were significantly more likely than white patients to be discharged to an inpatient rehabilitation or skilled nursing facility rather than home care after the procedure. Researchers also found that African American patients under 65 were more likely to be readmitted to the hospital within 90 days of a knee replacement.

30 Oct 2019

Rilpivirine drug used for HIV treatment also suppresses Zika virus infection

Like an adjustable wrench that becomes the "go-to" tool because it is effective and can be used for a variety of purposes, an existing drug that can be adapted to halt the replication of different viruses would greatly expedite the treatment of different infectious diseases.

30 Oct 2019

Drugs News and Research

New signaling systems discovered in human cells

OHSU receives $2.1 million to develop new vaccine additives for tropical viruses

Researchers identify new kidney cancer subtypes and clues to better diagnosis, treatment

Researchers discover key mechanism in insulin release by cholesterol metabolite

Discovery has potential to put the brakes on Parkinson's 'runaway train'

Optometrists reduce opioid prescription without increasing pain

New deep learning tool will advance personalized medicine for musculoskeletal diseases

Researchers describe how malaria parasites prepare blueprint to attack humans

Robotic-assisted surgery can improve longevity of knee replacement

Mechanism for antibiotic resistance in Pseudomonas explained in new research

Drug delivery still has great development potential

Researchers develop new therapeutic concept for treatment of temporal lobe epilepsy

New way to slow and reverse fibrosis identified

Study finds declining trend in prevalence of cannabis use disorder among frequent users

UVA research sheds light on why infant seizures have lifelong effects

New study finds racial/ethnic variation in discharge destination after knee replacement surgery

Rilpivirine drug used for HIV treatment also suppresses Zika virus infection

Syringe-injectable, self-expandable and ultraconformable magnetic nanosheets developed

DGIST and Ahn-Gook Pharmaceutical sign R&D agreement for development of anti-cancer antibody

Newly discovered immune control switch could protect the brains of premature babies

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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