Efficacy News and Research

RSS

Eritoran drug does not reduce risk of death in patients with severe sepsis

Administration of the drug eritoran to patients with severe sepsis and septic shock failed to demonstrate a significant effect on reducing all-cause 28-day mortality or 1-year mortality, compared with placebo, according to a study in the March 20 issue of JAMA.

20 Mar 2013

Zometa does not prevent bone metastases

The initial study results of the Zometa European Study (ZEUS) showed no difference in the incidence of bone metastases between the Zometa group and control arm, said Prof. Manfred Wirth during the closing and fourth plenary session of the 28th Annual EAU Congress which ends today.

20 Mar 2013

Hepatitis C and HIV co-infection treatment: an interview with Prof Boecher, Boehringer Ingelheim

Chronic hepatitis C infection is one of the most frequent chronic infectious diseases worldwide. The WHO estimates that 150 million people worldwide are chronically infected with the hepatitis C virus (HCV).

20 Mar 2013

Study finds significant variation over diuretics use in BPD patients

Even though there is little data to support the extended use of diuretic medications to help reduce fluid build-up in the lungs of premature infants, researchers at Nationwide Children's Hospital have found significant variation in how babies receive these medications at hospitals across the nation.

20 Mar 2013

Study: Despite high erectile dysfunction prevalence most patients remain untreated

Despite the high erectile dysfunction prevalence most patients receive no treatment, according to a new US study, presented at the 28th Annual EAU Congress. Undertreatment of ED continues to be common, even though the treatments have a proven efficacy and quality of life impact.

19 Mar 2013

Study examines frequency of VCF use between hospitals

The frequency of vena cava filter use to prevent migration of blood clots to the lungs in patients with acute venous thromboembolism appears to vary widely and be associated with which hospital provides the patient care, according to a study of California hospitals published Online First by JAMA Internal Medicine, a JAMA Network publication.

19 Mar 2013

Tivozanib: an interview with Stephen L. Eck, M.D., Ph.D., Vice President, Global Oncology, Astellas Pharma US, Inc. Global Development

Tivozanib is an oral, once-daily, investigational tyrosine kinase inhibitor, or TKI, that is being investigated for use in patients with advanced renal cell carcinoma (RCC), or kidney cancer.

19 Mar 2013

Mesenchymal stem cells safe, effective for treating poor graft function: Study

When a research team in China evaluated the efficacy and safety of using mesenchymal stem cells expanded from the bone marrow of non-self-donors to treat patients experiencing poor graft function after receiving transplants of non-self-donated blood stem cells (allo-HSCT), they found that the mesenchymal stem cells were both safe and effective for treating primary and secondary PGF.

19 Mar 2013

R-Tech Ueno enrolls retinitis pigmentosa patients in Phase 3 clinical study of UF-021 ophthalmic solution

R-Tech Ueno is pleased to announce the start of the patient enrollment of a Phase 3 clinical study with Unoprostone (development code UF-021) ophthalmic solution that are being developed in our company for the treatment of retinitis pigmentosa.

18 Mar 2013

Harvard’s Wyss Institute to harness Sony DADC's expertise to advance Organs-on-Chips technologies

Today the Wyss Institute for Biologically Inspired Engineering at Harvard University and Sony DADC announced a collaboration that will harness Sony DADC's global manufacturing expertise to further advance the Institute's Organs-on-Chips technologies.

18 Mar 2013

Study on neoadjuvant cisplatin-based chemotherapy presented at 28th Annual EAU Congress

At the 28th Annual EAU Congress currently ongoing in Milan until Tuesday, W. Tan and colleagues presented their study on neoadjuvant cisplatin-based chemotherapy which showed that epigenetic changes are potential key drivers in the development of chemo resistance in bladder cancer.

18 Mar 2013

Columbia University Medical Center, NewYork-Presbyterian Hospital present research works at AAN meeting

The following research from Columbia University Medical Center and NewYork-Presbyterian Hospital is being presented at the 65th annual meeting of the American Academy of Neurology, March 16-23, 2013, in San Diego.

