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NIH awards ADi Phase II SBIR grant to scan Plasmodium falciparum proteome for protective antigens

Antigen Discovery, Inc. today announced that it has received a Phase II Small Business Innovation and Research award from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health. The three-year award, totaling approximately $ 2.5 million, is a continuation of a Phase I SBIR grant to scan the Plasmodium falciparum proteome for protective antigens.

13 Aug 2012

Roche MagNA Pure 96 System's CE certified IVD version launched

Today, Roche announced the launch of its new CE certified IVD version of the MagNA Pure 96 System for automated sample preparation. By providing a maximum of lot-to-lot consistency and highest quality, the new MagNA Pure 96 System is designed to even better fulfill the needs of diagnostic customers. In 2011, the IVD version of MagNA Pure 96 was already introduced in the US.

From Roche Sequencing and Life Science 13 Aug 2012

First Edition: August 13, 2012

Kaiser Health News staff writer Jordan Rau reports: "More than 2,000 hospitals - including some nationally recognized ones - will be penalized by the government starting in October because many of their patients are readmitted soon after discharge, new records show".

13 Aug 2012

Maternal obesity and neonatal death: an interview with Dr. Jenny Cresswell

It is important to say that levels of maternal obesity in sub-Saharan Africa are low by global standards, but obesity is projected to increase over the next two decades.

13 Aug 2012

Verastem second quarter net loss increases to $6.8 million

Verastem, Inc., a biopharmaceutical company focused on discovering and developing drugs to treat breast and other cancers by targeting cancer stem cells, today reported financial results for the quarter ended June 30, 2012, and also commented on certain corporate accomplishments and plans.

13 Aug 2012

Scientists discover new class of polymers that are resistant to bacterial attachment

Using state-of-the-art technology scientists at The University of Nottingham have discovered a new class of polymers that are resistant to bacterial attachment. These new materials could lead to a significant reduction in hospital infections and medical device failures.

13 Aug 2012

Radiation therapy following lumpectomy may benefit older, early-stage breast cancer patients

For the majority of older, early-stage breast cancer patients, radiation therapy following breast conserving surgery may help prevent the need for a later mastectomy, according to research from The University of Texas MD Anderson Cancer Center.

13 Aug 2012

New 3-D view of the body's response to infection

A new 3-D view of the body's response to infection - and the ability to identify proteins involved in the response - could point to novel biomarkers and therapeutic agents for infectious diseases.

13 Aug 2012

Insight into ubiquitin system

A faulty gene linked to a rare blood vessel disorder has led investigators to discover a mechanism involved in determining the fate of possibly thousands of proteins working inside cells.

13 Aug 2012

Medical ethics: an interview with Anita Silvers

Medical ethics assists healthcare professionals to make decisions respectful of persons who happen to be their patients.

13 Aug 2012

Leukoaraiosis modifies brain function in the elderly

Researchers at the Mayo Clinic say a common condition called leukoaraiosis, made up of tiny areas in the brain that have been deprived of oxygen and appear as bright white dots on MRI scans, is not a harmless part of the aging process, but rather a disease that alters brain function in the elderly.

13 Aug 2012

Six ONR-funded researchers receive Presidential Early Career Awards for Scientists and Engineers

Six researchers funded by the Office of Naval Research (ONR) were honored with Presidential Early Career Awards for Scientists and Engineers (PECASE), the nation's highest honor for young scientists and engineers, officials announced Aug.10.

13 Aug 2012

HDAC8 gene mutations cause Cornelia deLange syndrome

Genetics researchers have identified a key gene that, when mutated, causes the rare multisystem disorder Cornelia deLange syndrome (CdLS). By revealing how mutations in the HDAC8 gene disrupt the biology of proteins that control both gene expression and cell division, the research sheds light on this disease, which causes intellectual disability, limb deformations and other disabilities resulting from impairments in early development.

13 Aug 2012

Johns Hopkins CIDR receives NIH contract to study genetic diseases

The Johns Hopkins Center for Inherited Disease Research (CIDR) program contract, which provides up to $101 million in research funding from the National Institutes of Health (NIH) to study the genetic contribution to human diseases, has been renewed for another five years.

13 Aug 2012

Scientists discover why major depression or chronic stress can cause loss of brain mass

Major depression or chronic stress can cause the loss of brain volume, a condition that contributes to both emotional and cognitive impairment. Now a team of researchers led by Yale scientists has discovered one reason why this occurs - a single genetic switch that triggers loss of brain connections in humans and depression in animal models.

13 Aug 2012

Research focuses on evolution of sex and gamete function

The propagation of every animal on the planet is the result of sexual activity between males and females of a given species. But how did things get this way? Why two sexes instead of one? Why are sperm necessary for reproduction and how did they evolve? These as-yet-unresolved issues fascinate Timothy Karr, a developmental geneticist and evolutionary biologist at Arizona State University's Biodesign Institute.

13 Aug 2012

Scientists discover how pten gene causes brain changes that lead to autism-like behavior

Scientists affiliated with the UC Davis MIND Institute have discovered how a defective gene causes brain changes that lead to the atypical social behavior characteristic of autism. The research offers a potential target for drugs to treat the condition.

13 Aug 2012

Reducing copper in the body delays onset of prion disease

Many of us are familiar with prion disease from its most startling and unusual incarnations-the outbreaks of "mad cow" disease (bovine spongiform encephalopathy) that created a crisis in the global beef industry. Or the strange story of Kuru, a fatal illness affecting a tribe in Papua New Guinea known for its cannibalism. Both are forms of prion disease, caused by the abnormal folding of a protein and resulting in progressive neurodegeneration and death.

13 Aug 2012

Brain activity rapidly changes in olfactory regions following odor deprivation

Has a summer cold or mold allergy stuffed up your nose and dampened your sense of smell? We take it for granted that once our nostrils clear, our sniffers will dependably rebound and alert us to a lurking neighborhood skunk or a caramel corn shop ahead. That dependability is no accident. It turns out the brain is working overtime behind the scenes to make sure the sense of smell is just as sharp after the nose recovers.

13 Aug 2012

Pressure builds on presidential nominees on health care issues, a GOP running mate

The presidential race picks up with conservatives pushing presumptive GOP nominee Mitt Romney to pick Rep. Paul Ryan, R-Wis., as his running mate while Romney's latest TV ad accuses President Obama of using his health law to "declare war" on religion.

12 Aug 2012

Research News and Research

NIH awards ADi Phase II SBIR grant to scan Plasmodium falciparum proteome for protective antigens

Roche MagNA Pure 96 System's CE certified IVD version launched

First Edition: August 13, 2012

Maternal obesity and neonatal death: an interview with Dr. Jenny Cresswell

Verastem second quarter net loss increases to $6.8 million

Scientists discover new class of polymers that are resistant to bacterial attachment

Radiation therapy following lumpectomy may benefit older, early-stage breast cancer patients

New 3-D view of the body's response to infection

Insight into ubiquitin system

Medical ethics: an interview with Anita Silvers

Leukoaraiosis modifies brain function in the elderly

Six ONR-funded researchers receive Presidential Early Career Awards for Scientists and Engineers

HDAC8 gene mutations cause Cornelia deLange syndrome

Johns Hopkins CIDR receives NIH contract to study genetic diseases

Scientists discover why major depression or chronic stress can cause loss of brain mass

Research focuses on evolution of sex and gamete function

Scientists discover how pten gene causes brain changes that lead to autism-like behavior

Reducing copper in the body delays onset of prion disease

Brain activity rapidly changes in olfactory regions following odor deprivation

Pressure builds on presidential nominees on health care issues, a GOP running mate

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

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