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Review article shows sublingual immunotherapy may be useful for allergic rhinitis, asthma

In an examination of a type of treatment for allergic rhinitis and asthma that is used in Europe but not approved by the U.S. Food and Drug Administration, researchers found moderate strength in the evidence from previous studies to support the use of sublingual immunotherapy for the treatment of these conditions, according to an article in the March 27 issue of JAMA.

27 Mar 2013

Research paper highlights implementation of infectious disease curriculum in Boston Public Schools

A research paper published online this month in Academic Medicine highlights the successful development, implementation, and effects of an infectious disease curriculum that has now been piloted in five Boston Public Schools.

27 Mar 2013

Academic medical centers launch ASD sub-registry within ResearchMatch

Each year, only five percent of the estimated 1.5 million children with an autism spectrum disorder in the US participate in clinical research studies. This is in stark contrast to pediatric cancer studies, which have a nearly 90 percent enrollment rate - a rate that has helped advance treatment and outcomes for childhood cancers substantially in the last decade.

27 Mar 2013

Auxilium Pharmaceuticals reports positive results from phase IIa Frozen Shoulder Syndrome clinical trial

Auxilium Pharmaceuticals, Inc., a specialty biopharmaceutical company, today announced positive data for collagenase clostridium histolyticum or CCH which is being developed for the potential treatment, if approved by the U.S. Food and Drug Administration, of adult patients with adhesive capsulitis, commonly known as Frozen Shoulder syndrome.

26 Mar 2013

Biomedical researcher discovers new technique to measure oxygen in individual red blood cells

In an engineering breakthrough, a Washington University in St. Louis biomedical researcher has discovered a way to use light and color to measure oxygen in individual red blood cells in real time.

26 Mar 2013

Study projects potential impact of FDA-approved anti-obesity medications on Medicare spending

VIVUS, Inc. announced today that a new study demonstrates that effective medical treatment providing 10% to 15% weight loss could lead to significant improvements in Medicare spending by reversing or reducing significant health consequences such as type 2 diabetes, hypertension and dyslipidemia in obese or overweight patients.

25 Mar 2013

Japan's MHLW approves XELJANZ for treatment of adults with rheumatoid arthritis

Pfizer Inc. announced today that the Japanese Ministry of Health, Labor and Welfare has approved XELJANZ (tofacitinib citrate) for the treatment of adults with rheumatoid arthritis who have had an inadequate response to existing therapies.

25 Mar 2013

New guidance highlights risk factors and treatments for osteoporosis in postmenopausal women

A new Guidance recently published by the European Society for Clinical and Economic Aspects of Osteoporosis (ESCEO) and the International Osteoporosis Foundation (IOF) reflects the most current advances in the diagnosis and management of osteoporosis, the 'silent disease' which affects up to one in two postmenopausal women.

25 Mar 2013

Anti-inflammatory drug naproxen may exhibit antiviral activity against influenza A virus

The over-the-counter anti-inflammatory drug naproxen may also exhibit antiviral activity against influenza A virus, according to a team of French scientists. The finding, the result of a structure-based investigation, is published online ahead of print in the journal Antimicrobial Agents and Chemotherapy.

25 Mar 2013

LMU researchers identify microRNA that offers promising target for new therapies

Atherosclerosis, an inflammatory reaction, is at the root of the most common forms of cardiovascular disease. Researchers at Ludwig-Maximilians-Universitaet in Munich have now identified a microRNA that plays a prominent role in the process, and offers a promising target for new therapies.

25 Mar 2013

Study shows physically active healthcare providers more likely to advise patients to lead active lifestyle

Physically active healthcare providers were more likely than their inactive counterparts to advise patients to lead an active lifestyle in a study presented at the American Heart Association's Epidemiology and Prevention/Nutrition, Physical Activity and Metabolism 2013 Scientific Sessions.

25 Mar 2013

Botulism Antitoxin Heptavalent gets FDA approval for patients showing signs of botulism

The U.S. Food and Drug Administration announced today that it has approved Botulism Antitoxin Heptavalent (A, B, C, D, E, F, G)-(Equine) to treat patients showing signs of botulism following documented or suspected exposure to botulinum neurotoxin.

25 Mar 2013

Scientists identify a new way to develop potential drugs for TB

Scientists have developed a way to pinpoint promising drugs to fight tuberculosis (TB) and other diseases without setting foot in the laboratory.