18 Mar 2013

Umbilical cord blood stem cell transplants may be an effective alternative to treat Hurler's syndrome

Transplants of blood-forming stem cells from umbilical cord blood may be an effective alternative to transplants of matched donor bone marrow stem cells to treat children with a rare, debilitating disease known as Hurler's syndrome (HS), according to results of a study published online today in Blood, the Journal of the American Society of Hematology (ASH).

17 Mar 2013

Study shows promising benefit of combination therapy in CRPC patients

Multi-peptide vaccination therapy combined with the low-dose steroid drug dexamethasone shows promise in treating chemotherapy-naive castration resistant prostate cancer (CRPC) patients.

16 Mar 2013

USAID's pursuit of evidence-based global health agenda

As part of the Global Health Research & Development blog series, E. Callie Raulfs-Wang, research adviser at USAID's Center for Accelerating Innovation and Impact, writes in the agency's "IMPACTblog," "Whether testing the efficacy of an HIV vaccine or the marketing strategy of a new contraceptive technology, quality research, careful methodology and rigorous analysis are fundamental for acquiring evidence useful in decision-making."

16 Mar 2013

Interventional endovascular therapy is safe but does not improve MS outcomes: Study

The first controlled clinical trial to test the safety and efficacy of interventional endovascular therapy on the symptoms and progression of multiple sclerosis has found that the intervention, sometimes called the "liberation treatment," which has attracted intense interest in the global MS community, does not improve patient outcomes. In a few cases, the treatment made symptoms worse.

16 Mar 2013

New medical records software provides more personalized health care for older adult patients

Innovative medical records software developed by geriatricians and informaticians from the Regenstrief Institute and the Indiana University Center for Aging Research will provide more personalized health care for older adult patients, a population at significant risk for mental health decline and disorders.

16 Mar 2013

American Journal of Public Health publishes special issue on mental health stigma

In a historic first, the American Journal of Public Health has devoted an issue to covering stigma and discrimination against people with mental illnesses, a topic that traditionally is under-researched and under-reported.

15 Mar 2013

Article explores benefits of innovative programs for personalized health care

Two innovative programs designed to improve the availability of emerging medical technologies that can help patients receive more effective, efficient and personalized health care are advanced in a commentary written by a team of scientists and policy experts, including seven from Arizona State University, and published today in Science Translational Medicine.

15 Mar 2013

Researchers find no overall recovery benefit to patients treated with clot-removal devices

When someone has a stroke, time equals brain. The longer a stroke is left untreated, the more brain tissue is lost. Since the only proven treatment - a clot-busting drug - works in less than half of patients, stroke physicians had high hopes for a mechanical device that could travel through the blocked blood vessel to retrieve or break up the clot, restoring blood flow to the brain.

15 Mar 2013

Efficacy News and Research

Eritoran drug does not reduce risk of death in patients with severe sepsis

Zometa does not prevent bone metastases

Hepatitis C and HIV co-infection treatment: an interview with Prof Boecher, Boehringer Ingelheim

Study finds significant variation over diuretics use in BPD patients

Study: Despite high erectile dysfunction prevalence most patients remain untreated

Study examines frequency of VCF use between hospitals

Tivozanib: an interview with Stephen L. Eck, M.D., Ph.D., Vice President, Global Oncology, Astellas Pharma US, Inc. Global Development

Mesenchymal stem cells safe, effective for treating poor graft function: Study

R-Tech Ueno enrolls retinitis pigmentosa patients in Phase 3 clinical study of UF-021 ophthalmic solution

Harvard’s Wyss Institute to harness Sony DADC's expertise to advance Organs-on-Chips technologies

Study on neoadjuvant cisplatin-based chemotherapy presented at 28th Annual EAU Congress

Columbia University Medical Center, NewYork-Presbyterian Hospital present research works at AAN meeting

Umbilical cord blood stem cell transplants may be an effective alternative to treat Hurler's syndrome

Study shows promising benefit of combination therapy in CRPC patients

USAID's pursuit of evidence-based global health agenda

Interventional endovascular therapy is safe but does not improve MS outcomes: Study

New medical records software provides more personalized health care for older adult patients

American Journal of Public Health publishes special issue on mental health stigma

Article explores benefits of innovative programs for personalized health care

Researchers find no overall recovery benefit to patients treated with clot-removal devices

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News