24 Mar 2013

Study of genetically modified immune cells could help improve promising treatment for melanoma

A new study of genetically modified immune cells by scientists from UCLA and the California Institute of Technology could help improve a promising treatment for melanoma, an often fatal form of skin cancer.

24 Mar 2013

Male circumcision a 'staggeringly under-utilized tool'

"PrePex, the new nonsurgical circumcision tool experts believe could revolutionize the prevention of HIV and AIDS in sub-Saharan Africa, is easier to assemble than a toy you might find in a Happy Meal," freelance journalist Patrick Adams writes in the New York Times' "Opinionator" blog.

22 Mar 2013

Effectiveness of candidate malaria vaccine decreases over time, study shows

"The effectiveness of an experimental malaria vaccine developed by GlaxoSmithKline wanes over time, with the shot protecting only 16.8 percent of children over four years, according to trial data," Reuters reports.

22 Mar 2013

Blocked bile ducts can be effectively treated with metal stents

A multi-center analysis, led by Weill Cornell Medical College and published in the Journal of Clinical Gastroenterology, shows the use of temporary "fully covered self-expanding metal stents" (FCSEMS) can effectively fix a painful and potentially life-threatening benign biliary stricture -- a severely blocked or narrowed bile duct.

21 Mar 2013

Positive results from Affinium Pharmaceuticals' Phase 2a clinical trial of AFN-1252 in ABSSSI

Affinium Pharmaceuticals announced today that its Phase 2a clinical trial evaluating oral AFN-1252 in acute bacterial skin & skin structure infections demonstrated excellent efficacy and safety data, marking a significant proof-of-concept milestone for Affinium's first-in-class, novel antibiotic targeted against bacterial fatty acid biosynthesis inhibition (FabI inhibitors).

21 Mar 2013

Researchers complete phase II clinical trial of dasatinib for patients with higher-risk MDS

Researchers at Moffitt Cancer Center have completed a phase II clinical trial to determine the safety and efficacy of dasatinib for patients with higher-risk myelodysplastic syndromes, chronic myelomonocytic leukemia, or acute myeloid leukemia resulting from MDS and have failed treatment with azanucleosides.

21 Mar 2013

New biodegradable nanoparticles deliver inflammation-resolving drugs to sites of tissue injury

A multicenter team of researchers, including scientists at Columbia University Medical Center (CUMC), Brigham and Women's Hospital (BWH), Mount Sinai School of Medicine, and Massachusetts Institute of Technology, has developed biodegradable nanoparticles that are capable of delivering inflammation-resolving drugs to sites of tissue injury.

20 Mar 2013

Efficacy News and Research

Review article shows sublingual immunotherapy may be useful for allergic rhinitis, asthma

Research paper highlights implementation of infectious disease curriculum in Boston Public Schools

Academic medical centers launch ASD sub-registry within ResearchMatch

Auxilium Pharmaceuticals reports positive results from phase IIa Frozen Shoulder Syndrome clinical trial

Biomedical researcher discovers new technique to measure oxygen in individual red blood cells

Study projects potential impact of FDA-approved anti-obesity medications on Medicare spending

Japan's MHLW approves XELJANZ for treatment of adults with rheumatoid arthritis

New guidance highlights risk factors and treatments for osteoporosis in postmenopausal women

Anti-inflammatory drug naproxen may exhibit antiviral activity against influenza A virus

LMU researchers identify microRNA that offers promising target for new therapies

Study shows physically active healthcare providers more likely to advise patients to lead active lifestyle

Botulism Antitoxin Heptavalent gets FDA approval for patients showing signs of botulism

Scientists identify a new way to develop potential drugs for TB

Study of genetically modified immune cells could help improve promising treatment for melanoma

Male circumcision a 'staggeringly under-utilized tool'

Effectiveness of candidate malaria vaccine decreases over time, study shows

Blocked bile ducts can be effectively treated with metal stents

Positive results from Affinium Pharmaceuticals' Phase 2a clinical trial of AFN-1252 in ABSSSI

Researchers complete phase II clinical trial of dasatinib for patients with higher-risk MDS

New biodegradable nanoparticles deliver inflammation-resolving drugs to sites of tissue injury

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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